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Pefloxacin Test For Egg(R&D)

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beta-lactams-Test-Kit

For all kinds of eggs

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Pefloxacin Test For Egg

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Do you know pefloxacin?

About pefloxacin

Pefloxacin structure

Density: 1.32 g / cm3
Boiling point: 529.1ºC at 760 mmHg
Flash point: 273.8ºC
Refractive index: 1.593
Vapor pressure: 5.05E-12mmHg at 25 °C

Pefloxacin generation

1. Norfloxacin is the raw material, and the product is obtained by methylation.
2. Start with the intermediate boron chelate in norfloxacin. The boron chelate compound, acetonitrile, N-methylpiperazine and triethylamine were mixed, and reacted at room temperature before refluxing. The solvent was distilled off, water was added, and concentrated hydrochloric acid was adjusted to pH = 3 before refluxing. Add activated carbon to decolorize and filter. The filtrate was basified to pH = 11, and then activated carbon was decolorized, filtered, and neutralized with 30% acetic acid to pH = 6.7-7.2, overnight in the refrigerator. Filtration, washing with water and drying to obtain off-white pefloxacin with a yield of 82% and a melting point of 270-272 °C. Pefloxacin is dissolved in absolute ethanol, and methanesulfonic acid is added dropwise at 60-70 °C to react. After cooling to 15 °C, the precipitated crystals were filtered and recrystallized with 10 times ethanol to obtain pefloxacin mesylate.
3. The boron chelate, N-methylpiperazine and triethylamine can also be refluxed together. After alkaline hydrolysis, acidify to pH = 7.2 to obtain pefloxacin; add it to the aqueous solution of methanesulfonic acid, and the crude product obtained by the reaction is recrystallized with 85% ethanol to obtain pefloxacin mesylate.

Pefloxacin mechanism of action

Its sterilization mechanism is to inhibit the activity of DNA gyrase, thereby inhibiting the replication of bacterial DNA.

Pefloxacin uses

What does pefloxacin tablets treat?

Pefloxacin indication: Suitable for respiratory tract, urinary tract infections, gonorrhea, prostatitis, adult G-bacteria and staphylococcus serious infections caused by sensitive bacteria such as sepsis, endocarditis, bacterial meningitis, respiratory tract, urethra, kidney, otolaryngology infections, Gynecological diseases, abdominal, hepatobiliary, osteoarthritis and skin infections.

Pefloxacin dosage

Oral, 0.4g once, twice a day. The first dose can be doubled. Intravenous drip 0.4g once, twice a day. Dissolved in isotonic glucose injection. The infusion should not be too fast, drip after one hour. Adults and intravenous doses are 400 mg each time, once every 12h, the dose of urinary tract infections and other lighter infections should be reduced. Each time 400 mg of the product is intravenously infused, it needs to be diluted with 250ml of 5% glucose solution and then slowly dropped in the dark for at least 1h. It cannot be diluted with physiological saline or other chlorine-containing solutions to prevent precipitation. For patients with ascites and jaundice, take the medicine every two days.

Pefloxacin products

Pefloxacin injection

Colorless or slightly yellow, yellowish green clear liquid.
Indications: Various infections caused by pefloxacin-sensitive bacteria: urinary tract infections; respiratory tract infections; ear, nose, and throat infections; gynecological and reproductive system infections; abdominal and liver and gallbladder infections; bone and joint infections; Skin infections; sepsis and endocarditis; meningitis.

Pefloxacin tablet

Pefloxacin tablets are fluoroquinolones, a new type of fluoroquinolone antibacterial drugs, against G- and G + bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter, Haemophilus, Neisser Staphylococcus and Staphylococcus (including methicillin-resistant strains) have a broad spectrum of activity. Its resistance to Staphylococcus aureus is similar to that of vancomycin, but its resistance to Pseudomonas aeruginosa is not as good as ciprofloxacin and cemetazidine, and it is resistant to some multivalent drug-resistant strains and methicillin Medicine bacteria are also effective.

Pefloxacin side effects

1. Gastrointestinal reactions such as nausea, vomiting, upper abdominal discomfort, diarrhea, and reduction.
2. Nervous system reactions such as dizziness, headache, restlessness, and insomnia. The incidence of such reactions is lower than that of digestive tract reactions.
3. Allergic reactions such as skin rash, itching of the skin, angioedema, photodermatitis, etc., may even cause anaphylactic shock.
4. A few patients may have muscle pain, weakness, joint swelling and pain, and palpitations.
5. Laboratory examination may occur transient leukopenia, mild increase in serum aminotransferase, blood urea nitrogen and creatinine, etc., also reversible.
The above-mentioned adverse reactions are mild and most patients can tolerate them. However, fluoroquinolones such as norfloxacin can cause serious adverse reactions, including:
1. Change of consciousness, cuffs, seizures.
2. Transient hallucinations, hallucinations, double vision, etc.
3. Crystallized urine occurs during large doses of medication.

Pefloxacin contraindications

Renal insufficiency is used with caution. The product does not need to be reduced when it is used in patients with mild renal impairment, but it is appropriate to use it with caution in patients with liver function impairment. The mechanism of action of fluoroquinolone drugs such as norfloxacin is to inhibit the synthesis of DNA, and the damage to cartilage is found in young mice. Therefore, such drugs should not be used in children and pregnant women. The drug can be secreted into the milk. Patients with pre-existing epilepsy and other central nervous system diseases should avoid the use of fluoroquinolones such as this product, because they are prone to severe central nervous system reactions. Patients with severe renal impairment should also avoid application, because adverse reactions such as convulsions can occur.

Summary

As a veterinary drug, this product is absorbed orally quickly but not completely. It is widely distributed in animals and can enter tissues and body fluids well. Mainly excreted from urine in the form of original drugs. But it is inevitable that there will be residual drugs left in the body. This is likely to cause pefloxacin residues in chicken or eggs. It is necessary to detect pefloxacin in eggs.
The Pefloxacin Test For Egg kit provided by BALLYA can effectively and quickly detect whether eggs contain pefloxacin residues. Not only is the operation simple and the detection time is short, it allows the tester to obtain the test results in the fsirst time.

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