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Betalactams Cefalexin Test For Egg

beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Betalactams Cefalexin Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Beta lactam and Cefalexin

About beta lactam

β-lactam antibiotics (β-lactams) refer to a large class of antibiotics with a β-lactam ring in the chemical structure. Basically, all antibiotics including β-lactam nucleus in their molecular structure belong to β-lactam antibiotics, which is the most widely used class of existing antibiotics.

Beta lactam ring antibiotics

These include penicillin and its derivatives, cephalosporins, monoamide rings, carbapenems and penicillinase inhibitors, as well as newly developed cephamycins, thiomycins, monocyclic β-endo Amides and other atypical β-lactam antibiotics.

Beta lactam products

1) Penicillins: such as penicillin G, amoxicillin, ampicillin, and piperacillin. Before using penicillin antibacterial drugs, you must ask in detail whether you have a history of penicillin allergies, other drug allergies, and allergic diseases. Skin test, the concentration of skin test solution is generally 500U / ml. Once anaphylactic shock occurs, 0.1% epinephrine 0.5-1ml should be injected subcutaneously immediately, and there is no improvement in clinical performance. Repeat it 3-5 minutes later, and cooperate with other symptomatic rescue measures.

2) Cephalosporins: According to the antibacterial spectrum, antibacterial activity, stability to β-lactamase and renal toxicity, it is divided into four generations. The first generation: cefalexin, cefazolin, cefradine, cefadroxil; the second generation: cefaclor, cefuroxime, cefprozil, cefotiam, etc. According to the drug package, decide whether to conduct a drug allergy test. Those who are allergic to cephalosporins and those with penicillin anaphylactic shock or immediate reaction history are prohibited from this class of drugs.

3) New β-lactams.

Beta lactamase

Beta-lactamase is a class of enzymes secreted by resistant bacteria against lactam antibiotics. It can be combined with beta-lactam ring to cleave beta-lactam ring and be destroyed, and lose antibacterial activity. It is the main reason for the resistance of these bacteria.

Beta lactam resistance

The first method of resistance is to use an enzyme to hydrolyze the β-lactam ring. By producing enzymes such as β-lactamase, bacteria can unravel the β-lactam ring in antibiotics, making antibiotics ineffective. The genes for these enzymes may be on the bacterial chromosomes themselves, or they may be obtained by plasmid exchange. Its gene expression may begin after exposure to antibiotics. The production of β-lactamase by bacteria does not mean that the use of any β-lactam antibiotics is ineffective. Sometimes β-lactam antibiotics can be used simultaneously with β-lactamase inhibitors. However, you should think carefully before using β-lactam antibiotics against any bacteria suspected of producing β-lactamase. In particular, the use of β-lactam antibiotics may cause bacteria to produce β-lactamase. If the use of β-lactam antibiotics at the beginning of treatment leads to the production of β-lactamase, it will make it very difficult to use other β-lactam antibiotics thereafter.

The second resistance method changes the structure of the penicillin binding protein. β-lactam antibiotics do not bind strongly to these penicillin-binding proteins, so β-lactam antibiotics cannot destroy the bacterial cell wall. Methicillin-resistant Staphylococcus aureus uses this method to resist β-lactam antibiotics. This method of resistance also excludes the use of β-lactam antibiotics for treatment.

About cefalexin

Cephalexin antibiotic

Cephalexin belongs to β-lactam antibiotics and cephalosporins.

Cephalexin mechanism of action

Its mechanism of action is to inhibit the cell wall synthesis of bacterial dividing cells by binding to one or more penicillin-binding proteins (PBPs) (cephalexin mainly binds to PBP-3), thereby playing an antibacterial effect. The antibacterial spectrum of cephalexin is similar to cephalosporin, but its antibacterial activity is worse than the latter. In addition to Enterococcus and methicillin-resistant Staphylococcus, Gram-positive cocci are sensitive to cephalexin. Cefalexin has a good antibacterial effect against Neisseria, and has a low sensitivity to influenza bacilli. It has a certain antibacterial effect against some Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Salmonella, and other Enterobacter bacteria, Acinetobacter, Pseudomonas aeruginosa and Bacteroides fragilis are resistant to cephalexin.

Cephalexin is used for

Cephalexin indication

Broad-spectrum antibiotics. Mainly used for Gram positive and negative bacterial infections, such as: influenza, hemorrhagic septicemia, streptococcosis, swine erysipelas, anthrax, emphysema, malignant edema, actinomycosis, necrotizing bacillus disease, hook end Septicemic fever (41-43 °C) or persistent low temperature (below 37 °C) caused by spirochete disease, indigestion, drinking cold water, sleeplessness, cripple walking, blue ears, tearing, etc. At the same time, it is used to treat various inflammatory diseases, such as: infectious pleura pneumonia, pneumonia, atrophic rhinitis, blue ear disease, mastitis, hysteritis, stomatitis, urethritis and other cough and wheezing, difficulty breathing, low pregnancy, more stillbirths or death of piglets 7-10 days after birth, breast swelling, milk deterioration, decreased milk production, foot and mouth ulceration, salivation, sores and purulence.

Cefalexin side effects

1. Gastrointestinal reactions: nausea, vomiting, diarrhea and abdominal discomfort are more common gastrointestinal symptoms, occasionally pseudomembranous enteritis.
2. Nervous system reaction: A few patients may experience dizziness, diplopia, tinnitus, convulsions and other nervous system reactions.
3. Hepatotoxicity: A few patients may have transient liver dysfunction (temporal elevation of serum alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase) after administration.
4. Nephrotoxicity: A few patients may experience temporary increases in urea nitrogen, creatine, and creatinine, and occasional proteinuria and oliguria.
5. Blood system: Occasional drop in hemoglobin, thrombocytopenia, neutropenia, eosinophilia, etc. after medication.
6. Others: Long-term medication may cause microflora imbalance and double infection; vitamin K and vitamin B deficiency may also occur.

Allergic reaction to cephalexin

Allergic reactions such as rash, urticaria, erythema, and drug fever are more common, and occasionally anaphylactic shock.

Summary

As antibiotics, Beta lactam and cephalexin are often used as veterinary drugs to treat poultry diseases and to promote the growth and production of poultry. This has led to the residue of Beta lactam or cephalexin in many chicken and eggs.
Beta lactam and cephalexin test for egg is essential, and Ballya has specifically studied this situation and has developed a rapid test kit for sulfonamide. Yes, people in need can quickly and easily detect sulfonamide in eggs. The test results comply with EU standards. Not only the operation is simple, but also the time is short and the precision is high. Ballya will continue to conduct more research in this area.

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