What is Betalactam Tetracycline Sulfonamides Combo Test?
Tri Sensor Kit, rapid to detect beta lactams, tetracycline antibiotics and sulfonamides residues in egg and egg product by using colloidal gold immune-chromatography technology. As soon as 7-10 minutes to results.
β-lactam antibiotics refer to a large class of antibiotics with a β-lactam ring in the chemical structure, including penicillin and its derivatives, cephalosporins, monoamide rings, carbapenem and penicillin enzymes Inhibitors and other atypical β-lactam antibiotics such as newly developed cephamycins, thiomycins, monocyclic β-lactams, etc.
Basically all antibiotics including β-lactam core in their molecular structure belong to β-lactam antibiotics. It is the most widely used class of existing antibiotics.
2. Mechanism of action
The action mechanisms of various β-lactam antibiotics are similar, and they can inhibit cell wall mucopeptide synthase, that is, penicillin binding protein, thereby hindering cell wall mucopeptide synthesis, causing bacterial cell wall defect and bacterial swelling and cracking.
In addition, lethal effects on bacteria should include triggering the autolytic enzyme activity of the bacteria, and mutant strains lacking autolytic enzyme show drug resistance. Mammals have no cell wall and are not affected by β-lactam drugs. Therefore, this class of drugs has a selective bactericidal effect on bacteria and is less toxic to the host.
These include penicillin and its derivatives, cephalosporins, monoamide rings, carbapenems and penicillinase inhibitors, as well as newly developed cephamycins, thiomycins, monocyclic β- Lactam and other atypical β-lactam antibiotics.
β-lactam antibiotics are available in both injection and oral dosage forms, and are easy to use. It is widely used clinically, and bacterial infections in various parts of the human body can be treated almost, including bacterial infections of the respiratory system, digestive system, urinary system, reproductive system, facial features, cerebral nervous system, skin and soft tissues, bones and joints.
What are tetracyclines?
Tetracyclines are a class of broad-spectrum antibiotics produced by actinomycetes, including chlortetracycline, oxytetracycline, tetracycline, and the semi-synthetic derivatives metoxycycline The structure of cyclamycin, dimethylaminotetracycline, etc. contains naphthylphenyl skeleton.
2. Mechanism of action
The mechanism of action is that the drug can specifically bind to the A position of the 30S subunit of the bacterial ribosome, preventing the connection of the aminoacyl-tRNA at this position, thereby inhibiting the growth of the peptide chain and affecting bacterial protein synthesis.
Tetracycline antibiotics mainly include chlortetracycline, oxytetracycline, and tetracycline. Tetracycline antibiotics have a common chemical structure. Both chlortetracycline and oxytetracycline are derivatives of tetracycline, the former is chloretracyelin, the latter is oxyeracyein, and the tetracycline family are both acid-base amphoteric compounds.
For the diagnosis of malignant tumors; for various cysts; for the treatment of intractable pleural effusion and effusion; for the treatment of bronchopleural fistula; for the treatment of axillary odor; for the treatment of internal hemorrhoids; for the treatment of rosacea; bullous pemphigoid; for the treatment of acute acne Pityriasis lichenoid; treatment of acne; for the clinical treatment of rickettsial disease, chlamydia disease, mycoplasma disease, spirochete disease.
What are sulfonamides?
Sulfonamide, also known as diaminosulfonyl, thioamide. The chemical formula SO2 (NH2) 2. The molecular weight is 96.11. Orthogonal plate-like crystals can absorb dry ammonia gas at room temperature to form a colorless ammonia complex, which is stable in acidic, neutral and alkaline aqueous solutions.
2. Mechanism of action
Bacteria cannot directly use the folic acid in their growing environment, but use the p-aminobenzoic acid and dihydroiodine tincture in the environment. Dihydrofolate of glutamic acid in the enzyme body synthesizes dihydrofolate under the catalysis of synthetase. Under the action of dihydrofolate reductase, tetrahydrofolate is formed. As a coenzyme of one-carbon unit transfer enzyme, tetrahydrofolate participates in the synthesis and synthesis of synthase precursors, and synthase is an essential component for bacterial growth and reproduction.
The chemical structure of sulfa drugs is similar to that of PABA. It can compete with PABA for dihydrofolate synthase, which affects the synthesis of dihydrofolate, thus inhibiting the growth and reproduction of bacteria. Because sulfa drugs can only inhibit without sterilization, they eliminate the body Pathogens ultimately depend on the body's defense capabilities.
A. Sulfa drugs that are easily absorbed by the intestinal tract. Mainly used for systemic infections, such as sepsis, urinary tract infection, typhoid fever, osteomyelitis, etc. According to the length of drug action time, it is divided into short-acting, medium-acting and long-acting categories. The short-acting type absorbs quickly in the intestine and excretes quickly. The half-life is 5 to 6 hours and needs to be taken 4 times a day. The half-life of the medium-acting type is 10 to 24 hours and 2 times a day. More than hours.
B. Sulfa drugs that are difficult to absorb in the intestine. Can maintain a high drug concentration in the intestine. Mainly used for intestinal infections such as dysentery and enteritis.
C. Topical sulfa drugs. Mainly used for burn infection, suppurative wound infection, ophthalmological diseases, etc.
A. epidemic cerebrospinal meningitis;
B. urinary tract infection;
C. respiratory tract and pharyngeal infection;
D. intestinal infection;
E. local infection.
The hazards of Betalactam, Tetracycline and Sulfonamides
If the egg containing antibiotics is eaten for a long time, the sensitive bacteria in the body will be killed or suppressed, but the resistant bacteria will multiply, which will break the original balance and cause long-term diarrhea or malnutrition. In severe cases, it can also cause resistant bacteria. infection.
Regularly eating egg containing antibiotics is equivalent to long-term absorption of low-dose antibiotics. On the one hand, it can cause some pathogens in the body to gradually become resistant to multiple antibiotics; on the other hand, antibiotics can be selected in dairy farms. Drug-resistant bacteria may enter the human body through food, and then transfer drug-resistant factors to sensitive bacteria in the human body.
Features of Betalactams Tetracyclines Sulfonamides Test
1. 8min reading results
2. Detection limits respond to EU and US FDA norms
3. Single test for every target sample
4. Neither professionals nor equipment required
5. Eyes interpretation or quantitative measurement, suitable for lab and field use
6. Room temperature storage
7. Non-toxic and harmless
Detection Method of Betalactams Tetracyclines Sulfonamides Test
The Betalactams Tetracyclines Sulfonamides Test is a colloidal gold immune-chromatography assay that detects Beta-lactams, Tetracycline and Sulfonamides in egg and egg products and meets EU MRL. This kit can be applied for on-site rapid testing by various departments.
Samples for Betalactams Tetracyclines Sulfonamides Test
Samples include: egg and egg products.
Detection Limit of Betalactams Tetracyclines Sulfonamides Test
The LOD may change according to requirement or specimen's difference, please refer to kit instruction for further details.
Importance of Betalactams Tetracyclines Sulfonamides Test
Betalactams Tetracyclines Sulfonamides Test can help manufacturers, regulatory agencies, and the public oversee product quality and help humans protect their health.
Components of Betalactams Tetracyclines Sulfonamides Test
1. Micro-Well Reagent: 8 tests/tube, 12 tubes/box
2. Test Strip: 8pcs/tube, 96pcs/box
3. Manual Instruction: 1pc
Materials for Betalactams Tetracyclines Sulfonamides Test
1. Sample Tube
2. Pipette & Pipette Tip
How to use Betalactams Tetracyclines Sulfonamides Test?
1. Add 200ul test solution into a well, then pipet up and down for 10 times to completely mix the sample with the reagent in the well.
2. Then incubate for 3min.
3. Insert the test strip into the micro-well with the sample pad fully dipped.
4. After 5 minutes, read the results.
When antibiotics were first used on humans, we regarded them as "elixir". As the problem of antibiotic abuse continues to worsen, their resistance has also brought huge harm to humans.
Therefore, in daily life, we should avoid food with antibiotic residues. The first step to self-help: we need to detect antibiotic residues.
How to order a Betalactams Tetracyclines Sulfonamides Test?
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