BALLYA Marbofloxacin Test is manufactured by BALLYA, it’s rapid test for detection marbofloxacin residues in honey & bee product, especially in honey. Lateral flow assay test base on the gold immunochromatography assay technology.
Marbofloxacin is a fluoroquinolone antibacterial drug for veterinary use, with a chemical name of 9-fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxygen Substitute-7H-pyridine [3, 2, 1-i, j] [4. 1.2] benzodiazine-6-carboxylic acid, developed by Roche, further developed by Ve'toquinol, in 1995 successively in England, French listing. This product has a strong antibacterial effect, a long elimination half-life, and a bioavailability close to 100%.
Marbofloxacin mechanism of action
Marbofloxacin is a new type of fluoroquinolone antibacterial. It inhibits the growth of bacteria by inhibiting the DNA transcriptase of bacteria. It has antibacterial effects on gram-negative bacteria, gram-positive bacteria and mycoplasma. Marbofloxacin can be well absorbed through oral and injection administration, with low side effects.
How Marbofloxacin uses for?
Fluoroquinolones are used to treat deep and superficial skin infections, urinary tract infections in dogs, skin and soft tissue infections in cats, and acute upper respiratory tract infections. Used for respiratory tract, digestive tract, urinary tract and skin infections of cattle, pigs, dogs and cats caused by sensitive bacteria. It is also effective for bovine and goat mastitis and swine mastitis-metritis-agalactia syndrome. Withdrawal period: 6 days for cattle or 1.5 days for milk abandonment period; 2 days for pigs.
Marbofloxacin usage and dosage
Intramuscular injection once per 1 kg body weight, cattle and pig 2 mg once a day Orally taken once per 1 kg body weight of livestock 2 mg once a day [Preparation and specifications] Marbofloxacin tablets (1) 5 mg (2) 20 mg (3) 80 mg Marbofloxacin injection 1mL: 100 mg
What's Marbofloxacin side effect?
In addition to potentially causing cartilage abnormalities in young animals, the adverse effects of marbofloxacin are usually limited to gastrointestinal reactions (vomiting, loss of appetite, soft stools, diarrhea) and decreased activity.
Regarding the adverse reactions caused by other fluoroquinolones: It has been reported in dogs that it can increase the activity of liver drug-metabolizing enzymes, causing symptoms such as dyskinesia, seizures, depression, lethargy and nervousness, but the incidence is very low. Allergic reactions and crystaluria also occur. In cats, high doses of enrofloxacin have been reported to cause visual toxicity, but whether marbofloxacin can also cause similar toxicity is unclear.
Marbofloxacin contraindications
Like other quinolone drugs, Marbofloxacin is banned for use in small and medium-sized animals under 8 months of age, large animals under 12 months of age, giant animals under 18 months of age, and cats under 12 months of age. . Fluoroquinolones are also contraindicated in affected animals with allergic reactions. Marbofloxacin can (rarely) cause central nervous system reactions, and patients with epilepsy should be cautious when using it. The FDA has banned the use of this drug in food animals.
Marbofloxacin interaction
Marbofloxacin is combined with aminoglycosides, third-generation cephalosporins, and broad-spectrum penicillins. It may have a synergistic effect when inhibiting some bacteria (especially Pseudomonas aeruginosa and Enterobacteriaceae), but not predicted. Although Marbofloxacin has very low activity against anaerobic bacteria, when it is used together with clindamycin, it has been reported to inhibit the in vitro synergistic effect of Peptostreptococcus, Lactobacillus and Bacteroides fragilis. Nitrofurantoin may antagonize the antibacterial activity of fluoroquinolones, so their simultaneous use is not recommended. Fluoroquinolones may accelerate the nephrotoxicity of cyclosporine A.
What specimen can be detected by BALLYA Marbofloxacin Test?
Specimen include: honey, bee products, etc. Widely used in honey industry and bee products industry.
Significance of testing Marbofloxacin
To protect human have health food and avoid contaminated food. The marbofloxacin is harmful for human being, can not take too much in body.
1. Take bee products specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Marbofloxacin Test?
BALLYA Marbofloxacin Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
Conclusion
Marbofloxacin has been widely used as an anabolic hormone in various industries. The bee breeding industry deserves special attention. Bee products provide people with rich nutrition, making them indispensable in daily life. The problem of marbofloxacin residues in bee products has always plagued people, so it is necessary to detect bee products in time. BALLYA Marbofloxacin Test provided by BALLYA can effectively and quickly detect the presence of Marbofloxacin residues in bee products. Not only the operation is simple, the test time is short, but the tester can get the test result in the first time.
