Erythromycin is white or off-white crystal or powder; odorless, bitter taste; slightly hygroscopic. It is easily soluble in methanol, ethanol or acetone, and slightly soluble in water.
Its free base is for oral use, and lactobionate is for injection. In addition, there are still ethyl succinate (erythromycin ethylsuccinate), dodecyl sulfate of propionate (erythromycin estolate) for medicinal use.
2. Mechanism of action
Erythromycin can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site (P site), blocking transfer ribonucleic acid (t-RNA) from binding to the P site, and at the same time blocking peptides chain transferring from the acceptor site (A site) to the P site, thereby inhibiting bacterial protein synthesis.
Erythromycin is a macrolide antibacterial drug. Its effect on gram-positive bacteria is similar to penicillin, but its antibacterial spectrum is broader than penicillin. The sensitive gram-positive bacteria include Staphylococcus aureus (including penicillin-resistant golden yellow Staphylococcus), pneumococcus, streptococcus, Bacillus anthracis, Listeria, Clostridium putrefaction, Clostridium emphysema, etc. Sensitive Gram-negative bacteria include Haemophilus influenzae, Meningococcus, Brucella, Pasteurella, etc.
In addition, erythromycin also has a good effect on Campylobacter, Mycoplasma, Chlamydia, Rickettsia and Leptospira. The antibacterial activity of erythromycin in alkaline solution increases. When the pH rises from 5.5 to 8.5, the antibacterial activity gradually increases.
3. Effects of Erythromycin
Erythromycin thiocyanate is mainly used for serious infections caused by resistant Staphylococcus aureus and hemolytic streptococcus, such as pneumonia, sepsis, endometritis, mastitis, etc. It also has a good effect for chronic respiratory diseases of poultry caused by mycoplasma, Swine mycoplasma pneumonia, and it is also used for the treatment of nocardiasis in dogs and cats.
Erythromycin thiocyanate can also prevent the white heads and white mouths of fry and fish species, diseases such as bacterial gill rot disease in grass carp and herring, white skin disease in silver carp and bighead carp, and streptococcal disease in tilapia.
It is often used as an alternative medicine for animals allergic to penicillin. It is mainly used for various infections caused by penicillin-resistant Staphylococcus aureus and other sensitive bacteria, such as pneumonia, metritis, mastitis, and sepsis.
The harm of erythromycin
Erythromycin is a macrolide antibiotic. It is mainly used to fight against bacterial and mycoplasma infections in livestock and poultry. It can also be used as a feed additivefor pigs to promote weight gain and increase feed conversion rate. It is used in livestock and aquatic product breeding and diseases widely used in the treatment process.
However, erythromycin compounds can have some side effects on the body, such as gastrointestinal reactions, cholestatic jaundice and phlebitis caused by intravenous infusion, and can also cause necrotizing liver disease, mental disorders and arthritis syndrome.
Therefore, large-scale use of erythromycin in the production will cause residues in livestock and poultry tissues, honey, milk, fish and shrimp, and endanger public health. At present, the document No. 235 of the Ministry of Agriculture has stipulated that the maximum residue limit of the drug is 200ug/kg.
Features of Erythromycin Test
1. 7min reading results
2. Detection limits respond to EU and US FDA norms
3. Neither professionals nor equipment required
4. Easy to operate and read
Detection Method of Erythromycin Test
Erythromycin Test, based on colloidal gold competition method, is used for testing Erythromycin residues in milk sample and meets EU MRL. This kit can be applied for on-site rapid testing by various departments.
Samples of Erythromycin Test
Samples include: raw milk, milk powder, pasteurized milk.
Detection Limit of Erythromycin Test
The LOD may change according to requirement or specimen's difference, please refer to kit instruction for further details.
Importance of Erythromycin Test
Erythromycin Test can help manufacturers, regulatory agencies, and the general public monitor product quality and help humans protect their health.
Components of Erythromycin Test
1. Micro-Well Reagent: 8 tests/tube, 12 tubes/box
2. Test Strip: 8pcs/tube, 96pcs/box
3. Manual Instruction: 1pc
Materials for Erythromycin Test
1. Sample Tube
2. Pipette & Pipette Tip
How to use Erythromycin Test?
1. Add 200ul milk into a well, then pipet up and down for 10 times to completely mix the sample with the reagent in the well.
2. Then incubate for 5min.
3. Insert the test strip into the micro-well-plate with the sample pad fully dipped.
4. After 5 minutes, read the results.
When antibiotics were first used on humans, we regarded them as "magic drugs". As the problem of antibiotic abuse continues to worsen, their resistance has also brought huge harm to humans.
Therefore, in daily life, we should avoid food with antibiotic residues. The first step to self-help: we need to detect antibiotic residues.
How to order Erythromycin Test?
Please check the online catalog and contact our sale representative via email: firstname.lastname@example.org or fill out contact form below: