The main adverse reactions of this class of drugs are: ① gastrointestinal reactions: nausea, vomiting, discomfort, pain, etc.; ② central reactions: headache, dizziness, poor sleep, etc., and can cause mental symptoms; ③ because this class of drugs can inhibit γ -The effect of aminobutyric acid (GABA
), so it can induce epilepsy, with caution in those with a history of epilepsy; ④ This class of drugs can affect cartilage development, pregnant women and minor children should be used with caution; ⑤ can produce crystalline urine, still in alkali Sexual urine is more likely to occur; ⑥ Large doses or long-term application of this class of drugs are likely to cause liver damage.
It is generally believed that quinolone drugs cannot be used by pregnant women and children, because the drug affects cartilage development; patients with epilepsy cannot use quinolone drugs because quinolone drugs can inhibit the aminobutyric acid. Patients with epilepsy can cause seizures; quinolone drugs can have side effects on the liver, so patients with poor liver function should not use them; patients with poor renal function should not use quinolone drugs, because this drug will cause urine crystallization, can cause alkaline uremia in patients.
The main allergic reactions of quinolone drugs are: local redness, swelling, rash, urticaria, and photosensitivity. Among allergic reactions, anaphylactic shock is most harmful to patients, and even causes death. The incidence of anaphylactic shock is low.