Lincomycin, a drug, acts on the 50S subunit of the ribosome of sensitive bacteria to prevent the elongation of the peptide chain, thereby inhibiting the protein synthesis of bacteria and cells.
It is mainly used for the treatment of infections caused by Gram-positive bacteria and anaerobic bacteria in livestock and poultry veterinary. Its commercial qualified original drug is a white crystalline powder with a special smell, and its 10% aqueous solution has a pH of 3.0-5.5; it is common for oral administration in livestock and poultry. The commonly used preparation is 10% lincomycin hydrochloride soluble powder.
Lincomycin acts on the 50S subunit of the ribosome of sensitive bacteria to prevent the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells. Lincomycin is generally a bacteriostatic agent, but at high concentrations, it also has a bactericidal effect on highly sensitive bacteria.
The main antibacterial spectrum of lincomycin is gram-positive bacteria and some anaerobic bacteria. Gram-positive bacteria include some staphylococci and streptococci, so lincomycin can be used clinically to treat these sensitive bacteria.
These infections can occur in the skin and soft tissues, manifested as furuncle, carbuncle, erysipelas, and cellulitis; or occur in the respiratory tract, manifested as tonsillitis, pharyngitis, bronchitis, pneumonia, and lung abscess; or also occur in the female reproductive system, manifested as ovarian abscess, fallopian tube abscess, pelvic inflammatory disease; or occur in the abdominal cavity, manifested as abdominal abscess, peritonitis, liver abscess.
Lincomycin hydrochloride is used to treat gram-positive bacterial infections in pigs and chickens, such as swine dysentery, chicken necrotizing enteritis, etc., and can also be used in Mycoplasma infection in pigs and chickens.
Lincomycin, just like all other antibiotics, its residue will bring hidden dangers to human health. For example, milk that people often drink contains many kinds of antibiotic residues.
Antibiotics can promote the production of livestock and poultry, kill or inhibit harmful microorganisms in the animals (especially in the digestive tract), and adjust the microecological balance of the gastrointestinal tract of the animals, thereby improving animal health, promoting animal growth. But adding antibiotics to feed can easily cause residues in milk. This is also a very important cause of antibiotic residues in milk.
Some dairy farms use appliances that are in direct contact with milk. The milking appliances used by sick cows suffering from mastitis are directly used for milking healthy cows without strict cleaning and disinfection. In this way, the residual antibiotics in the milk of the former will cause antibiotic contamination to the milk of the latter.
Some dairy farms and dairy farmers do not have the technology and ability to store milk. In order to prevent the increase of bacteria in the milk and the rancidity of the milk, some drugs such as antibiotics are usually added to the milk. This is also the source of the antibiotics in the milk.
Long-term intake of milk with excessive antibiotic residues can cause cumulative poisoning; such as long-term intake of aminoglycosides can cause nephrotoxicity and ototoxicity. Many antibiotics, such as penicillin, cephalosporin, tetracycline, sulfonamides, etc., are antigenic and can cause allergic reactions.
There are a few antibiotics that have teratogenic, mutagenic, and carcinogenic effects. If you drink milk with residual antibiotics for a long time, it will cause serious harm to human health, especially for children and fetuses.
Features of Lincomycin Test
1. 7min reading results
2. Detection limits respond to EU and US FDA norms
3. Neither professionals nor equipment required
4. Easy to operate and read
Detection Method of Lincomycin Test
Lincomycin Test, based on colloidal gold competition method, is used for testing Lincomycin residues in milk sample and meets EU MRL. This kit can be applied for on-site rapid testing by various departments.
Samples for Lincomycin Test
Samples include: raw milk, milk powder, pasteurized milk.
Detection Limit of Lincomycin Test
The LOD may change according to requirement or specimen's difference, please refer to kit instruction for further details.
Importance of Lincomycin Test
Lincomycin Test can help manufacturers, regulatory agencies, and the public monitor product quality and help humans protect their health.