Trypsin inhibitor (TI) is a protein and a type of serine protease inhibitor (serpin) that reduces the biological activity of trypsin by controlling the activation and catalytic reactions of proteins.
The mechanism of Trypsin inhibitor
It has the effect of inhibiting the activity of trypsin in the small intestine, so it will hinder the digestion, absorption and utilization of protein in food after eating, and its toxicity can cause pancreatico-intestinal hypertrophy.
What is Trypsin Inhibitor used for?
Clinical application of Trypsin inhibitor
Trypsin inhibitor generally refers to aprotinin, which can inhibit trypsin and chymotrypsin, prevent the activation of other active proteases in the pancreas and the self-activation of trypsinogen.
Clinically, it can be used to prevent and treat acute pancreatitis, hemorrhage caused by fibrinolysis and diffuse intravascular coagulation. It can also be used for anti-shock therapy.
Direct injection into the abdominal cavity during abdominal surgery can also prevent intestinal adhesions.
For other types of trypsin inhibitors, it can also inhibit the activity of the corresponding protease, and can also be used to treat pancreatitis.
What are the Trypsin Inhibitor side effects?
It can inhibit the hydrolysis of feed by proteolytic enzymes in animal intestines, thereby hindering the digestion and utilization of feed protein by animals.
Adverse reactions of Trypsin Inhibitor
1 The injection rate is too fast, occasionally nausea, urticaria, fever, itching, and vascular pain. 2 Multiple injections may cause phlebitis, rapid pulse, cyanosis, hyperhidrosis, and difficulty breathing. 3 A small number of patients with allergies have allergic reactions after medication, and the medication should be stopped.
The hazards of Trypsin Inhibitor
It has a protective effect on the plant itself, can prevent the catabolism of the soybean grain itself to make the seed dormant, and has the function of resisting pests.
But for humans and animals, it is an anti-nutritional factor, which can slow down or stagnate animal growth, cause pancreatic hypertrophy, animal pancreatic hyperfunction, and lead to excessive pancreas secretion, resulting in essential amino acids (especially sulfur-containing amino acids). Intrinsic loss.
Note: The above content is for reference only! Please strictly follow the instructions for use, don’t abuse, don’t misuse!
What specimen can be detected by BALLYA Trypsin Inhibitor Test?
Specimen include: all kinds of feed, food and medicine. Widely used in feed industry and food processing industry. You can choose the right products according to your needs.
Significance of testing Trypsin Inhibitor
To protect the animal have health feed, food and medicine, avoid contaminated food. The excess trypsin inhibitor is harmful for animal being, can’t take too much in the body.
1. Take some feed or food specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Trypsin Inhibitor Test?
BALLYA Trypsin Inhibitor Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
In recent years, the impact of trypsin inhibitor on human health has received more and more attention, and the requirements for trypsin inhibitor testing have become higher and higher. Due to the complex composition of various samples, the determination of trypsin inhibitor is also more complicated. There are many methods for determining the content of trypsin inhibitor, but not every method is suitable.
BALLYA Trypsin Inhibitor Test is suitable for the detection of hormone residues, toxic and harmful substances and antibiotic residues in feed, food and medicine.
It can be widely used in food and drug administration, health departments, higher education institutions, scientific research institutes, agricultural departments, animal husbandry and veterinarians, breeding farms, slaughterhouses, food and meat products deep processing enterprises, inspection and quarantine departments and other units.