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Quinolones Erythromycin Test For Egg

beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Quinolones Erythromycin Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Quinolones and Erythromycin

About quinolones

Quinolones definition

Quinolones (4-quinolones), also known as pyruvates or pyridone acids, are synthetic antibacterial drugs containing the basic structure of 4-quinolones. Quinolones target bacterial deoxyribonucleic acid (DNA), hindering DNA gyrase, further causing irreversible damage to bacterial DNA, and achieving antibacterial effects.

Quinolones drugs

The first-generation quinolones only have antibacterial effects on Escherichia coli, Shigella, Klebsiella, and a few-Proteus. Specific varieties are Nalidixic acid and Piromidic acid, etc., which are rarely used because of poor efficacy.

The second-generation quinolones have expanded their antibacterial spectrum, and have certain antibacterial effects against Enterobacter, Citrobacter, Pseudomonas aeruginosa, and Serratia. Pipemidic acid is the main domestic variety. In addition, there are Cinoxacin and Miloxacin, which are produced abroad.

The antibacterial spectrum of the third-generation quinolones has been further expanded. It also has antibacterial effects on gram-positive bacteria such as staphylococcus, and further strengthens antibacterial effects on some gram-negative bacteria. In this class of drugs, norfloxacin has been produced in China. Ofloxacin, Perfloxacin, Enoxacin, Ciprofloxacin, etc. are still available. This generation of drugs have fluorine atoms in the molecules. Therefore, called fluoroquinolone.

The fourth-generation quinolones are structurally modified compared to the previous three-generation drugs. The introduction of 8-methoxy group in the structure helps to strengthen the anti-anaerobic bacteria activity, while the azadioxane structure at the C-7 position strengthens the anti-gram positive Bacteria activity and maintain the original activity against Gram-negative bacteria, adverse reactions are smaller, but the price is more expensive.

Quinolone and fluoroquinolone

Quinolone antibiotics include fluoroquinolone antibiotics.

About erythromycin

Erythromycin definition

Erythromycin is a class of antibacterial drugs with antibacterial effects. It is an antibiotic belonging to the class of macrolides. It is mainly used for a variety of infections, including respiratory infections, skin infections, as well as early syphilis, urogenital infections, oral Infection, etc. Its antibacterial spectrum is actually similar to penicillin. It has a strong inhibitory effect on Gram-positive bacteria like Staphylococcus, Streptococcus pyogenes, and Streptococcus pneumoniae. Bacillus also has a considerable inhibitory effect.

Is erythromycin a macrolide

Yes, erythromycin is an alkaline antibiotic produced by Streptomyces erythreus and belongs to macrolides.

How erythromycin works

Its mechanism of action is to penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor site ("P" position), blocking the transfer of ribonucleic acid (tRNA) binding to the "P" position. Blocking the displacement of the polypeptide chain from the accepting position ("A" position) to the "P" position inhibits bacterial protein synthesis, thereby playing an antibacterial effect.

Erythromycin ophthalmic ointment

As an antibiotic ointment, erythromycin eye ointment was first used to treat trachoma, conjunctivitis, blepharitis, and external eye infections. There are other uses for erythromycin eye ointment.
1. Slight trauma: erythromycin ointment can be used for minor bruises, scratches, or other traumas. The general usage is to clean and disinfect the affected area, and then apply the appropriate amount of ointment to the affected area twice a day.
2. Mild burns: For small burns and scalds, first rinse the wound with cold water, then apply a thin layer of erythromycin ointment to the surface.
3. Mosquito bites: When the mosquito bites are serious, the bitten parts should be cleaned and disinfected in time, and the appropriate amount of this ointment should be applied and applied twice a day for 5-7 days.
4. Nosebleed: Apply erythromycin ointment to the nasal septum in an appropriate amount, 4-5 times a day. It can disinfect and soften the nasal cavity, moisturize the nasal mucosa, improve the internal environment of the nasal cavity, and prevent bleeding again. Do not apply too much to prevent the ointment from flowing back into the inlet.
5. angular cheilitis: angular cheilitis is mostly caused by infection, more common in preschool children. For bacterial angular cheilitis, apply a small amount of erythromycin ointment while taking vitamin B2.

Erythromycin dose

1. (1) ① Common oral dosage: 1 ~ 2g per day, taken in 3 ~ 4 times. ② Legionnaires' disease: The daily dose can be increased to 2 ~ 4g, taken in 4 times. (2) Local administration: Treat trachoma, conjunctivitis, keratitis, apply an appropriate amount of ointment to the eyelid, several times a day. (3) Dose for renal insufficiency: patients with renal impairment generally do not need to reduce the dosage.
2. Children: (1) Oral administration: 30 to 50 mg / kg daily, taken in 3 to 4 times. (2) Local administration: trachoma, conjunctivitis, keratitis, apply an appropriate amount of ointment to the eyelid several times a day.
3. Intravenous infusion: (1) Adult: ① General dosage: 1 ~ 2g per day, divided into 2 ~ 4 times. ② Legionnaires' disease: 3 to 4g per day, divided into 4 doses. The high dose cannot exceed 4g. (2) Children: 20 to 40 mg / kg per day, divided into 2 to 4 times.

Erythromycin contraindications

Erythromycin can penetrate the placental barrier and enter breast milk, pregnant women and nursing women should be used with caution. Those who are allergic to macrolides.

Erythromycin poisoning

1. Common adverse reactions are gastrointestinal reactions, nausea, vomiting, stomach pain, diarrhea, mouth and tongue pain, loss of appetite, etc. The incidence is related to the dose. Can induce pseudomembranous enteritis.
2. Allergic reactions: various rashes, drug fever, eosinophilia, etc. There have been reports of 1 case of allergic purpura and renal failure. Esterified erythromycin can cause bile accumulating liver damage.
3. The application of high-dose erythromycin can occasionally cause tinnitus and temporary hearing impairment.
4. Intravenous infusion medication can easily cause phlebitis.

Erythromycin poisoning treatment

1. Stop the drug when a toxic reaction occurs, and intravenous fluids promote excretion.
2. When severe jaundice occurs, glucocorticoid therapy is given.
3. When an allergic reaction occurs, anti-allergic treatment is given.

Summary

As antibiotics, Quinolones and erythromycin are often used as veterinary drugs to treat poultry diseases and to promote the growth and production of poultry. This has led to the residue of Quinolones or erythromycin in many chicken and eggs.
Quinolones and erythromycin test for egg is essential, and Ballya has specifically studied this situation and has developed a rapid test kit for Quinolones and Erythromycin. Yes, people in need can quickly and easily detect Quinolones and Erythromycinin eggs. The test results comply with EU standards. Not only the operation is simple, but also the time is short and the precision is high. Ballya will continue to conduct more research in this area.

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