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Betalactam Test For Egg

beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Betalactam Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: What is beta lactam?

Beta lactam

Beta lactam definition

Cyclic amides, the Greek letter used to indicate the number of rings: β-lactam (four-membered ring).

Beta lactam mechanism of action

The mechanisms of action of various β-lactam antibiotics are similar. They can inhibit cell wall mucin synthetase, penicillin binding proteins (PBPs), thereby hindering cell wall mucin synthesis and causing bacterial cell wall defects Body swelling and lysis. In addition, the lethal effect on bacteria should include triggering the bacteria's autolysin activity, and mutant strains lacking autolysin showed resistance.

Beta lactam ring

The Beta lactam ring is part of the core structure of several antibiotic families. The main families are penicillin, cephalosporins, carbapenems, and monobactams, so it is also called beta-lactam antibiotics. Almost all of these antibiotics work by inhibiting the biosynthesis of bacterial cell walls. This has a lethal effect on bacteria, although any given bacterial population will usually contain a subgroup that is resistant to beta-lactam antibiotics. The development of bacterial resistance is due to the expression of many genes.

Beta lactam classification

Beta lactam antibiotics

Beta-lactam antibiotics are a wide range of antibiotics, including penicillin and its derivatives, cephalosporins, monoamide rings, carbapenems and penicillin enzyme inhibitors. β-lactam antibiotics (β-lactams) refer to a large class of antibiotics with a β-lactam ring in the chemical structure. Basically, all antibiotics including β-lactam nucleus in their molecular structure belong to β-lactams Antibiotics, which are the most widely used types of existing antibiotics, including the most commonly used penicillins and cephalosporins in clinic, as well as newly developed cephamycins, thiomycins, monocyclic β-lactams, etc. Atypical β-lactam antibiotics. Such antibiotics have the advantages of strong bactericidal activity, low toxicity, wide indications and good clinical efficacy.

Beta lactam antibiotics list

Penicillins
Penicillin is also known as penicillin G and peillin G. Penicillin is a kind of antibiotic. It refers to a class of antibiotics containing penicillin in the molecule, which can destroy the cell wall of bacteria and play a bactericidal role during the reproduction period of bacterial cells. It is an antibiotic extracted from penicillium. Penicillin belongs to β-lactam antibiotics (β-lactams).

Cephalosporins
Cephalosporin antibiotics are widely used antibiotics. Cephalosporins are semi-synthetic antibiotics containing cephalosporins, which belong to β-lactam antibiotics and are derivatives of 7-aminocephalosporanic acid (7-ACA) in β-lactam antibiotics, so they have similar Sterilization mechanism.

Monoamide ring
Monocyclic beta-lactam antibiotics (monobactams) represent drugs including aztreonam and carumonan, which are narrow-spectrum antibiotics against aerobic gram-negative bacilli. Amidase stability and effect on negative bacilli including P. aeruginosa are similar to ceftazidime. Resistance to positive bacteria and anaerobic bacteria.

Carbapenems
Carbapenem antibiotics are the most atypical β-lactam antibiotics with the broadest antibacterial spectrum and strongest antibacterial activity. Because of their stability to β-lactamase and low toxicity, they have become the most important treatment for severe bacterial infection One of antibacterial drugs. Its structure is similar to the penicillin ring of penicillins.

Penicillinase inhibitors

And some other antibiotics, basically all antibiotics that include β-lactam core in their molecular structure belong to β-lactam antibiotics.

Beta lactam drugs

Beta-lactam drugs include the following:
1) Penicillins: such as penicillin G, amoxicillin, ampicillin, and piperacillin. Before using penicillin antibacterial drugs, you must ask in detail whether you have a history of penicillin allergies, other drug allergies, and allergic diseases. Skin test, the concentration of skin test solution is generally 500U / ml. Once anaphylactic shock occurs, 0.1% epinephrine 0.5-1ml should be injected subcutaneously immediately, and there is no improvement in clinical performance. Repeat it 3-5 minutes later, and cooperate with other symptomatic rescue measures.

2) Cephalosporins: According to the antibacterial spectrum, antibacterial activity, stability to β-lactamase and renal toxicity, it is divided into four generations. The first generation: cefalexin, cefazolin, cefradine, cefadroxil; the second generation: cefaclor, cefuroxime, cefprozil, cefotiam, etc. According to the drug package, decide whether to conduct a drug allergy test. Those who are allergic to cephalosporins and those with penicillin anaphylactic shock or immediate reaction history are prohibited from this class of drugs.

3) New β-lactams.

Beta lactamase

Beta-lactamase is a class of enzymes secreted by resistant bacteria against lactam antibiotics. It can be combined with beta-lactam ring to cleave beta-lactam ring and be destroyed, and lose antibacterial activity. It is the main reason for the resistance of these bacteria.

Beta lactamase inhibitor

β-Lactamase inhibitors (β-Lactamase inhibitors) are a new class of β-lactam drugs. Plasmid delivery produces β-lactamase, which causes the hydrolysis of some drugs β-lactam ring and inactivation. It is the main way for pathogens to resist some common β-lactam antibiotics (penicillins and cephalosporins).

Beta lactam side effects

Side effects of β-lactam antibiotics include: diarrhea, dizziness, rashes, urticaria, overlapping infections (including Candida) (Rossi, 2004). Occasionally β-lactam antibiotics can cause fever, vomiting, erythema, skin Inflammation, angioedema and pseudomembranous enteritis.
Beta-lactam antibiotics and beta-lactamase inhibitors are often painful and inflamed when injected at the same time.

Beta lactam allergy

About 10% of patients are allergic to beta-lactam antibiotics. Allergic reactions occur in about 0.01% of patients (Rossi, 2004). About 5-10% of patients are cross-sensitive to penicillin derivatives, cephalosporins, and carbapenem antibiotics.

Summary

The β-lactam antibiotics represented by penicillin and cephalosporin have the characteristics of high efficiency, high safety and broad-spectrum antibacterial. They occupy an extremely important clinical position in clinical practice. Today, it is still the antibiotic of choice for G + cocci infections. Beta-lactam antibiotics can be used as veterinary drugs in poultry farms, which may result in residual beta-lactam in poultry or eggs produced by poultry. Beta lactam test for egg is essential, and Ballya has specifically studied this situation and has developed a rapid test kit for beta-lactam antibiotics. Yes, people in need can quickly and easily detect beta-lactam antibiotics in eggs. The test results comply with EU standards. Not only the operation is simple, but also the time is short and the precision is high. Ballya will continue to conduct more research in this area.

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