Pseudorabies Test For Pig (Ab)

Pseudorabies (PR, also known as Aujeszky's disease, AD) is an infectious disease caused by Pseudorabies Virus (PRV). The disease was first discovered in the United States, and later the virus was first isolated by Hungarian scientists. In the middle of the 20th century, PR was widespread in Eastern Europe and the Balkans. Before the 1960s, the symptoms of pigs were mild after infection and did not cause significant economic losses in the pig industry.

Porcine pseudorabies is an acute infectious disease in pigs caused by Pseudorabies virus (PrV). The disease is endemic in pigs. It can cause abortion of pregnant sows, stillbirths, infertility of boars, mass death of newborn piglets, dyspnea and growth retardation of fattening pigs, etc. It is one of the major infectious diseases that endanger the global pig industry.

There are four major symptoms of swine pseudorabies:
(1) Abortion, stillbirth, and mummification occur in pregnant sows.
(2) Pseudo-rabies causes a large number of newborn piglets to die, which is mainly manifested in the fact that piglets that were just born were still very good on the first day, and the onset of the disease began on the second day. The peak of death occurred in 3 to 5 days, and some died in the whole litter. The age of dead newborn piglets has been observed at 19 days of age. The affected piglets showed high fever, loss of appetite, obvious neurological symptoms, lethargy, whine, drooling, vomiting, diarrhea, depression and tremor, followed by dyskinesia, intermittent convulsions, coma and even failure to die. Once the disease occurs, within 1 to 2 days death. The mortality of piglets within 15 days can reach 100%. Post-mortem examinations are mainly covered with needle-point bleeding points in the kidneys, and pulmonary edema, meningeal surface congestion, and bleeding are sometimes seen.
(3) Pseudo-rabies virus causes weaned piglets to die, with an incidence of 20% to 40% and a mortality of 10% to 20%. The main manifestations are neurological symptoms, diarrhea, and vomiting.
(4) Sterility of breeding pigs. The sow is not in estrus and is not suitable for breeding. The return rate is as high as 90%. Repeated breeding has failed repeatedly, which delays the entire breeding period. In addition, boars infected with pseudorabies virus showed infertility, testicular swelling, atrophy, and loss of breeding ability. Adult pigs show only mild symptoms such as slower weight gain.

In the diagnosis, it should be noted that the disease is not easy to distinguish from swine fever, blue ear disease, parvovirus, Japanese encephalitis and other diseases, and laboratory tests must be performed to confirm the diagnosis.

Porcine pseudorabies virus belongs to the herpesvirus family in terms of pathogen classification. Pseudorabies is an acute infectious disease with fever and strange itching (except pigs) and encephalomyelitis as the main symptoms of a variety of domestic animals and wild animals.

Pseudorabies virus particles are oval or round in shape. The genome is a linear dsDNA molecule with a molecular weight of 87 × 106 (about 150 kb), a (G + C) mol% content of 73%, and an icosahedron with three-dimensional symmetry. Virus particles with no envelope in the nucleus are about 110-150 nm in diameter, and mature virus particles with envelope in the cytoplasm are about 150-180 nm in diameter. Spikes are arranged radially on the surface of the envelope, and the length is about 8-10 nm.

There is no effective treatment for this disease, as long as prevention is the first step. If disease can be treated with porcine serum antibodies.

Vaccine immunization is a fundamental measure for the prevention and control of pseudorabies. Purification of pigs is the main method. Purification from breeding herds is carried out. mode. Strengthen daily management of herds.

(1) Reserve pigs should be immunized with pseudorabies vaccine at least twice before breeding, and gene-deficient attenuated vaccines can be used for both times.
(2) Immunized sows should be immunized 1-2 times in the second trimester (20-40 days before delivery or 75-95 days after breeding) according to the degree of infection in the field. Sows can be immunized with inactivated vaccines or gene-deleted attenuated vaccines. At least one of the two immunizations should use gene-deleted attenuated vaccines. Pregnant sows who have been immunized twice before 20-40 days before delivery will use genetic deletion for the first time. Attenuated vaccine, it is safer to use propolis to inactivate the vaccine for the second time.
(3) The immunity of suckling piglets is determined according to the herd infection in the farm. Pigs that have not had a pseudorabies outbreak in this field or around them can be immunized with one killed vaccine after 30 days; if the outbreaks in this field or around them should be 19 days old or 23- One vaccination of the gene-deficient attenuated vaccine was inoculated at 25 days of age; pigs with frequent outbreaks should be nasally dripped with the gene-deficient attenuated vaccine at 3 days of age.
(4) Infected areas or severely affected pig farms: Conservation and fattening herds should be boosted once every three weeks after the first exemption.

This disease can cause abortion of pregnant sows, stillbirths, infertility of boars, massive deaths of newborn piglets, dyspnea and growth retardation of fattening pigs, etc. It is one of the major infectious diseases that endanger the global pig industry.
The Pseudorabies Test For Pig (Ab) kit provided by BALLYA can effectively detect whether pigs have swine pseudorabies. This kit is not only simple to operate, but also has a short test time and high accuracy. Allow the veterinarian to respond accordingly.

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