Mycoplasma is the smallest microorganism that survives outside the cell. It is a prokaryotic cell-type microorganism lacking a cell wall. The size is usually between 0.3 and 0.5um. It is highly polymorphic, with spheres, rods, filaments, and branches. A state. It is different from bacteria and viruses. It has many types and is widely distributed, causing considerable harm. It involves humans, animals, plants and insects, and has adversely affected human health and scientific research. Of the 16 species of Mycoplasma isolated from the human body, 5 are pathogenic to humans, namely Mycoplasma pneumoniae, Mycoplasma urealyticum, Mycoplasma humani, Mycoplasma genitalium and Mycoplasma fermentum are ureaplasma urealyticum, Mycoplasma urealyticum and Mycoplasma humani.
What is Mycoplasma pneumonia?
Mycoplasma pneumonia is an acute respiratory infection associated with pneumonia caused by mycoplasma pneumonia. Mycoplasma pneumoniae is the most common pathogen in the past and is called "primary atypical pneumonia." Can cause epidemics, accounting for about 10% of various pneumonia, severe mycoplasma pneumonia can also lead to death.
Mycoplasma pneumonia symptoms
The incubation period is 2 to 3 weeks, the onset is slow, and about 1/3 of the patients are asymptomatic. It occurs in the form of tracheobronchitis, pneumonia, tympanitis, etc., among which pneumonia is the most severe. At the beginning of the attack, there are fatigue, headache, sore throat, chills, fever, muscle aches, loss of appetite, nausea, vomiting, etc. The headache is obvious. Fever up to 39 °C. Significant respiratory symptoms appear after 2 to 3 days, such as paroxysmal irritating cough, small amounts of mucus or purulent mucus, and sometimes blood in the sputum. Fever can last 2 to 3 weeks. After the fever returned to normal, there was still a cough and pain under the sternum, but no chest pain. Physical examination revealed mild congestion of the nose, runny nose and moderate congestion of the pharynx. The tympanic membrane is often hyperemic, and about 15% have tympanitis. Swollen lymph nodes in the neck. A few cases have maculopapular rash, erythema, or cold sores. There are usually no obvious abnormal signs on the chest, dry or wet rales can be heard in about half, and a small amount of pleural effusion occurs in 10% to 15% of cases.
Mycoplasma pneumonia treatment
Isolate the airways, rest, and provide adequate water and nutrition. Symptomatic treatment: avoid salicylic acid drugs to prevent hemolysis. Generally, antipyretic and analgesics with slow and long-acting effects, such as acetophenone, carbachol calcium, lysine, and Bupleurum, are selected and supplemented with a physical cooling effect during high fever. Resolving Phlegm and Cough. Remove nasal secretions and keep the airway open, nebulizing and inhaling if necessary.
The Mycoplasma in dogs
Symptoms of mycoplasma infection in dogs
First, pneumonia. My dog's cough or other symptoms of lung disease may be mycoplasma infection; Second, inflammation and reproductive organ infections, inflammation and redness in dogs' genitals may be mycoplasma infections; Third, dogs need to go to animal hospitals for specific inspections to determine whether it is a Mycoplasma infection. Generally, the cure rate of Mycoplasma infection is high.
Causes of mycoplasma infection in dogs
The cause of mycoplasma canis infection is a combination of exposure to bacteria and the overall health of the immune system. Usually, the immune system of a healthy dog can fight off the infection, but when the immune system is damaged, the dog is more susceptible to infection. Mycoplasma bacteria. Another bacterial or viral infection can suppress the immune system. Certain chemotherapy, such as chemotherapy or immunosuppressants, can also suppress the immune system. Any long-term or chronic disease may also reduce the immune system's ability to resist Mycoplasma bacteria.
Treatments for mycoplasma infection in dogs
Some antibiotics that attack the cell wall are not effective against Mycoplasma because the bacterial family does not have a cell wall. Usually, mycoplasma infection is prescribed with tetracycline and doxycycline.
How to treat mycoplasma disease or Mycoplasma hyopneumoniae?
Early use of appropriate antimicrobials can reduce symptoms and shorten the course of the disease. The disease is self-limiting and most cases require no treatment. More. Macrolides are preferred, such as erythromycin, roxithromycin, and azithromycin. Fluoroquinolones such as levofloxacin, gatifloxacin and moxifloxacin are also used to treat mycoplasma pneumoniae pneumonia. The course of treatment is usually 2 to 3 weeks. Because Mycoplasma pneumoniae does not have a cell wall, antibacterial drugs such as penicillin or cephalosporins are not effective. For severe cough, appropriate antitussives should be taken. If a secondary bacterial infection occurs, it can be treated with targeted antimicrobials based on the cause of the sputum.
Mycoplasma hyopneumoniae treatment
Mycoplasma hyopneumoniae belongs to the genus Mycoplasma, which is not a bacterium or a virus, but as long as it is alive, it is a protein, so drugs that inhibit protein synthesis are preferred. There are two types of drugs that inhibit protein synthesis: The first is antibiotics that bind to the bacterial ribosomal 50S subunit and block transpeptides and mRNA shifts, such as macrolides (telmicoxin, tylosin, azithromycin, guitaromycin, erythromycin), amide Alcohols (flufenicol), diterpenes (mycoplasma-tiamulin), lincomamin (lincomycin), etc. The second is antibiotics that bind to the bacterial ribosome 30S subunit and prevent the aminoacyl transport RNA from binding to the ribosome, such as tetracyclines (doxycycline) and aminoglycosides (kanamycin). When diagnosed as mycoplasma, flufenicol and doxycycline control are preferred.
Mycoplasma hyopneumoniae prevention
Since Mycoplasma hyopneumoniae has only one serotype, vaccine immunization is the most effective prevention method. Although traditional respiratory medicines cannot treat mycoplasma hyopneumoniae pneumonia, it can control and relieve them to a certain extent.
Mycoplasma hyopneumoniae vaccine
Immunization is required before the piglets are infected with Mycoplasma. The immune protection effect will be very good, and the protection time will be long. Since it is impossible to predict when piglets will become infected, vaccination should be carried out as soon as possible after birth. In addition, early immunization should take into account whether maternal antibodies will adversely affect the vaccine. Of course, choosing a high-quality vaccine and formulating a reasonable immunization program (such as two intramuscular injections at one or three weeks of age) are also important for the immune effect. Because pigs are infected with Mycoplasma pneumoniae, they are often prone to secondary infections with other bacteria and viruses. Therefore, vaccination can not only protect pigs from Mycoplasma pneumoniae, but also prevent infection by other secondary pathogens, and provide pigs with broader protection.
Which animals can be detected by the BALLYA Mycoplasma test?
Pigs, household pets, etc. can use the BALLYA MycoplasmaTest for mycoplasma detection. In the future, BALLYA will conduct more studies on mycoplasma in different types of animals. You can choose according to your needs.
Significance of testing Mycoplasma
In order to ensure the safety of consumers, reduce the economic loss of the owner of the breeding plant, prevent the sick pigs from entering the market, and treat the sick pigs in time, the Mycoplasma Test can play a key role. Ensure the safety of farm owners and consumers, reduce unnecessary losses.
1. Pipetting the whole blood, centrifuge for 5-15 minutes at 2000-3000 r/m to separate the serum. It can also be left standing overnight at 4ºc to separate out the serum. Or test the whole blood without anticoagulant immediately. 2. Take out and place the card on the flat desk. 3. Absorb the sample and add 3 drops into the sample well carefully. 4. Read the result for 10-20 minutes. The result after 20 minutes is invalid.
Limitations of BALLYA Mycoplasma Test?
BALLYA Mycoplasma Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
For a long time, mycoplasma disease has been considered as one of the most frequent and most difficult epidemic diseases that cause major economic losses to the pig industry and family with pets. Although the disease is old, in recent years, it has become important because it is often mixed with other pathogens such as PRRS and circovirus, causing significant economic losses. BALLYA Mycoplasma Test provided by BALLYA can effectively detect whether pigs or pets have Mycoplasma disease. This kit is not only simple to operate, but also has a short test time and high accuracy. Allow the veterinarian to respond accordingly.