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Backing Cards For Lateral Flow Assays

Aflatoxin-M1-Test-Kit

For lateral flow immunodiagnostic assay

Dimension:300x80mm, 300x60mm
Packing:Roll/Box
Applications: IVD, food safety diagnostics
backing-cards-lateral-flow-assays
Backing Cards For Lateral Flow Assays Development

Backing Rolls For Lateral Flow Assays
Backing cards for lateral flow rapid diagnostic test kit is usually made of PS or PVC materials with self-adhesive, with main features of good flatness, strong adhesive and ageing resistance.
Strong adhesive force
Compared to the common adhesive used on the market, our adhesive is a stronger type, so only small amount of adhesive needed--20g/square meters to get strong sticking force, whereas other backing card producers have to apply 35g/square meters on it. As a result, it will be significant lessen the cleaning time of the strip cutter and reduce the defects, then further benefit a smooth continuous large scale production, especially those engage a lot of automatic instruments. 

Backing Cards For Lateral Flow Assays 

Extreme low rate of cold-flow characteristic
It made the backing cards very stable performance with high resistance to ageing and heat. Suitable to stick non-backing & backing NC membrane and surfactant-treated glass fiber sample pad or conjugate pad, especially good for DOA test kit and food safety test kit.

backing-card-for-lateral-flow-assays-test
Materials: PVC
Features: Economic and widely used in IVD, food safety diagnostic, animal diseases diagnostic, etc.
Thickness(mm): 0.30/0.40/0.50/0.60
Adhesive: Self-adhesive
Color: White color popular
Dimension: 300x80mm, 300x70mm, 300x60mm are common
Format: by sheet or by roll
Die Cut Lines: Customized

Materials: PS
Features: Less Abrasion to Cutter Blade
Thickness(mm): 0.29/0.41
Adhesive: Self-adhesive
Color: White color popular
Dimension: 300x80mm, 300x70mm, 300x60mm are common
Format: by sheet or by roll
Die Cut Lines: Customized

Materials: PET
Features: Higher Heat Resistance
Thickness(mm): 0.30/0.35
Adhesive: Self-adhesive
Color: White color popular
Dimension: 300x80mm, 300x70mm, 300x60mm are common
Format: by sheet or by roll
Die Cut Lines: Customized

Application
conjugate-pad-and-absorbent-pad-backing-card
Used in food safety diagnostics: Milk Test Kit for detection of antibiotics residues in milk and powdered milk.

Hydrophilic Membrane for Blood Glucose Test
The basic structure of the blood glucose test strip consists of a PET substrate, a hydrophilic membrane, a glucose oxidase reaction zone, carbon and silver electrodes, etc. This hydrophilic membrane uses PET as main material of the substrate, and then compounded by a coating made from special formula and processing method. It features with good stability and reliability, resistant to scratch and heat, is an ideal material of the core carrier of blood glucose test strips. Thickness 0.1 mm, contact angle15°
Glucose Test Backing Cards
This backing cards for glucose test is made of PET material by special formulation and processing method. Features with stable quality with high resistance to heat and shrinkage, suitable for backing all kinds of glucose test kit.

About diabetes

What diabetes is?

Diabetes definition

Diabetes is a group of metabolic diseases characterized by high blood sugar. Hyperglycemia is caused by insufficient insulin secretion or impaired biological function or both. Long-term high blood sugar in diabetes can cause chronic damage and dysfunction of various tissues (especially eyes, kidneys, heart, blood vessels and nerves).

Diabetes causes

Usually, genetic factors and environmental factors have led to the occurrence of diabetes. Mainly due to decreased insulin secretion caused by islet cell dysfunction, or the body is not sensitive to insulin or both, and glucose in the blood cannot be effectively used and stored.

Diabetes early symptoms

Early diabetes actually refers to pre-diabetes. At this stage, there are usually no obvious symptoms of discomfort and clinical manifestations, mainly found by testing blood glucose.

How diabetes is diagnosed?

The diagnosis of diabetes is generally not difficult. The fasting blood glucose is greater than or equal to 7.0 mmol / L, and / or the blood glucose is greater than or equal to 11.1 mmol / L two hours after a meal. After diagnosing diabetes, type:

Type 1 diabetes
The age of onset is young, mostly <30 years old, the onset is sudden, polydipsia, polyuria and polyphagia are obvious symptoms, high blood sugar levels, many patients take ketoacidosis as the first symptom, serum insulin and C peptide levels are low, ICA, IAA Or GAD antibodies can be positive. Oral medication alone is ineffective and requires insulin therapy.

Type 2 diabetes
Common in middle-aged and elderly people, obesity has a high incidence rate, often accompanied by hypertension, dyslipidemia, arteriosclerosis and other diseases. The onset of the attack is asymptomatic, and there are no symptoms in the early stage, or only mild fatigue, thirst, and unclear increase in blood sugar. A glucose tolerance test is required to confirm the diagnosis. Serum insulin levels were normal or increased in the early stages and decreased in the late stages.

Diabetes blood sugar levels

The specific values are as follows: fasting blood glucose in normal people: 3.9 to 6.1 mmol / L, and the blood glucose at 2 hours after a meal is below 7.8 mmol / L. Diabetes can be diagnosed if fasting blood glucose ≥ 7.0 mmol / L and blood glucose ≥ 11.1 mmol / L 2 hours after a meal. For example, fasting blood glucose is 6.1-7.0 mmol / L, and 2-hour postprandial blood glucose is between 7.8 and 11.1 mmol / L. Impaired sugar regulation is the performance of early diabetes.

Diabetes types

Type 1 diabetes, type 2 diabetes, special types of diabetes and gestational diabetes.

Diabetes type 1

What diabetes type 1 

Type 1 diabetes, formerly known as insulin-dependent diabetes, occurs mostly in children and adolescents and can also occur at various ages. The onset is relatively rapid, there is absolutely insufficient insulin in the body, and it is prone to ketoacidosis. Insulin treatment must be used to obtain satisfactory results, otherwise it will be life-threatening.

Diabetes type 1 symptoms

The disease occurs in childhood or adolescence, which is the first feature. In fact, except for children, type 1 diabetes may occur at all ages in a lifetime, especially during menopause. The second characteristic of type 1 diabetes is that the onset is usually rapid and symptoms such as thirst, polydipsia, polyuria, polyphagia, fatigue and weight loss, and rapid weight loss are obvious. Some patients developed ketoacidosis for the first time. The third characteristic of type 1 diabetes is that it will eventually receive insulin therapy without exception, so type 1 diabetes was originally called insulin-dependent diabetes.

Diabetes type 1 test

Do antibody tests, namely insulin autoantibodies (IAA), islet cell antibodies (ICA), glutamate decarboxylase antibodies (GAD-Ab), these antibodies may be positive in patients with type 1 diabetes. The insulin and C-peptide levels of Peugeot islet function are very low.

Diabetes type 2

What diabetes type 2

Type 2 diabetes was originally called adult-onset diabetes, and most of it occurred after 35 to 40 years of age, accounting for more than 90% of diabetic patients.
Patients with type 2 diabetes have not completely lost their ability to produce insulin. Some patients even produce too much insulin, but the effect of insulin is poor. Therefore, insulin is relatively deficient in patients, and insulin secretion can be stimulated by certain oral drugs. However, some patients still require insulin therapy at a later stage.

Diabetes type 2 symptoms

There is often a family medical history; it can occur at any age and is more common in adults; most of them are insidious, with relatively mild symptoms, only mild fatigue, and thirst, and more than half of them have no symptoms. Some patients have chronic complications, comorbidities or physical examination.

Diabetes type 2 test

Type 2 diabetes is caused by the ineffective function of insulin (less binding to the receptor), so not only to check fasting blood glucose, but also to observe blood glucose 2 hours after a meal, especially for islet function tests.

Diabetes type 1 vs type 2

First of all, the main difference between the two is that the pathogenesis is different!
Type 1 diabetes: mainly due to the destruction of B cells, leading to an absolute lack of insulin, most of which are autoimmune diseases;
Type 2 diabetes: The pathogenesis of type 2 diabetes includes two aspects: islet function defect and insulin resistance.

Secondly, the patient's age, morphology, and clinical symptoms also differ from:
Type 1 diabetes: It occurs at a young age and occurs mostly in children and adolescents.
Type 2 diabetes: mostly develops after adulthood. Some of these patients are dominated by insulin resistance.

Finally, clinical treatment is different:
Type 1 diabetes: Under normal circumstances, type 1 diabetes can only effectively control high blood sugar to stabilize the disease by injecting insulin. Oral hypoglycemic drugs have no effect.
Type 2 diabetes: It is more effective to take dietary treatment and oral hypoglycemic drugs. Another part of patients with type 2 diabetes is mainly due to defects in insulin secretion.

Which diabetes is worse

Diabetes type 1 and type 2 mainly depends on whether they are dependent on insulin, dependent on type I, and independent on type II. Type I requires long-term use of insulin therapy, and those with mild II need not use insulin. In severe cases, insulin therapy is also required. Both type II and type I require strict dietary control. So relatively speaking, Type I is more troublesome than Type II.

Diabetes complications

Diabetes complications can be divided into two categories, acute and chronic, according to the rapidity of the onset of diabetes complications and pathological differences.
1. Causes of acute complications of diabetes
Including diabetic ketoacidosis, hyperglycemia and hyperosmolarity, lactic acidosis, etc. The main cause of the disease is due to severe lack of insulin activity and inappropriate increase of glycemic hormones, resulting in excessively high blood sugar, causing sugar, fat and protein Metabolic disorders, resulting in imbalance of body water, electrolytes and acid-base balance.

2. Causes of chronic complications of diabetes
Chronic complications are the main causes of diabetes disability and death, mainly including: ① complications of large blood vessels, such as cerebrovascular, cardiovascular and lower extremity blood vessel lesions. ②Microvascular complications, such as kidney disease and fundus disease. ③ Neuropathy, including the sensory nerves responsible for the senses, the motor nerves that control physical activity, and autonomic neuropathy that manages the internal organs, blood vessels and endocrine functions, etc.

Diabetes rash

This skin change occurs in front of the calf. At the beginning, it is a round or oval dark red papule with a diameter of only about 0.3 cm. Some of these papules are scattered and others are clustered together with dander on the surface. After the rash subsides, local atrophy or hyperpigmentation may appear on the skin.

Diabetes cure

There is currently no cure for diabetes, but diabetes can be controlled through a variety of treatments. It mainly includes 5 aspects: education of diabetic patients, self-monitoring blood glucose, diet therapy, exercise therapy and drug therapy.

Diabetes insulin

Insulin therapy
Insulin preparations include animal insulin, human insulin and insulin analogs. According to the time of action, it is divided into short-acting, medium-acting and long-acting insulin.

Type 1 diabetes requires treatment with insulin. The non-intensified patients were injected 2 to 3 times a day, and the intensive patients were injected 3 to 4 times a day, or treated with an insulin pump. Need to adjust the dose often.

Patients with type 2 diabetes who have failed oral hypoglycemic agents first adopt the combined treatment method. The original oral hypoglycemic agent dose is unchanged, and mid-acting insulin or long-acting insulin analogues are injected at 10:00 before bedtime, usually adjusted every 3 days 1 time, the purpose is to reduce the fasting blood glucose to 4.9 ~ 8.0 mmol / L. If it is ineffective, the oral hypoglycemic agent is stopped and insulin is injected twice a day instead.
The biggest adverse reaction of insulin therapy is hypoglycemia.

Diabetes prevention

1. Pay attention to diet
Improper diet may cause diabetes.
2. Pay attention to exercise
If exercise and sleep are not appropriate, it may also lead to diabetes. Do aerobic activities at least 3 times a week, no less than half an hour each time; every hour, you have to stand up and exercise.
3. Get enough sleep
You can also prevent diabetes after a good sleep, and sleep 7 hours a day is the healthiest. When sleeping less than 6 hours a day, the risk of developing diabetes will increase twice; sleeping more than 9 hours a day will increase the risk of developing diabetes by 3 times.
4. Control sugar intake
This is relatively speaking. Diabetics cannot eat sugar, which means that sucrose and glucose cannot be eaten directly in the daily diet. Fructose can be eaten. The decomposition of fructose does not require insulin. However, the main components of honey are fructose and glucose, so please treat honey with caution.

What diabetes can eat

1. Eat more high-fiber foods to promote sugar metabolism in the body. Such as corn, wheat, cabbage, leeks, legume products.
2. Eat more low-sugar vegetables, such as leeks, zucchini, winter melon, pumpkin, green vegetables, green peppers, eggplant, mulberry leaves.
3. Eat more foods containing calcium, calcium deficiency can promote the aggravation of diabetes. Such as shrimp skin, kelp, ribs, sesame paste, soybeans, milk, etc.
4. Eat more foods rich in selenium, such as fish, mushrooms, sesame, garlic, mustard, etc., can lower blood sugar and improve diabetes symptoms.
5. Eat more foods rich in vitamin B and vitamin C, make up these two elements, help to slow down the process of diabetes complications, such as fish, milk, cabbage, beans and greens, mustard, cabbage, green peppers, fresh dates.

Diabetes in children

Pediatric diabetes is an endocrine and metabolic disease caused by insufficient insulin secretion, mainly carbohydrate, protein and fat metabolism disorders, causing fasting and postprandial hyperglycemia and urine sugar.

Diabetes symptoms in children

The onset of diabetes in children is more rapid, and suddenly shows obvious polyuria, polydipsia, multiple meals, and weight loss. Referred to as "three more and one less". School-age children drink 3 to 4 liters or more of water per day, and often thirsty to drink at night. Stomach increase but weight loss. Young children often draw parents' attention with enuresis and weight loss. About half of children with diabetes in children have ketoacidosis as the first manifestation, and the younger the age, the more severe the symptoms of ketoacidosis.

Is diabetes genetic?

Type 1 or type 2 diabetes has obvious genetic heterogeneity. Diabetes has a family tendency, and 1/4 to 1/2 of patients have a family history of diabetes. Clinically there are at least more than 60 kinds of genetic syndromes that can be associated with diabetes.

Summary

Although type 1 and type 2 diabetes cannot be completely cured at present, since the discovery of medical insulin, diabetes has been well treated and controlled by using a combination of diet control and hypoglycemic drugs or insulin supplements. The quality of life of patients can be basically the same as that of healthy people, and we must be confident that with the advancement of science and technology, we will one day be completely cured.
BALLYA glucose backing card suitable for the rapid diabetes test kit, has a high performance.
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