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Tetracyclines Test For Egg

beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Tetracyclines Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: What is tetracyclines?

About tetracyclines

Tetracycline is the most basic compound in the tetracycline family of antibiotics. It and its salts are yellow or light yellow crystals. It is extremely stable in the dry state. Except for chlortetracycline, the aqueous solutions of other tetracycline families are quite stable. The tetracycline family is soluble in dilute acids, dilute alkalis, etc., slightly soluble in water and lower alcohols, but insoluble in ethers and petroleum ethers.

Tetracycline classification

Tetracycline antibiotics mainly include chlortetracycline, oxytetracycline, and tetracycline. Tetracycline antibiotics have a common chemical structure. Both chlortetracycline and oxytetracycline are derivatives of tetracycline. The former is chloretracyelin and the latter is oxyeracyein.

Tetracyclines doxycycline

Tetracycline and Doxycycline are components of a broad-spectrum antibiotic called tetracycline antibiotics. All antibiotics in this class of drugs are derived from the same four-carbon ring basic structure. However, the specific ring structure of each drug is slightly different and should be recommended based on pharmacokinetics and bacterial resistance. Although doctors use these two drugs to treat many of the same infections, they have proven that each drug is often more effective in certain applications.

The main difference between tetracycline and doxycycline is the difference in pharmacokinetics. Pharmacokinetics refers to the body's response to specific drugs. This includes how the body disperses and metabolizes the drug, and even excludes it eventually. For example, the body tissues that are metabolized by tetracycline are different from doxycycline. The metabolic concentration of doxycycline reaches the highest in the eyes, while the essence of tetracycline is mainly in body fluids.

Tetracycline hydrochloride

Tetracycline hydrochloride is a broad-spectrum antibiotic, which has an inhibitory effect on most Gram-positive and negative bacteria, high-concentration bactericidal effect, and can inhibit Rickettsia, trachomavirus, etc. It has a good effect on Gram-negative bacteria. Its mechanism of action is mainly to prevent the binding of aminoacyl groups to ribonucleoprotein bodies, to prevent the growth of peptide chains and protein synthesis, thereby inhibiting the growth of bacteria. It also has a bactericidal effect at high concentrations.

How do tetracyclines work

Tetracyclines mechanism of action

Tetracycline antibiotics form a reversible conjugate with the 30S subunit of the bacterial inner ribosome to inhibit protein synthesis and play an antibacterial effect. When the antibiotic concentration is low, this reversible competitive binding will also be useless, and bacterial protein synthesis will continue. Tetracycline can also inhibit mitochondrial protein synthesis by binding to the mitochondrial 70S subunit. The binding ability of tetracycline to the 80S subunit of eukaryotic cells is relatively weak, so the ability to inhibit protein synthesis in eukaryotic cells is also weak.

Tetracyclines uses

Tetracycline for fish

Low concentration is bacteriostatic, and high concentration is sterilization. It has no effect on viruses, fungi and Pseudomonas aeruginosa. The effect on Gram-positive bacteria is close to that of penicillins, and the effect on Gram-negative bacteria is similar to that of chloramphenicol. It is used to prevent and treat bacterial diseases such as fish enteritis, red skin and rotten gills.

Tetracycline for dogs

Canine enteritis medication. Tetracycline (10-20 mg / kg, twice a day for 1 to 2 weeks) can obtain satisfactory results. In some cases, metronidazole (10-20 mg / kg, twice a day, continued medication for 1 to 2 weeks) is better because it also has the effect of suppressing obligate anaerobic bacteria.

Tetracycline for chickens

Tetracycline drugs can prevent and treat various diseases of poultry, such as typhoid fever, dysentery, cholera, infectious synovitis, infectious rhinitis, chronic respiratory disease, streptococcus disease, staphylococcus disease, listeriosis, spirochete disease and coccidiosis Wait. In addition, it also has the effect of reducing stress response, increasing egg production and increasing hatchability.

Tetracyclines list

There have been three generations of tetracycline antibiotics.
The first-generation products chlortetracycline, tetracycline and oxytetracycline are natural antibiotics, which are widely used because of their broad spectrum, ease of use, and economy. Later, it was found that the chemical structure of these antibiotics is not stable enough, and it is easy to produce drug resistance. Severe bacterial resistance has led to an urgent need to develop new tetracycline antibiotics.

Through extensive structural modification, the second generation semi-synthetic tetracycline antibiotics represented by doxycycline and minocycline were found. This type of antibiotics is more lipophilic and conducive to cell uptake, but in recent years its antibiotic-resistant strains have continued to appear, limiting its clinical application.

In 2005, the US Food and Drug Administration (FDA) approved the listing of tigecycline, which has a significant inhibitory effect on widely-resistant Staphylococcus aureus and vancomycin-resistant bacteria, and the glycyl ring represented by it The emergence of antibiotics marked the birth of the third generation of tetracycline.
Because the necessary pharmacophore of the third-generation tetracycline against drug-resistant bacteria is to have a variety of substituents on the D ring, such as glycyl, dimethylamino, and fluoro. It is very difficult to construct this kind of structure with the previous semi-synthetic method. It is necessary to develop a new and efficient total synthesis method to construct the D-ring multi-substituted tetracycline skeleton, which also marks the study of tetracycline from semi-synthesis into a new era of total synthesis.

Tetracyclines side effects

The first is the obvious gastrointestinal reaction. If you take oral tetracycline drugs, it will directly stimulate gastrointestinal function, causing gastrointestinal symptoms such as nausea, vomiting, abdominal pain, diarrhea, abdominal discomfort, indigestion, and loss of appetite. Symptoms such as ulcers of the esophagus, stomach ulcers, and bleeding may appear.
Second, there is a double infection, such as the frail elderly, because of the combined use of glucocorticoids and anti-tumor drugs, it will have a double infection.
Third, it will affect the growth of bones or teeth, so children should not use it as much as possible.
Fourth, there will be liver damage.
Fifth, there is nephrotoxicity.

Summary

Tetracyclines is a kind of antibiotic with strong action and broad antibacterial spectrum. It is currently an important medicine for preventing and curing livestock and poultry diseases in China. The residue in animal food has attracted attention. Tetracyclines test for egg is essential, and Ballya has specifically studied this situation and has developed a rapid test kit for tetracyclines. Yes, people in need can quickly and easily detect tetracyclines in eggs. The test results comply with EU standards. Not only the operation is simple, but also the time is short and the precision is high. Ballya will continue to conduct more research in this area.

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