Chlorogenic Acid is a kind of phenylpropanoid compound produced by the shikimic acid pathway during aerobic respiration of plants. It also has anti-HIV, anti-tumor cell, antibacterial, central excitement, choleretic, and anti-oxidant properties. Teratogenic, anti-allergic and regulating the activity of cytochrome P450 ligase.
Preparation method of chlorogenic acid
From (1S)-1-ethoxyformyloxy-3-cis-[3,4-dihydroxy-trans-cinnamoyloxy]-4’-trans-5’-trans-dihydroxycyclohexane- γ-methyl formate is hydrolyzed with barium hydroxide catalyzed in methanol or isolated from green coffee beans to obtain chlorogenic acid.
What is the use of Chlorogenic Acid?
Since chlorogenic acid has a special inhibitory effect on hyaluronic acid (HAase) and glucose-6-phosphatase (Gl-6-Pase), chlorogenic acid is effective in healing wounds, healthy and moist skin, lubricating joints, preventing inflammation, and The balance regulation of blood sugar in the body has certain curative effect.
Chlorogenic acid has a strong inhibitory and killing effect on many diseases and viruses. Chlorogenic acid has pharmacological effects such as lowering blood pressure, antibacterial, antiviral, anti-inflammatory, increasing white blood cells, preventing diabetes, significantly increasing gastrointestinal motility and promoting gastric juice secretion, and has obvious effects on acute throat inflammation.
Suppress mutation and anti-tumor
Modern pharmacological experiments have proved that Eucommia ulmoides chlorogenic acid has anti-cancer and anticancer effects. Polyphenols such as chlorogenic acid in vegetables and fruits can inhibit the mutagenicity of carcinogen aflatoxin B1 by inhibiting activating enzymes.
Chlorogenic acid can also achieve anti-cancer and anti-cancer effects by reducing the utilization of carcinogens and their transport in the liver. Chlorogenic acid has a significant inhibitory effect on colorectal cancer, liver cancer and laryngeal cancer, and is considered to be an effective chemical protective agent for cancer.
As a free radical scavenger and antioxidant, chlorogenic acid has been proved by numerous experiments. The biological activity of chlorogenic acid can protect the cardiovascular system.
In addition, isochlorogenic acid B has a strong inhibitory effect on the biosynthesis of thromboxane and endothelin damage induced by hydroperoxidation.
What are the side effects of Chlorogenic Acid?
Chlorogenic acid has a sensitizing effect on humans and can cause asthma, dermatitis and other allergic reactions, but no such reaction after oral administration, because chlorogenic acid can be converted into substances with no sensitizing activity by small intestinal secretions.
Although chlorogenic acid has many biological effects, it does not mean that the more chlorogenic acid dietary intake, the better. Studies have shown that long-term excessive intake of chlorogenic acid may cause an acute increase in plasma homocysteine, which is related to the occurrence of cardiovascular diseases.
Note: The above content is for reference only, please use this substance under the guidance of experts!
What specimen can be detected by BALLYA Chlorogenic Acid Test?
Specimen include: all kinds of grain. Widely used in grain and Chinese herbal medicine. You can choose the right products according to your needs.
Significance of testing Chlorogenic Acid
To protect the health tobacco, avoid contaminated tobacco. The excess Chlorogenic Acid is harmful for animal being, can’t take too much in the body.
1. Take some tobacco specimen 2. Add the supernatant to cassette 3. Wait for 15 minutes to result 4. The details of operation, refer to the kit instruction
Limitations of BALLYA Chlorogenic Acid Test?
BALLYA Chlorogenic Acid Test is a qualitative test kit. It’s only for screening purpose. If have positive cases or suspected case, maybe use other detection method to make a further detection, such as, ELISA, PCR, qPCR, etc.
BALLYA Chlorogenic Acid Test is suitable for the detection of Chlorogenic Acid residues in all kinds of tobaccos. Simple operation, high accuracy and short detection time are the characteristics of this product.
It can be widely used in food and drug administration, health departments, higher education institutions, scientific research institutes, agricultural departments, animal husbandry and veterinarians, breeding farms, slaughterhouses, food and meat products deep processing enterprises, inspection and quarantine departments and other units.