BALLYA Furazolidone Test is manufactured by BALLYA, it’s rapid test for detection furazolidone residues in chicken meat and bee product, especially in chicken meat. Lateral flow assay test base on the gold immunochromatography assay technology.
Antibacterial effect on Gram-positive and negative bacteria, including Salmonella, Shigella, E. coli, Klebsiella pneumoniae, Enterobacter, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, Cholera Vibrio, Campylobacter and Bacteroides are also active against Trichomonas and Giardia under certain concentrations. Its mechanism of action is to interfere with bacterial oxidoreductase and thereby block the normal metabolism of bacteria.
Furazolidone synthesis
1. Ethanolamine is used as a raw material to condense with urea to obtain β-hydroxyethyl urea, which is nitrosated and cyclized to obtain 3-nitroso-2-azolidinone. Further reduction with iron powder and condensation with 5-nitro-2-furfuryl glycol diacetate and formaldehyde yield furazolidone. 2. Condensation of ethanolamine with urea, nitrosation and cyclization with sodium nitrite, and finally reduction with iron powder with 5-nitro-2-furfuryl glycol diacetate and formaldehyde to obtain furazolidone.
How Furazolidone uses for?
Furazolidone spray
Furazolidone spray is specifically for the treatment of horses, for topical application in horses and ponies. For the prevention or treatment of superficial wounds, abrasions and lacerations caused by Staphylococcus aureus and Streptococcus. And Proteus. Sensitive to furazolidone. Not suitable for animals intended for food. Use only as recommended by a veterinarian to treat puncture wounds, wounds that require surgical debridement or sutures, pride of meat, systemic and chronic infections of the skin, and chronic wounds of skin conditions associated with intense itching. If redness, inflammation or swelling persists or worsens, discontinue use and consult a veterinarian. Wear gloves when washing or wash hands afterwards. Avoid contact with eyes.
What's Furazolidone side effect?
Mainly nausea, vomiting, diarrhea, headache, dizziness, drug fever, rash, anal itching, asthma, orthostatic hypotension, hypoglycemia, pulmonary infiltration, etc. Occasionally hemolytic anemia, jaundice and polyneuritis may occur.
Furazolidone toxic
Excessive use of furazolidone may cause gastrointestinal reactions (such as nausea, vomiting, anorexia, diarrhea, and generally mild reactions); allergic reactions such as hemolytic anemia, rash, drug fever; polyneuritis; newborns and G-6- PH deficiency can cause hemolytic anemia. Overdose or long-term continuous medication can cause animal poisoning and severely cause animal death. It can cause irreversible damage to the central nervous system, and can cause diseases such as hemolytic liver necrosis in the human body. As early as 2002, the Ministry of Agriculture listed it as a banned veterinary drug and it is strictly prohibited to use it in any food animal. However, in order to pursue economic benefits, some farmers still use it as a special medicine for treating aquatic gastrointestinal diseases. Studies have also shown that furazolidone for long or high doses has varying degrees of toxic and side effects on liver, kidney, heart, hypothalamus and reproductive systems of animals.
Furazolidone interaction
(1) Combination with tricyclic antidepressants can cause acute toxic psychosis and should be avoided. (2) This product can enhance the effect of levodopa. (3) Sympathomimetic amines, tyramine-rich foods, appetite suppressants, monoamine oxidase inhibitors, etc. can enhance the effect of this product.
Furazolidone use as a veterinary medicine
When used as a veterinary drug, furazolidone has a good effect on the prevention and treatment of certain protozoan diseases, water mold diseases, bacterial rotten gills, erythroderma, and bleeding diseases. In the breeding industry, furazolidone can be used to treat intestinal infections in livestock and poultry, such as piglet yellow and white pheasant. In the aquaculture industry, furazolidone has a certain effect on the infection of cerebral myxosoma by Salmonella. Furazolidone is listed by the Ministry of Agriculture of the People's Republic of China as a banned drug and cannot be detected in animal foods.
Furazolidone for dogs
It is usually used to treat intestinal infections and coccidiosis in dogs, and it is effective against E. coli and dysentery.
Furazolidone for fish
Furazolidone is the main component of tetriline, an ornamental fish medicine "yellow powder", which can interfere with the bacterial sugar metabolism process and oxidase system and exert bacteriostatic or bactericidal effects. So it can be used to treat bacterial diseases of ornamental fish disease. And the effect is very good.
Furazolidone in poultry
Furazolidone is highly toxic, and it is not easy to control the middle dosage or uneven mixing, and it is easy to be poisoned and even cause the death of chickens. Due to the short breeding period of broilers, if furazolidone is used to prevent and treat diseases, slaughtering is often carried out because the drug has not been excreted cleanly, resulting in the drug remaining in the chicken, causing human drug poisoning after human consumption, affecting human health. Therefore, furazolidone is strictly prohibited in the feeding process of fast large broilers.
What specimen can be detected by BALLYA Furazolidone Test?
Specimen include: chicken meat, bee product etc. Widely used in chicken meat and bee product industry.
Significance of testing Furazolidone
To protect human have health food and avoid contaminated food. The Furazolidone is harmful for human being, can not take too much in body.
1. Take chicken meat specimen and extrat supernatant or bee product specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Furazolidone Test?
BALLYA Furazolidone Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
Conclusion
As a veterinary drug, this product is absorbed orally quickly but not completely. It is widely distributed in animals and can enter tissues and body fluids well. Mainly excreted from urine in the form of original drugs. But it is inevitable that there will be residual drugs left in the body. This is likely to cause furazolidone residues in chicken. It is necessary to detect furazolidone in chicken. BALLYA Furazolidone Test provided by BALLYA can effectively and quickly detect whether chicken contain furazolidone residues. Not only is the operation simple and the detection time is short, it allows the tester to obtain the test results in the first time.
