BALLYA Glibenclamide Test is manufactured by BALLYA, it’s rapid test for detection the content of glibenclamide in grains, food and seafood, especially in grains and food.
Lateral flow assay test base on the gold immunochromatography assay technology.
Glibenclamide is a sulfonylurea hypoglycemic agent. It inhibits liver glibenclamide and gluconeogenesis by increasing portal insulin levels or directly acting on the liver, reducing liver production and output glucose.
(1) To promote the secretion of insulin by pancreatic islet B cells, the prerequisite is that the pancreatic islet B cells have a certain function of synthesizing and secreting insulin;
(2) By increasing the level of portal vein insulin or directly acting on the liver, it inhibits liver glycogenolysis and gluconeogenesis, reducing liver production and glucose output;
(3) It may also increase the sensitivity of the extra-pancreatic tissues to insulin and the utilization of sugar (maybe mainly through the post-receptor effect). Therefore, the overall effect is to reduce fasting blood glucose and postprandial blood glucose.
Occasionally, abdominal or stomach discomfort, fever, skin allergies, hypoglycemia, should be reduced or stopped. There are gastrointestinal discomfort, fever, skin allergies, blood changes, etc. Improper use of the dose can cause severe hypoglycemia, especially when overdosed, there is a risk of death, and it should be corrected in time.
(1) Liver and kidney insufficiency, leukopenia,
allergic to sulfonamides, pregnant women and diabetes complicated with acidosis and acute infections should not be used.
(2) It can cause gastrointestinal reactions such as abdominal distension, abdominal pain, anorexia, and nausea. Allergies (erythema on the skin or urticaria), leukopenia, agranulocytosis, thrombocytopenia, hypoglycemia, etc. can also be seen. The drug should be stopped and treated immediately. Among them, hypoglycemia is more common.
(3) Glibenclamide and other sulfonylurea hypoglycemic agents cannot be combined with thiazide diuretics or glucocorticoids.
(4) Avoid taking it with anticoagulant drugs such as dicoumarin.
(5) When combined with phenylbutazone, it can increase the blood sugar lowering effect of this product, causing acute hypoglycemia.
(6) Combined use with sulfonamides can enhance the effect and toxicity of glibenclamide, so it is not suitable for combined use.
(7) Combined use with
chloramphenicol can also enhance the effects and side effects of this product. If the two drugs are used in combination, the dosage should be adjusted according to the patient's blood sugar level, otherwise it may cause hypoglycemic shock.
(8) Sulfonylureas can enhance the toxicity of ethanol, so alcohol should be abstained during treatment.
BALLYA Glibenclamide Test is suitable for the detection of glibenclamide residues in grain, food and seafood. Simple operation, high accuracy and short detection time are the characteristics of this product.
It can be widely used in food and drug administration, health departments, higher education institutions, scientific research institutes, agricultural departments, animal husbandry and veterinarians, breeding farms, slaughterhouses, food and meat products deep processing enterprises, inspection and quarantine departments and other units.
