BALLYA Clenbuterol Test is manufactured by BALLYA, it’s rapid test for detection clenbuterol residues in lamb and beef, especially in beef. Lateral flow assay test base on the gold immunochromatography assay technology.
Clenbuterol is a potent β2 receptor agonist. It is characterized by a small effective dose and long-lasting effect, and its bronchodilator effect is 100 times that of salbutamol. Clenbuterol was taken orally 30 μg three times a day in asthma patients, compared with 5 mg orally terbutaline 3 times a day. They have similar effects on increasing FEV1 and maximum expiratory flow rate (FEF) and reducing airway resistance. It can be seen that the asthma effect of oral clenbuterol is 170 times stronger than that of
How Clenbuterol uses for?
Is clenbuterol legal?
Clenbuterol, also known as asthma, is a beta-adrenergic agonist (abbreviated as beta-stimulant) and is often used in medicine to treat asthma. It has the effects of promoting animal growth, reducing fat content and increasing lean meat, so it is often used as a feed additive, commonly known as lean meat extract. Chemicalbook can form residues in animal tissues. Humans can cause poisoning after eating pork containing clenbuterol, and usually have symptoms such as muscle tremor, palpitations, nervousness, nausea, and dizziness. Chinese government banned clenbuterol hydrochloride as feed additive in 1997.
Clenbuterol for bodybuilding
It can be used as an additive in the feed to promote lean meat formation. However, the substance cannot be excreted. Therefore, if a person eats meat containing lean meat, the body cannot metabolize it, which eventually poisons the nervous tissue of the human body and causes great harm. A selective receptor agonist that can increase the body's heat consumption and thereby achieve fat reduction. Medically used to treat asthma. Therefore, Clenbuterol is banned in bodybuilding competitions.
What's Clenbuterol side effect?
Clenbuterol poisoning
In recent years, it has been found that adding clenbuterol to feed can promote animal growth and increase the lean meat ratio of livestock and poultry, so it is called lean meat essence. Poisoning can be caused by consuming the internal organs or meat of animals that contain residual lean meat.
Clenbuterol poisoning diagnosis
1. A history of excessive consumption of animal offal or meat with lean meat extract residues. 2. Clinically, β-receptor excitement is manifested by cardiovascular toxicity, which may include palpitations, tachycardia, hyperhidrosis, muscle tremor, muscle weakness; headache, nausea, and dyspnea; convulsions and hypertension may occur in severe cases Crisis. 3． Laboratory inspection (1) Electrolyte disorders such as low potassium and low magnesium. (2) Elevated blood sugar and myocardial enzymes. (3) ECG: tachycardia, atrial fibrillation, ST-T changes may occur in severe cases.
Clenbuterol poisoning Treatment
To prevent the drug from continuing to be absorbed, those who are poisoned should induce vomiting as soon as possible and lavage the stomach if necessary. Symptomatic treatment (1) Maintain water, electrolyte and acid-base balance. (2) Antihypertensive drugs can be used in patients with hypertension. (3) Symptoms can be applied to relieve symptoms in mild cases.
What's Clenbuterol hydrochloride?
Clenbuterol hydrochloride properties
Clenbuterol hydrochloride is chemically named α-[(tert-butylamino) methyl] -4-amino-3,5-dichlorobenzyl alcohol hydrochloride, with a molecular formula of C12H18CI2N2O • HCI and a molecular weight of 313.65. It is a white or similar white crystalline powder, odorless, bitter, soluble in water, ethanol, slightly soluble in acetone or chloroform, insoluble in ether, chemically stable, cannot be destroyed by ordinary methods, and heated to 172 °C to break down.
Clenbuterol hydrochloride mechanism of action
It binds to the β-adrenergic receptor to form an agonist receptor complex, which activates the G5 protein, and the alpha subunit of the G5 protein subsequently activates adenylate cyclase, the cyclic adenylate (cAMP) produced by the enzyme) Is an important intracellular messenger molecule. The mechanism by which cyclic adenosine (cAMP) produces an effect is through binding to the regulatory subunit of protein kinase k to release the catalytic subunit of the enzyme, which phosphorylates a series of intracellular proteins. Some of these proteins are enzymes that are activated when phosphorylated. Cyclic adenylate response element binding protein (CREB) is phosphorylated by protein kinase A, binds to the cAMP response element of a gene regulatory site, and activates the transcription of this gene. Phosphorylation enhances the transcriptional activity of CREB, which is also in breastfeeding in animal cells, β-adrenergic receptor agonists mediate the transcription of many genes, and the activities of other enzymes are inhibited during phosphorylation
Clenbuterol hydrochloride poisoning
Acute poisoning of clenbuterol hydrochloride is mainly due to the activation of β2 adrenergic receptors in the heart and skeletal muscle. If you take too much clenbuterol for a short period of time, it can cause acute poisoning. The clinical manifestations are heart palpitations, chest tightness, dizziness, headache, nausea and vomiting, sore neck and back muscles, and increased blood pressure. The electrocardiogram showed sinus tachycardia, paroxysmal supraventricular tachycardia, sinoatrial block, and premature beats. Laboratory tests include increased blood image, myocardial enzymes, elevated blood glucose, decreased blood potassium, increased creatinine, and increased urea nitrogen.
What specimen can be detected by BALLYA Clenbuterol Test?
Specimen include: lamb or beef, etc. Widely used in lamb industry and beef industry.
Significance of testing Clenbuterol
To protect human have health food and avoid contaminated food. The clenbuterol is harmful for human being, can not take too much in body.
1. Take lamb specimen, beef specimen and extrat supernatant 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Clenbuterol Test?
BALLYA Clenbuterol Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
Conclusion
Clenbuterol has been widely used as an anabolic hormone in various industries. The lamb breeding industry and beef cattle breeding industry deserves special attention. Lamb and beef provides people with rich nutrition, making it indispensable in daily life. The problem of clenbuterol hormone residues in lamb and beef has always plagued people, so it is necessary to detect lamb and beef in time. BALLYA Clenbuterol Test provided by BALLYA can effectively and quickly detect the presence of clenbuterol residues in pork and beef. Not only the operation is simple, the test time is short, but the tester can get the test result in the first time.
