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BALLYA Sildenafil Test

ballya-test-kitBALLYA Sildenafil Test

What is BALLYA Sildenafil Test?

BALLYA Sildenafil Test is manufactured by BALLYA, it’s rapid test for detection the content of sildenafil in grains, food and seafood, especially in grains and food. Lateral flow assay test base on the gold immunochromatography assay technology.
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What is Sildenafil?

The pharmacological effects of sildenafil

Sildenafil is a selective inhibitor of cyclic guanosine phosphate (cGMP) specific type 5 phosphodiesterase (PDE5), and is an oral drug for the treatment of ED.

Sildenafil has no direct relaxation effect on the isolated human sponge, but it can enhance the effect of nitric oxide by inhibiting the decomposition of cGMP by PDE5 in the sponge. When sexual stimulation causes local nitric oxide release, sildenafil inhibits PDE5, increases cGMP levels in the cavernous body, relaxes the smooth muscle of the cavernous body, and blood flows into the cavernous body.

What is Sildenafil used for?

Sildenafil is an oral drug for the treatment of male erectile dysfunction. It was when Pfizer Pharmaceuticals of the United States developed a 5-phosphodiesterase inhibitor for the treatment of cardiovascular disease and accidentally discovered that this drug can improve the sexual life of patients.

In March 1998, the U.S. Food and Drug Administration approved a prescription drug for the treatment of male erectile dysfunction, and became the first oral drug specifically for the treatment of male erectile dysfunction in clinical practice.

What is the harm of Sildenafil?

Side effects of sildenafil

Common adverse reactions include headache, dizziness, facial flushing, indigestion, nasal congestion, and visual abnormalities. This abnormality may manifest as abnormal blue/green color discrimination, increased light perception, or blurred vision.

More serious adverse reactions also include: decreased supine blood pressure and decreased cardiac output. In addition, clinical studies have shown that having sex after taking sildenafil increases the risk of heart abnormalities, including symptoms such as angina, dizziness, and nausea, and it may cause sudden cardiac death.

Drug interactions of sildenafil

(1) When combined with CYP450 3A4 enzyme inhibitors (such as ketoconazole, itraconazole, erythromycin) and CYP450 non-specific inhibitors (such as cimetidine), the AUC of sildenafil increases and The clearance rate is reduced.

(2) When combined with HIV protease inhibitors [such as saquinavir, ritonavir (Ritonavir)], the cmax and AUC of sildenafil are increased, while saquinavir and ritonavir are drugs at steady state Kinetics is not affected.

(3) Combined use with loop diuretics, potassium-sparing diuretics and non-selective beta blockers can increase the AUC of the active metabolite of sildenafil (N-desmethylsildenafil) by 62 % And 102%, but this effect has no clinical significance.

(4) Co-administration with CYP4503A4 inducers (such as rifampicin) may reduce sildenafil plasma levels.

(5) When combined with CYP450 2C9 inhibitors (such as tolbutamide, warfarin), no obvious interaction was seen.

(6) With CYP450 2D6 enzyme inhibitors (such as selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazides and thiazide diuretics, angiotensin converting enzyme inhibitors, calcium channels Combination of blockers, etc. has no effect on the pharmacokinetics of sildenafil.
Note: The above content is for reference only! Please use this additive under the guidance of an expert!

What specimen can be detected by BALLYA Sildenafil Test?

Specimen include: all kinds of grains, food and medicine. Widely used in feed industry and food processing industry.
You can choose the right products according to your needs.

Significance of testing Sildenafil

To protect the animal have health grain, food, seafood and medicine, avoid contaminated food. The excess sildenafil is harmful for animal being, can’t take too much in the body.

Component of BALLYA Sildenafil Test?

BALLYA Sildenafil Test, 25 cassettes
Sample Buffer, 1 vial
Mini Pipette (optional)
Disposable micropipette tips (optional)
Kit Instruction, 1pcs
Sildenafil Test

How to use BALLYA Sildenafil Test?

1. Take some grain or food specimen
2. Add the supernatant to cassette
3. Wait for 15 minutes to result
4. The details of operation, refer to the kit instruction

Limitations of BALLYA Sildenafil Test?

BALLYA Sildenafil Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.

Conclusion

BALLYA Sildenafil Test is suitable for the detection of sildenafil residues in grain, food and seafood. Simple operation, high accuracy and short detection time are the characteristics of this product.

It can be widely used in food and drug administration, health departments, higher education institutions, scientific research institutes, agricultural departments, animal husbandry and veterinarians, breeding farms, slaughterhouses, food and meat products deep processing enterprises, inspection and quarantine departments and other units.

Where to buy BALLYA Sildenafil Test?

Get a free quote now and enjoy a 10% discount!

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