Kanamycin belongs to the aminoglycoside antibiotics, and its treatment targets are sensitive bacteria, such as Escherichia coli, Salmonella, Proteus, etc. At present, the main dosage forms are kanamycin sulfate eye drops and amikacin sulfate injection. The former is mainly used to treat conjunctivitis, blepharitis, and keratitis caused by sensitive bacteria.
Through the modification of the chemical structure of kanamycin, the antibacterial spectrum can be more extensive, so the latter is mainly used to treat bacteremia, sepsis, lower respiratory tract infections, bone and joint infections, abdominal cavity infections, and complicated urinary tract infections caused by sensitive bacteria.
Since various sensitive bacteria are prone to resistance to kanamycin, the kanamycin on the market is no longer directly used in clinics, but processed to form kanamycin mono-sulfate or amikacin sulfate used clinically.
Kanamycin is a protein biosynthesis inhibitor, which can be taken orally or intravenously. It can effectively treat diseases caused by a variety of bacterial infections. Kanamycin is mainly used to treat intestinal infections and can reduce the effect of intestinal bacteria producing ammonia.
It has a strong antibacterial effect on Gram-negative bacteria such as Escherichia coli, Salmonella, Pneumoniae, Proteus, Pasteurella, etc. It is also effective against Staphylococcus aureus, Mycobacterium tuberculosis, and mycoplasma. But it has no effect on Pseudomonas aeruginosa, anaerobic bacteria, and other Gram-positive bacteria except Staphylococcus aureus.
It is also mainly used for respiratory and urinary tract infections and sepsis, mastitis caused by most gram-negative bacteria and some drug-resistant Staphylococcus aureus, orally for intestinal infections such as pullorum, typhoid, paratyphoid, fowl cholera, livestock Poultry colibacillosis, etc., chronic respiratory diseases of chickens, swine asthma and atrophic rhinitis and red neck disease of soft-shelled turtles.
For patients with renal insufficiency and hearing impairment, the use of kanamycin may cause gastrointestinal discomfort, including nausea, vomiting, loss of appetite, abdominal distension, diarrhea and other symptoms. Occasionally, patients may also experience allergic reactions such as skin rash and itching.
In severe cases, shock and respiratory failure may occur. Therefore, the patient must consult a doctor before using the drug. If an adverse reaction occurs, the drug should be stopped immediately.
The Hazards of Kanamycin
Since it was discovered in the 20th century that adding penicillin fermentation residues to feed animals can greatly increase the growth rate of livestock and poultry, the promotion effect of antibiotics on animal growth and its economic benefits have been fully verified.
Therefore, antibiotics have been widely used as feed additives for livestock and poultry. At the same time, antibiotics are also used in large quantities for the treatment of animal diseases by oral or injection, which has played a positive role in promoting the feed industry and its development. However, the residues and hazards of antibiotics in food, especially meat and its products, are becoming increasingly apparent.
Some antibiotics remaining in food can be destroyed by heating, but stable antibiotics, such as streptomycin and neomycin, cannot be destroyed by cooking. After people consume foods with excessive antibiotic residues for a long time, the antibiotic residues can be transferred to the human body and cause harm.
Antibiotic drugs have been detected in domestic and exported fish, shrimp, poultry, rabbit meat and dairy products produced in China, especially in milk and poultry, which has severely restricted the quality of animal-derived food in China.
Features of Kanamycin Test
1. 7min reading results
2. Detection limits respond to EU and US FDA norms
3. Neither professionals nor equipment required
4. Easy to operate and read
Detection Method of Kanamycin Test
Kanamycin Test, based on colloidal gold competition method, is used for testing Kanamycin residues in milk sample and meets EU MRL. This kit can be applied for on-site rapid testing by various departments.
Samples of Kanamycin Test
Samples include: raw milk, milk powder, pasteurized milk.
Detection Limit of Kanamycin Test
The LOD may change according to requirement or specimen's difference, please refer to kit instruction for further details.
Importance of Kanamycin Test
Kanamycin Test can help manufacturers, regulatory agencies, and the public monitor product quality and help humans protect their health.