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Sulfanilamide Test For Chicken liver(R&D)

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beta-lactams-Test-Kit

For chicken liver

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Sulfanilamide Test For Chicken liver

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Do you know sulfanilamide?

About sulfanilamide

Sulfonamide, molecular formula: C6H8N2O2S, white granule or powder crystal, odorless, slightly bitter taste. Slightly soluble in cold water, ethanol, methanol, ether and acetone, easily soluble in boiling water, glycerin, hydrochloric acid, potassium hydroxide and sodium hydroxide solutions, insoluble in chloroform, ether, benzene, petroleum ether. It can be prepared from acetanilide by chlorosulfonation, amination, hydrolysis, and neutralization.

Sulfanilamide structure

1. Molar refractive index: 42.80
2. Molar volume (cm3 / mol): 120.6
3. Isotonic specific volume (90.2K): 340.9
4. Surface tension (dyne / cm): 63.7
5. Polarizability (10-24cm3): 16.97

Sulfanilamide synthesis

It is made from acetanilide by chlorosulfonation, amination, hydrolysis and neutralization. Raw material consumption quota: acetanilide (99%) 1032 kg / t, chlorosulfonic acid (96%) 4521 kg / t, liquid ammonia (99.8%) 535 kg / t, liquid alkali (30%) 863 kg / t.

Sulfanilamide uses

1. Used for the determination of nitrite. Biochemical research. Organic Synthesis.
2. This product is an important intermediate for sulfonamides. This product has a strong antibacterial effect against hemolytic streptococcus, meningitis, and cocci, but due to its poor efficacy and high toxicity, it is rarely used internally. It can be used as a spreading agent or ointment to prevent wound infections, but it can cause allergic reactions. It is also rarely used. It is used as an intermediate for the synthesis of other sulfonamides. It is also used as a raw material for the synthesis of agricultural "Huangcaoling" abroad.
3. Used as analytical reagent, such as reagent for photometric determination of nitrite and sodium nitroferricyanide. Used in biochemical research, organic synthesis and pharmaceutical industry.
4. The main raw material for synthesizing sulfonamides, in addition to preparing crystalline sulfonamides for external use for anti-inflammatory, it can also synthesize other sulfonamides such as sulfamidam, sulfamethazine, sulfamethazine, etc.

Sulfanilamide drugs

Sulfonamides are inhibitors of folic acid synthesis and have been used because of their low cost and efficacy against infections by pathogens such as urinary tract and trachoma. Sulfa drugs have a similar structure to para-aminobenzoic acid (PABA), and can compete with PABA for dihydrofolate synthase, thus preventing the synthesis of bacterial dihydrofolate and inhibiting the growth and reproduction of bacteria. Sulfonamides are broad-spectrum antibacterial agents.

Sulfanilamide indication

1. Systemic infection
Oral sulfonamides can be used for meningitis, otitis media, and simple urinary tract infections, as well as for the treatment of inclusion body conjunctivitis, trachoma, nocardiasis, and toxoplasmosis. It can also be used for streptococcal infection and rheumatic fever relapse in those allergic to penicillin.
2. Intestinal infections
Treat chronic inflammatory bowel disease, such as Crohn's disease or ulcerative colitis.
3. Other
It is used for skin tissue burns and wound infections, but it can cause double infection of drug-resistant bacteria or fungi.

Sulfanilamide side effects

1. Blood system reaction
Hemolytic anemia may occur, which is prone to occur after applying sulfonamides in patients lacking glucose-6-phosphate dehydrogenase; granulocytopenia and thrombocytopenia can also be seen.
2. Liver damage
Jaundice, decreased liver function, and severe liver necrosis can occur in severe cases.
3. Urinary tract damage
More common crystal urine, pain, hematuria and so on. It can prevent urine PH value and drink more water.
4. Other
Occasionally nuclear jaundice, crystal urine, etc.

Sulfanilamide allergy

Common rashes, angioedema, and Sjoy-Joy syndrome.

Sulfanilamide elixir

Diethylene glycol is used instead of alcohol as a solvent to prepare an oral liquid preparation with color, fragrance and taste, called Sulfanilamide elixir.

Sulfanilamide tragedy

In 1937, HaroldWotkins, the chief pharmacist of an American company, used diethylene glycol instead of alcohol as a solvent to make it easy to take for children, and prepared an oral liquid preparation with full color, fragrance, and taste, called sulfonamide elixir. Animal experiments, after being put into production at Masson Gill Pharmaceuticals in Tennessee, all entered the market for the treatment of infectious diseases. At that time, US law allowed new drugs to enter the market without clinical trials. From September to October of this year, some places in the southern United States began to find a large increase in patients with renal failure, and a total of 358 patients were found, and 107 died (most of them children), becoming the most influential medicine of the last century One of the harmful events. In 1937, the "sulfonamide elixir incident" prompted the US Congress to pass the Food, Drugs, and Cosmetic Act (Food, Drugs, and Cosmetic Act, FDCA, 1938), which had a major impact on Western pharmacy.

Summary

As a veterinary drug, this product is absorbed orally quickly but not completely. It is widely distributed in animals and can enter tissues and body fluids well. Mainly excreted from urine in the form of original drugs. But it is inevitable that there will be residual drugs left in the body. This is likely to cause Sulfanilamide residues in chicken. It is necessary to detect Sulfanilamide in chicken liver.
The Sulfanilamide Test For Chicken liver kit provided by BALLYA can effectively and quickly detect whether chicken liver contain Sulfanilamide residues. Not only is the operation simple and the detection time is short.

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