BALLYA Colistin Test is manufactured by BALLYA, it’s rapid test for detection colistin residues in feed product and food, especially in feed. Lateral flow assay test base on the gold immunochromatography assay technology.
Colistin is also called polymyxin E. Polymyxin E is a basic peptide antibiotic produced by BacillusPoliusPolymyxaVarColistinus. It has a strong bactericidal effect on Gram-negative bacilli and can treat animals caused by a variety of pathogens. Feeding diseases, with good antibacterial spectrum, high efficiency and low toxicity, have been used as feed additives, and can promote animal biology and improve feed utilization.
Colistin mechanism of action
Colistin's mechanism of action and antibacterial spectrum are similar to Colistin, and it is effective against gram-negative bacteria, such as Pseudomonas aeruginosa, Escherichia coli, Bacillus pertussis, Salmonella, Shigella, etc. This product has cross-resistance with Colistin.
Colistin production method
Extracted from the culture broth of Bacillus Polymyxa. There are five types of polymyxin A, polymyxin B, polymyxin C, polymyxin D and E. The main component of polymyxin E is polymyxin E1, which contains a small amount of polymyxin E2.
What is Colistin used for?
Used for intestinal infections caused by Escherichia coli, Salmonella, Shigella, Paracoli, Brucella, etc.
It has a good control effect on various fungal diseases such as wheat powdery mildew, cucumber downy mildew, rice sheath blight, and apple early leaf fall disease.
It can treat animal feeding diseases caused by a variety of pathogens. It has good antibacterial spectrum, high efficiency and low toxicity. It has been used as feed additives, and can promote animal biology and improve feed utilization.
What are the side effects of Colistin?
Can cause nephrotoxicity, neurotoxicity and allergic reactions. Gastrointestinal symptoms such as nausea, vomiting, loss of appetite, and diarrhea may occur. Toxicity to the kidney is to damage the renal tubules, causing proteinuria, hematuria, and tubular urine. Toxicity to the nervous system is manifested as skin paresthesia, gait instability, and movement disorders. Occasionally induce leukopenia and liver toxicity.
Precautions for using Colistin
People who are allergic to this drug should not be used. Care should be taken when renal insufficiency occurs. In addition, this product is not easy to combine with muscle relaxants and aminoglycoside antibiotics such as streptomycin, neomycin, kanamycin, and gentamicin, which can cause intramuscular weakness and apnea.
Note: The above content is only an introduction, and the use of drugs must be carried out under the guidance of a doctor in a regular hospital.
Colistin use as a veterinary medicine
It is mainly used to treat intestinal infections caused by Gram-negative bacilli (E. coli, etc.), and it is also effective against Pseudomonas aeruginosa infections (septicemia, urinary tract infections, burns or traumatic wound infections).
Usage and dosage
Oral dose per 1 kg body weight of calves, piglets 1.5~5 mg unit, poultry 3~8 mg unit 1~2 per day Times Mixed feeding: 5-40g calves per 1,000 kg feed, 2-20g germanium for young pigs, 2-20g chickens (calculated as colistin) Mixed drinking: 40~100 mg per IL water pig and 20~60 mg (calculated as colistin) for continuous use for no more than 7 days
Withdrawal period is 7 days for pigs and chickens.
Please follow the veterinarian's recommendations for specific usage and dosage.
What specimen can be detected by BALLYA Colistin Test?
Specimen include: all kinds of feeds and food. Widely used in feed industry and food processing industry. You can choose the right products according to your needs.
Significance of testing Colistin
To protect the animal have health feed, food and avoid contaminated food. The colistin is harmful for animal being, can not take too much in the body.
1. Take feed or food specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Colistin Test?
BALLYA Colistin Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
As a pharmaceutical feed additive, colistin can significantly promote weight gain and increase feed conversion rate, and is widely used in the field of livestock and poultry breeding. However, many people do not pay attention to the dosage and usage of colistin, which leads to the residue of colistin in food. Colistin is harmful to the human body and should be avoided as much as possible. The BALLYA Colistin Test provided by BALLYAcan effectively detect the colistin in the samples. Simple operation, short detection time and high accuracy are the characteristics of this product.