Nitrofurantoin is an antibiotic.
It has antibacterial effect, especially sensitive to Escherichia coli, and then more sensitive to Aerobacter and Proteus. In addition, P. aeruginosa is usually resistant to this drug and has no effect.
Nitrofurantoin is mainly used clinically to treat infections caused by sensitive bacteria. For example, Escherichia coli, Enterococcus, Staphylococcus, this kind of infection caused by bacteria, especially for acute, simple lower urinary tract infection can also be used for the prevention of urinary tract infection.
Nitrofurantoin macrocrystal are synthetic chemicals with controlled crystal size. The macrocrystalline nitrofurantoin is a larger crystalline form of nitrofurantoin. Compared with nitrofurantoin, nitrofurantoin absorbs large crystals more slowly and excretes less. Blood concentrations at therapeutic doses are usually low. It is highly soluble in urine and may turn brown. Nitrofurantoin macrocrystal are an antibacterial agent for specific urinary tract infections.
Macrobid is the brand name for nitrofurantoin, an antibiotic used to treat or prevent urinary tract infections.