Osteomalacia ntawm cov nyuj mis nyuj yog cov khoom noj khoom haus ntev cov kab mob metabolic, uas yog tshwm sim los ntawm qhov tsis muaj calcium, phosphorus lossis qhov tsis tsim nyog sib piv ntawm ob qho khoom noj, ua rau muaj kev tsis sib xws ntawm cov tshuaj calcium thiab phosphorus metabolism thiab kev txiav txim siab pob txha. Cov chaw kho mob tseem ceeb yog lub plab zom mov tsis haum, cov pob txha mos, deformed cov leeg, cov ceg tsis txawv txav, thiab lameness. Yog tsis kho kom raug, nws yuav ua rau poob lossis tag nrho poob peev peev nyuj, uas yuav muaj kev cuam tshuam rau kev tsim nyuj thiab kev txhim kho. Tom ntej no, cia peb paub: etiology ntawm osteomalacia hauv nyuj nyuj, cov tsos mob ntawm osteomalacia hauv nyuj nyuj thiab tiv thaiv thiab ntsuas ntsuas.
Kev pub mis tsis txaus hauv calcium, phosphorus, thiab vitamin D. Feem ntau, cov mis nyuj siv 1.2g ntawm calcium thiab 0.8g ntawm phosphorus ib kg ntawm lactation. Noj 20 kg ntawm kev pub niam mis ua piv txwv, txhua hnub poob ntawm calcium thiab phosphorus vim lactation nce mus txog 24g thiab 16g, feem. Tsis tas li, qhov xav tau txhua hnub ntawm calcium thiab phosphorus rau kev tswj hwm lub cev kev ua haujlwm ntawm nyuj nyuj yog 20g thiab 15g. Raws li qhov tseeb tias cov mis nyuj muaj peev xwm nqus tau 22% - 55% ntawm cov calcium hauv pub, nyuj nyuj nrog 20 kg ntawm mis ib hnub yuav tsum nqus ntau dua 120 g ntawm calcium thiab 83 g ntawm phosphorus ib hnub. Yog tias cov ntsiab lus ntawm calcium thiab phosphorus hauv cov mis nyuj pub mis qis dua tus txheej txheem no, cov calcium thiab phosphorus khaws cia hauv lub cev pob txha yuav tau txav mus los txhawm rau tswj hwm lub cev kev ua haujlwm thiab kev pub mis rau lub cev, yog li ua rau muaj tus kab mob tshwm sim. Tsis tas li, yog tias kev noj zaub mov muaj cov vitamin D tsawg dua, nws yuav ua rau lub cev muaj peev xwm nqus tau calcium thiab phosphorus hauv kev noj haus, yog li ua rau tus kab mob.
Cov kev faib ua feem ntawm calcium thiab phosphorus hauv kev pub mis tsis tsim nyog. Rau cov neeg laus mis nyuj, 38% ntawm cov pob txha tshauv yog calcium, 17% yog phosphorus, uas yog, qhov sib piv ntawm calcium rau phosphorus yog 2: 1. Yog li, qhov sib piv ntawm calcium rau phosphorus hauv kev noj zaub mov yuav tsum ze rau qhov sib piv ntawm calcium rau phosphorus hauv pob txha, uas yog, los tswj nws ntawm 1-2: 1. Yog tias peb tsis xyuam xim rau kev npaj, uas ua rau muaj phosphorus ntau dhau, calcium tsawg dhau lossis ntau dhau calcium, phosphorus tsawg dhau, kuj tseem tuaj yeem ua rau tsis txaus calcium thiab phosphorus, yog li ua rau muaj kab mob.
Tej kab mob. Thaum nyuj muaj hyperparathyroidism, ntau cov ntsev calcium hauv cov pob txha yuav yaj thiab ua rau muaj kab mob. Nyuj nyuj raug kev txom nyem los ntawm mob plab thiab rog ua lub siab, uas tuaj yeem cuam tshuam rau kev ua kom cov vitamin D, yog li txwv tsis pub nqus cov calcium thiab phosphorus, thiab cuam tshuam rau cov txheej txheem osteogenesis, thiab tom qab ua rau muaj tus kab mob. Cov mis nyuj nyuj lub raum tsis ua haujlwm tuaj yeem ua kom cov calcium tawm ntawm lub raum, uas tuaj yeem ua rau tus kab mob. Nyuj nyuj raug kev txom nyem los ntawm kab mob plab zom mov, uas yuav cuam tshuam ncaj qha rau kev nqus cov calcium thiab phosphorus, thiab tom qab ntawd ua rau muaj kab mob.
Lwm yam. Cov noob caj noob ces thiab hnub nyoog tseem cuam tshuam rau calcium thiab phosphorus nqus hauv cov nyuj mis nyuj. Tsis tas li, tsis kub, siab kev pub mis ntom ntom, thiab cov cua tsis zoo yuav ua rau muaj kev hloov pauv ntawm cov calcium thiab phosphorus xav tau. Lub xub ntiag ntawm calcium thiab phosphorus antagonists lossis siab concentration ntawm fluoride hauv dej haus thiab pub tuaj yeem ua rau muaj kev cuam tshuam ntawm kev nqus cov calcium thiab cov pob txha metabolism tsis txawv txav.
Thaum pib, cov nyuj muaj mob tsuas yog ua rau lub plab zom mov tsis zoo, txo qis kev noj haus thiab haus dej, muaj lub siab tsis zoo, heterophilia, xws li noj cib, av thiab lwm yam. Cov quav yog nyias thiab qhuav, sib xyaw nrog cov khoom noj uas tsis tau zom zaub mov. Tom qab ntawd tsis kam sawv lossis nyuaj rau sawv, lub plab curled, nraub qaum, feem ntau dag rau hauv av, nrog rau a ceg tawv los yog ob peb nqua, thiab feem ntau yog metastatic. Thaum mob hnyav lossis hnyav, nws yooj yim nkees, nrog mob hnyav, thiab thaum kawg tuag tes tuag taw hauv av. Feem ntau ntawm lawv tsuas tuaj yeem tshem tawm vim tias lawv nquag poob lossis tawg thaum lub sijhawm tawm dag zog. Tsis tas li, lub cev kub, ua pa, thiab mem tes ntawm cov nyuj muaj mob tau zoo ib txwm nyob rau theem pib, tab sis lub plawv dhia nrawm dua nyob rau theem tom ntej, mus txog 70-80 ntaus/feeb, thiab lub plawv suab nrov. Tsis tas li, yog tias cov nyuj muaj mob pw hauv av tau ntev, lawv feem ntau yuav muaj teeb meem, xws li lub txaj pw, thiab kev kwv yees tsis zoo.
Kev kho tshuaj sab hnub poob. calcium carbonate, pob zeb hmoov lossis calcium citrate hmoov yuav tsum tau ntxiv rau kev noj haus ntawm cov nyuj mis nyuj kom ntseeg tau tias cov calcium thiab phosphorus noj txhua hnub thaum lub sijhawm qhuav mis nyuj tsawg kawg yog 55 g thiab 22 g. Hauv lub sijhawm pub niam mis, tus nqi ntawm calcium thiab phosphorus Fed tau txiav txim siab raws li tus nqi ntawm kev pub niam mis, uas feem ntau xav tau 2.5 g ntawm calcium thiab 1.8 g ntawm phosphorus ib kilogram ntawm mis. Cov nyuj uas muaj mob tuaj yeem txhaj tshuaj nrog 500-1000 ml 20% calcium gluconate txhaj lossis 100-200 ml 10% calcium chloride txhaj rau 3-5 hnub sib law rau ntxiv calcium. Hauv kev noj haus ntawm cov nyuj muaj mob, 30-100g sodium phosphate thiab 250g tricalcium phosphate tuaj yeem ntxiv, thiab 500 ml 20% sodium dihydrogen phosphate txhaj tuaj yeem txhaj tshuaj ib hnub ib zaug rau 3-5 hnub rau kev kho mob. Txhawm rau txhim kho kev nqus thiab siv cov calcium thiab phosphorus hauv txoj hnyuv, kev txhaj tshuaj ntawm 5-10mL vitamin AD txhaj lossis 5-20 mL vitamin D2 gelatinous calcium (vitamin D2 gelatinous calcium) txhaj tshuaj tuaj yeem txhaj ib zaug ib hnub ib zaug ntawm 3-5 hnub rau kev kho mob.