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Betalactams Tetracyclines Streptomycin Test For Egg

beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Betalactams Tetracyclines Streptomycin Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Betalactam, Tetracyclines and Streptomycin

Betalactam

β-lactam antibiotics (β-lactams) refer to a large class of antibiotics with a β-lactam ring in the chemical structure. Basically, all antibiotics including β-lactam nucleus in their molecular structure belong to β-lactams Antibiotics, which are the most widely used types of existing antibiotics, including the most commonly used penicillins and cephalosporins in clinic, as well as newly developed cephamycins, thiomycins, monocyclic β-lactams, etc. Atypical β-lactam antibiotics. Such antibiotics have the advantages of strong bactericidal activity, low toxicity, wide indications and good clinical efficacy.

Beta lactam antibiotics examples

Including: Penicillins, cephalosporins, atypical βzhidao-lactams, β-lactamase inhibitors β-lactam antibiotics classification
(1) Penicillins are divided into 5 categories according to antibacterial spectrum and drug resistance:
1. Narrow spectrum penicillins: penicillin G, penicillin V
2. Enzyme-resistant penicillins: methicillin, cloxacillin, flucloxacillin
3. Broad-spectrum penicillins: ampicillin, amoxicillin
4. Anti-Pseudomonas aeruginosa broad-spectrum penicillins: carbenicillin, piperacillin
5. Anti-G-bacteria penicillins: mecillin and pimecillin
(2) Cephalosporins are classified according to antibacterial spectrum, drug resistance and nephrotoxicity
1. The first generation of cephalosporins: cefradine, cefalexin
2. Second-generation cephalosporins: cefuroxime, cefaclor
3. The third generation cephalosporins: cefoperazone, cefotaxime, cefixime
4. The fourth generation cephalosporin: cefpirome
(3) Other

Tetracycline family

The tetracycline family is soluble in dilute acids, dilute alkalis, etc., slightly soluble in water and lower alcohols, but insoluble in ethers and petroleum ethers. Tetracycline antibiotics mainly include chlortetracycline, oxytetracycline, and tetracycline. Tetracycline antibiotics have a common chemical structure. Both chlortetracycline and oxytetracycline are derivatives of tetracycline, the former is chloretracyelin, the latter is oxyeracyein, and the tetracycline family are both acid-base amphoteric compounds.

Tetracycline hydrochloride

Tetracycline hydrochloride is a broad-spectrum antibiotic, which has an inhibitory effect on most Gram-positive and negative bacteria, high-concentration bactericidal effect, and can inhibit Rickettsia, trachomavirus, etc. It has a good effect on Gram-negative bacteria. Its mechanism of action is mainly to prevent the binding of aminoacyl groups to ribonucleoprotein bodies, to prevent the growth of peptide chains and protein synthesis, thereby inhibiting the growth of bacteria. It also has a bactericidal effect at high concentrations.

Streptomycin

Streptomycin antibiotic

Streptomycin is an aminoglycoside antibiotic. Its anti-tuberculosis special effect has created a new era of tuberculosis treatment.

Streptomycin structure

Streptomycin is a white amorphous powder with hygroscopicity. Easily soluble in water, insoluble in most organic solvents, unstable under strong acid and alkali conditions. The appearance of streptomycin sulfate preparation is yellow powder, density 0.38g / L, pH1.5 ~ 3.5, soluble in water, slightly acidic, stable under neutral and acidic conditions, and easy to fail under alkaline conditions.

Streptomycin mechanism of action

Streptomycin is an antibiotic extracted from the culture solution of Streptomyces griseus. It belongs to the basic compound of aminoglycoside, which is combined with Mycobacterium tuberculosis ribonucleoprotein protein and plays a role in interfering with the protein synthesis of Mycobacterium tuberculosis, thereby killing or inhibiting the growth of Mycobacterium tuberculosis.

Streptomyces bacteria

Streptomyces bacteria is the most advanced actinomycete. A family of actinomycetes.
There are well-developed branched hyphae, without hyphae, and differentiated into vegetative hyphae, aerial hyphae, and 65 spore hyphae. Spore filaments then form conidia. The morphology and color of spore filaments and spores vary from species to species, and are one of the main identification traits of species. More than a thousand species have been reported, mainly distributed in the soil.

Streptomycin uses

As a tuberculosis drug, although streptomycin has been in clinical use for more than half a century, it is still a first-line antituberculosis drug. It can also be used as a microbial source bactericide, which can effectively control plant bacterial diseases.

Streptomycin side effects

Allergic reactions: Both streptomycin and dihydrostreptomycin can combine with serum proteins to form a complete antigen, but the antibodies produced are different, so there is no cross-reaction. Dihydrostreptomycin can be used for those allergic to streptomycin.
Urinary system: Streptomycin can cause mild damage to the kidneys, patients may have proteinuria, tubular urine, etc., generally does not affect continued medication.
Other: There may be pain and swelling at the intramuscular injection site, which is generally very mild and does not last long.

Streptomycin toxicity

1) Acute toxic reaction: numbness, dizziness, deafness, etc. are more common, most of them appear within 10 days after medication, the shortest appear numbness within 20 minutes after injection, lasting 1 to 6 hours, and the most serious can continue for 24 hours without disappearing. There is also perioral numbness, dizziness, movement disorders, headache, fatigue, vomiting, facial flushing, and in severe cases, sweating, dyspnea, and cramps are not easy to distinguish from anaphylactic shock. However, acute reactions are more likely to accumulate or gradually worsen, and some cases only appear at the beginning of the injection and disappear later. The acute reaction of streptomycin is generally considered to be related to the impurities it contains.

2) Chronic toxic reactions: ① Eighth cranial nerve damage; a) Damage to the vestibular system of the ear, mainly manifested by dizziness, headache, and frequent finger errors. Movement ataxia and the like will occur later; b) Cochlear damage: generally occurs later, often after a few months of medication or after withdrawal. The main symptoms are tinnitus and deafness. ② Local irritation: intramuscular injection of local pain, swelling, sterile abscess, etc. Intrathecal injection can cause fever, paleness, agitation, dyspepsia, convulsions, shock, and severe cases can lead to death. ③Damage to the kidney: Streptomycin has mild damage to the kidney, manifested as proteinuria and tubular urine, and some of the renal function temporarily declines and can be recovered after drug withdrawal. Serious permanent kidney damage is rare. ④Inhibition of bone marrow: manifested as leukopenia, thrombocytopenia, aplastic anemia and cytopenia. Leukopenia is common, aplastic anemia and whole blood cell reduction are occasionally seen. ⑤ There are also hirsutism, conjunctivitis, arthralgia, myocarditis, and toxic encephalopathy.

Summary

As antibiotics, betalactam, tetracyclines and streptomycin are often used as veterinary drugs to treat poultry diseases and to promote the growth and production of poultry. This has led to the residue of betalactam, tetracyclines or streptomycin in many chicken and eggs.
Betalactam, tetracyclines and streptomycin test for egg is essential, and Ballya has specifically studied this situation and has developed a rapid test kit for sulfonamide. Yes, people in need can quickly and easily detect sulfonamide in eggs. The test results comply with EU standards. Not only the operation is simple, but also the time is short and the precision is high. Ballya will continue to conduct more research in this area.

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