BALLYA Histamine Test is manufactured by BALLYA, it’s rapid test for detection the content of histamine in grains, food and seafood, especially in grains and food. Lateral flow assay test base on the gold immunochromatography assay technology.
Histamine is an active amine compound. As a chemical conductive substance in the body, it can cause many cells to react, including allergies, inflammatory reactions and gastric acid secretion, and can also affect brain nerve conduction.
In the body, histamine is decarboxylated from histidine. It may be a neurotransmitter in the central nervous system of mammals.
Pharmacological effects of histamine
Pharmacological effects can be divided into three subtypes: H1, H2, H3. H1 effect: Exciting bronchi, gastrointestinal tract, uterine smooth muscle, expanding skin blood vessels, increasing capillary permeability, slowing down the conduction of atrial and atrioventricular nodes, and enhancing contractility.
H2 effect: stimulate gastric juice secretion, expand blood vessels, excite the heart (positive muscle strength and positive frequency effect).
H3 effect: It exists in the central and peripheral nerve endings, and it negatively regulates the synthesis and release of histamine.
What is Histamine used for?
Histamine is a self-active substance widely present in human tissues. It is produced by decarboxylation of histidine in the body, and has the functions of promoting capillary vasodilation and gastric juice secretion.
It is usually present in the granules of mast cells and basophils in the form of inactive binding, and is more abundant in skin, bronchial mucosa, intestinal mucosa and nervous system.
When the body is subjected to physical and chemical stimulation or an allergic reaction, these cells can cause degranulation of these cells, leading to the release of histamine and binding to histamine receptors to produce biological effects.
This can cause inflammation and allergic diseases, which can cause bronchoconstriction and mucus secretion in patients. After patients are exposed to allergens, increased levels of histamine can be seen in serum and bronchoalveolar lavage fluid.
Indications for histamine
1. It is mainly used for the examination of gastric secretion function to identify whether patients with gastric cancer and pernicious anemia have true gastric acid deficiency. At present, pentapeptide gastric acid hormone is often used instead of gastric stimulating hormone, but this product has been used less frequently.
2. Auxiliary diagnosis of leprosy.
3. It is also used clinically for desensitization, that is, the use of small doses of histamine for repeated incremental injections can improve the tolerance of patients to histamine. This method is used clinically to treat patients with unknown causes of allergies after specific examinations. Certain therapeutic effect.
What is the Histamine side effects?
This product injection may cause allergic reactions. If anaphylactic shock occurs, it can be rescued with adrenaline.
Histamine poisoning mainly occurs in coastal areas and areas where there is a habit of eating seafood.
When the fish body is not fresh or spoiled, bacteria decompose the histidine in the fish body into histamine, which increases the histamine content, which can cause allergic food poisoning after ingestion.
The clinical manifestations of poisoning are acute onset, mild symptoms and quick recovery. The onset usually occurs 0.5 to 1 hour after eating.
The main manifestations are: flushing, dizziness, headache, palpitation, rapid pulse, chest tightness and shortness of breath. Some patients may have blurred vision, face swelling, lip edema, numbness of mouth, tongue and limbs, nausea, vomiting, abdominal pain, urticaria, body flushing, etc.
Note: The above content is for reference only! Please use this drug under the guidance of an expert!
What specimen can be detected by BALLYA Histamine Test?
Specimen include: all kinds of grains, food and medicine. Widely used in feed industry and food processing industry. You can choose the right products according to your needs.
Significance of testing Histamine
To protect the animal have health grain, food, seafood and medicine, avoid contaminated food. The excess histamine is harmful for animal being, can’t take too much in the body.
1. Take some grain or food specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Histamine Test?
BALLYA Histamine Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
BALLYA Histamine Test is suitable for the detection of histamine residues in grain, food and seafood. Simple operation, high accuracy and short detection time are the characteristics of this product.
It can be widely used in food and drug administration, health departments, higher education institutions, scientific research institutes, agricultural departments, animal husbandry and veterinarians, breeding farms, slaughterhouses, food and meat products deep processing enterprises, inspection and quarantine departments and other units.