Tetracycline was discovered in 1940. It was popular for a long time. The tetracycline uses are efficacious and extensive. Tetracycline antibiotics can produce antibacterial effects by preventing the elongation of sensitive bacteria peptide chains and protein synthesis. Tetracycline antibiotics have a broad antibacterial spectrum and have a strong effect on Gram-negative bacteria, Gram-positive bacteria, spirochetes, Chlamydia, Rickettsia, Mycoplasma, Actinomyces and Amoeba.
Tetracycline antibiotics for veterinary are broad-spectrum antibiotics with a naphthacene structure. They are mainly divided into natural and semi-synthetic types. They can be taken orally, with broad antibacterial spectrum, low toxicity, few allergies, and more severe drug resistance. They Inhibit the growth of bacteria, but the effect is weak (less than penicillin or streptomycin).
Tetracycline antibiotics for veterinary use mainly include oxytetracycline, tetracycline, chlortetracycline, doxycycline, minocycline, metomycin, etc., each of which has its own focus on the therapeutic effect, and different requirements for the dosage for different types of livestock. You should follow the doctor's advice or specific application in accordance with the requirements of the product instructions.
Although veterinary tetracycline antibiotics have a wide range of effects, you should pay attention to the application and dosage which should be performed in an appropriate amount and time. Because the toxic and side effects of this drug should also be taken into account.
The adverse reactions of tetracycline drugs include: mainly local irritation, double infection and damage to the liver, etc. Oral administration of antibiotic directly stimulates the mucosa of the digestive tract; after intramuscular injection, due to the strong acidity of its hydrochloride, it can cause local pain, inflammation and necrosis; after intravenous injection, it can cause phlebitis and thrombosis. Among these irritants, chlortetracycline is the strongest, followed by oxytetracycline, and tetracycline is the lightest.
A. Precautions for using tetracycline
B. Disinfection work
In addition to the treatment of diseases, the more important thing is the management of the environment, to fundamentally reduce the harmful effects of bacteria and germs. In the daily pig management, in order to effectively control the growth of bacteria and prevent infection, the pig farm must be strictly disinfected.
a. Daily disinfection
b. If there are pigs died from diseases
Tetracycline has great side effects on chickens. It not only stimulates the digestive tract and damages the liver, but also combines with metal ions such as calcium ions and magnesium ions in the digestive tract of chickens to form complexes and hinder calcium absorption. At the same time, chlortetracycline can also interact with the calcium ions in the plasma combine to form insoluble calcium salts, which makes the chicken body lack calcium, thus hindering the formation of eggshells, causing soft-shelled eggs, poor egg quality, and decreased chicken lay rate.
Therefore, when using tetracycline antibacterial drugs, you should avoid feeding soybeans, black soybeans, and feeding additives such as stone meal, bone meal, eggshell powder, and gypsum should not be used.
In rural areas, many chicken farmers often use oxytetracycline to prevent and control poultry diseases, or use it as a feed additive, but excessive use can cause poisoning. Therefore, chickens fed with oxytetracycline need to prevent drug poisoning. Chicken oxytetracycline poisoning is mostly chronic, mainly manifested as malaise and shrinkage of the head and neck, reduced food intake, increased water consumption, diarrhea, white stools with bloodshot eyes, dry feathers with no luster. The body of the chicken is gradually thinning, the keel is bent, and the legs are limp; the comb is atrophy, pale, and the skin is purple; the egg production of the hen decreases or stops production.
Oxytetracycline, as a medicine for preventing poultry diseases, has obvious effects on the prevention and treatment of intestinal bacterial infections. In addition, oxytetracycline is relatively inexpensive and easy to buy. Therefore, many chicken farmers like to use it as a drug additive to mix in feed. The short-term application effect of this method is obvious, with little side effects. However, long-term use of oxytetracycline to feed chickens can easily damage their livers, cause chicken ascites, even numerous deaths, and bring economic losses to chicken farmers.
Tetracycline, an antibiotic, is mainly used to treat cat and dog infections caused by susceptible bacteria. Other similar antibiotics include: oxytetracycline, doxycycline, and minocycline.
Because many bacteria are resistant to tetracycline, tetracycline has rarely been used in dogs and cats’ treatment. Currently, veterinarians will even recommend prescribing doxycycline or minocycline to pets.
Tetracycline inhibits the protein necessary for the formation of bacteria, resulting in slower growth and death of bacteria, so that normal white blood cells can kill the remaining bacteria.
Tetracycline is a prescription drug that can only be obtained from or prescribed by a veterinarian.
Tetracycline Uses for cats and dogs
Tetracycline uses are wide and profound, whether for breeding animals or pets, or we humans. While we benefit from these antibiotics, we are also threatened by them. Appropriate amount and non-dependence will be our principle of treating these antibiotics.
The use of antibiotics will cause pathogenic microorganisms to develop resistance, making the effective dose of antibiotics that can kill bacteria continue to increase. Long-term discharge of low-dose antibiotics into the environment will increase the resistance of sensitive bacteria. Moreover, resistance genes can expand and evolve in the environment, posing potential threats to the ecological environment and human health. In addition to causing bacterial resistance, antibiotics may also be toxic to other organisms.