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Thiamphenicol Test

Thiamphenicol-Test-Kit

For Milk, Milk Powder, Pasteurized Milk

Specs:96T / box
Testing Time:7-10 mins
Regulation: CN / EU / RU / US

Operation video

Instrution For Thiamphenicol Test

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, trimethoprim, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: What is thiamphenicol?

Thiamphenicol

Thiamphenicol structure

Its chemical formula is [R- (R *, R *)] N- [1- (hydroxymethyl) -2-hydroxy-2- [4- (methylsulfonyl) phenyl] ethyl] -2,2 -Dichloroacetamide, soluble in dimethylformamide, slightly soluble in absolute ethanol, slightly soluble in water.

Thiamphenicol exterior

Thiamphenicol is white to off-white crystalline powder or crystal. It is insoluble in water but highly soluble in lipids.

How does thiamphenicol work

This product is a methylsulfone derivative of chloramphenicol. It is a synthetic broad-spectrum antibacterial drug. Its antibacterial spectrum and antibacterial effect are basically similar to chloramphenicol. It mainly diffuses into bacterial cells and reversibly binds to the 50S of bacterial ribosomes. On the subunit, the growth of the peptide chain is blocked (possibly inhibiting the effect of transpeptidase), the formation of the peptide chain is inhibited, and the synthesis of the protein is prevented, thereby playing an antibacterial effect.

Thiamphenicol uses

It is mainly used for the treatment of respiratory, urinary, hepatobiliary, typhoid and other intestinal surgery, gynecological and pediatric infections, especially for moderate to mild infections.

Thiamphenicol capsules

Thiamphenicol capsules are used for respiratory, urinary, and intestinal infections caused by sensitive bacteria such as Haemophilus influenzae, Escherichia coli, and Salmonella.

Thiamphenicol tablet

Mainly used in acute upper respiratory infections, urinary tract infections, enteritis, digestive medicine, nephrology medicine, respiratory medicine.

Thiamphenicol dosage

1. Adult: (1) Oral administration: 1.5 to 3.0 g per day, divided into 3 to 4 times. (2) Gas-soluble inhalation: 5% to 10% sulfomycin solution is available for gas-soluble inhalation. (3) Intrathoracic, intraperitoneal and intravesical administration: 0.5 to 1 g each time.
2. Oral administration for children: 25-50mg / kg daily, divided into 4 times.
3. For typhoid fever: 3g orally every day on day 1 to 3, 1.5g a day on day 4 to 6, and 1g a day thereafter;
4. For gonorrhea: a single dose of 2.5g.
5. Intramuscular injection, intravenous injection: the same dose as oral.

Thiamphenicol side effects

1. Myelosuppression: Reversible myelosuppression is the most serious adverse reaction of this drug. This response is related to the dosage and course of treatment. It is common in patients whose blood concentration exceeds 25 μg / ml. Clinical manifestations are anemia, and can be associated with leukocytes and thrombocytopenia.
2. Aplastic anemia: Aplastic anemia is rare after medication. Its clinical manifestations include bleeding tendency due to thrombocytopenia, concurrent stasis, ecchymosis, and nosebleeds, as well as signs of infection caused by granulocytopenia, such as fever, sore throat, and jaundice.
3. Gray infant syndrome: There have been no reports of "gray infant syndrome" caused by the use of this drug in preterm infants and newborns.
4. Hepatotoxicity: People with existing liver disease may cause jaundice, liver fat infiltration, and even acute severe hepatitis.
5. Allergic reactions: Allergic reactions such as rash, solar dermatitis, angioedema, and drug fever are rare after taking the drug, and the general symptoms are mild.
6. Nervous system: Peripheral neuritis and optic neuritis can occur after long-term medication, manifested as neurological symptoms such as hearing loss, insomnia, hallucinations, delirium, etc., which are mostly reversible. Optic nerve atrophy and blindness have also been reported after long-term use.
7. Gastrointestinal reactions: Gastrointestinal symptoms such as loss of appetite, nausea, vomiting, epigastric discomfort, and diarrhea are more common after administration, and the incidence is less than 10%.
8. Double infection: After long-term use, the normal flora in the body can be reduced, causing double infection.
9. Others: (1) Some patients with congenital glucose-6-phosphate dehydrogenase deficiency may develop hemolytic anemia after administration; (2) Long-term oral administration may inhibit the intestinal flora and block vitamin K synthesis. Induces bleeding tendency.

Summary

Thiamphenicol is a very important chemical, many countries and regions use it as a veterinary antibiotic for the treatment to diseases of livestock, poultry and pets. Especially in dairy farming the frequency of use is quite high. Therefore, the phenomenon of methamphenicol residues may appear in cows and even milk. Absorption of excessive sulfomycin can cause great harm to human health. It is very important to avoid residual methamphenicol, and detection and prevention is a very effective method. Ballya provides a quick test kit for methamycin, which will let you know if milk is safe in a short time. The test results comply with EU standards, which is not only simple to operate, but also highly accurate and fast.

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