Trimethoprim Test

Cov Khoom Siv Ib Leeg, nrawm los tshuaj xyuas Trimethoprim seem hauv cov mis thiab cov khoom siv mis los ntawm kev siv colloidal kub tiv thaiv-chromatography thev naus laus zis. Sai li 7-10 feeb rau cov txiaj ntsig.

Cov khoom no yog me ntsis soluble hauv chloroform thiab ethanol thiab acetone, yuav luag tsis yaj hauv dej, yooj yim soluble hauv glacial acetic acid.

Trimethoprim yog tus tiv thaiv kab mob dihydro-folate reductase thiab yog sulfonamide synergist. Lub hauv paus ntsiab lus ntawm nws cov tshuaj tua kab mob yog los cuam tshuam nrog folic acid cov metabolism hauv cov kab mob. 

Lub hom phiaj tseem ceeb yog xaiv kom tsis txhob cuam tshuam kev ua haujlwm ntawm cov kab mob dihydrofolate reductase, yog li ntawd dihydrofolate tsis tuaj yeem txo qis rau tetrahydrofolate, yog li cuam tshuam kev loj hlob thiab tsim cov kab mob. 

Trimethoprim muaj cov tshuaj tua kab mob tiv thaiv kab mob gram-positive thiab gram-negative bacteria; ntxiv rau, trimethoprim kuj tseem muaj qee yam cuam tshuam rau kab mob malaria thiab qee yam hu ua fungi, xws li Nocardia, histoplasma, thiab cov poov xab. 

Ntawm cov kab mob gram-positive, Streptococcus pneumoniae yog rhiab rau trimethoprim. Ntawm cov kab mob gram-negative, Escherichia coli, Salmonella, Proteus mirabilis, Bacillus pneumoniae, Bacillus dysentery, Bacillus typhi, Bacillus pertussis, thiab lwm yam yog nkag siab rau trimethoprim. Trimethoprim tsis muaj cov tshuaj tua kab mob rau Pseudomonas aeruginosa, Meningococcus thiab Alcaligenes.

A. Trimethoprim tuaj yeem siv ib leeg los kho cov kab mob tso zis yooj yim thiab kab mob prostatitis los ntawm cov kab mob rhiab.

B. Trimethoprim thiab sulfamethoxazole lossis sulfadiazine tuaj yeem siv los kho tus mob sepsis, meningitis, otitis media, typhoid fever, Shigellosis (bacillary dysentery) los ntawm cov kab mob rhiab.

C. Trimethoprim ua ke nrog sulfa-2,6-dimethoxine kuj tseem tuaj yeem siv los kho tus mob malaria tiv taus chloroquine.

Cov kab mob tua kab mob ntawm trimethoprim zoo ib yam li sulfamethoxazole, thiab cov tshuaj tiv thaiv kab mob yog 20-100 zaug muaj zog dua li sulfamethoxazole. Trimethoprim yog tshuaj tua kab mob bacteriostatic thaum siv ib leeg, thiab nws zoo dua thaum siv ua ke nrog tshuaj sulfa, thiab tuaj yeem tua tau cov kab mob. Yog tias cov kab mob rhiab rau ob yam tshuaj no ib leeg, kev txwv qis hauv ib qho tshuaj tuaj yeem txo MIC ntawm lwm cov tshuaj ntau dua 4 txog 8 zaug. Tab sis cov txiaj ntsig sib xyaw ua ke sib txawv hauv cov kab mob sib txawv lossis kab mob.

Muaj qib siab ntawm kev sib koom ua ke ntawm Neisseria gonorrhea thiab Proteus. Feem ntau ntawm Staphylococcus, Streptococcus, Pneumococcus, thiab Influenza bacillus, kev sib koom tes tsuas yog 4-8 zaug. Qhov siab uas ua rau muaj kev sib koom ua ke zoo tshaj plaws yog kev sib koom tes ntawm MIC. Kuj tseem muaj qee yam kab mob uas cuam tshuam rau ob qho tshuaj, tab sis tsis tsim cov txiaj ntsig zoo sib xws. Piv txwv li, cov kab mob tiv taus cov tshuaj sulfa tsuas yog rhiab rau trimethoprim. Feem ntau hais lus, lawv tsis tuaj yeem tsim kev sib koom ua ke, uas tsuas yog sib npaug rau TMP ua ib leeg.

Piv txwv, yog tias cov tshuaj sulfa siab dua, kev sib koom tes tuaj yeem tshwm sim hauv vitro. Qhov no yog qhov tseem ceeb ntawm kev kho mob me me, vim tias cov tshuaj sulfa loj dhau tsis muaj kev nyab xeeb, tab sis nws yuav muaj txiaj ntsig zoo rau cov kab mob tso zis vim tias muaj cov tshuaj sulfa siab ntau hauv cov zis. Piv txwv li, Pseudomonas aeruginosa tiv taus nruab nrab cov tshuaj sulfa thiab tuaj yeem tsim cov tshuaj tiv thaiv kab mob ua ke thaum ua ke nrog trimethoprim. Kev tshawb fawb hauv tsev ua pov thawj tias trimethoprim muaj cov txiaj ntsig sib xyaw ntawm ntau yam tshuaj tua kab mob.

Piv txwv li, qhov sib txuam ua ke ntawm kev sib xyaw nrog tetracycline ntawm Staphylococcus aureus, Escherichia coli thiab Pseudomonas aeruginosa ntau dua li ua ke nrog sulfamethoxazole; rau tiv Staphylococcus aureus, trimethoprim tuaj yeem txhim kho penicillin thiab neopenicillin Ⅱ thiab erythromycin; rau Pseudomonas aeruginosa tuaj yeem txhim kho cov nyhuv ntawm gentamicin thiab kanamycin. Txawm li cas los xij, qee tus neeg xav tias trimethoprim yuav tsum tsis txhob sib xyaw nrog tetracycline, doxycycline, kanamycin lossis gentamicin, vim tias muaj tsawg tsawg hom kab mob uas ua rau muaj kev cuam tshuam. Cov ntaub ntawv txawv teb chaws hais tias trimethoprim muaj qhov cuam tshuam zoo sib xws ntawm Streptococcus pyogenes, Enterococcus, Proteus, Klebsiella, Escherichia coli thiab Pseudomonas aeruginosa.

Kev sim tsiaj kuj tseem tau lees paub tias nws tuaj yeem txhim kho kev muaj sia nyob ntawm cov nas mob. Cov kab mob tiv taus rifampicin lossis trimethoprim kuj tseem tuaj yeem sib koom ua ke. Qhov ib txwm muaj ntawm ob yam tshuaj tuaj yeem mus txog qib sib xyaw hauv tus neeg mob lub cev. Sulfonamides thiab polymyxin muaj cov txiaj ntsig sib xyaw ntawm cov kab mob tsis zoo. Trimethoprim tsis tshua pom muaj cov kab mob uas tsim tshuaj tiv thaiv kab mob thaum kho, tsuas yog li 10%. Qhov no yuav yog vim qhov tseeb tias TMP feem ntau siv ua ke nrog cov tshuaj sulfa, thiab cov kab mob uas ua rau muaj kev cuam tshuam rau ob yam tshuaj tsis tuaj yeem ua rau tsis muaj zog. 

Tab sis cov kab mob uas tsuas yog rhiab rau TMP yog nquag tsim kev tawm tsam. Nws kuj tau raug pov thawj hauv chav kuaj pom tias kev tiv thaiv ntawm cov kab mob tsis zoo rau TMP tau tsim sai, thiab nrog rau kev thov mus sij hawm ntev, kev tiv thaiv yuav nce ntxiv.

Sulfonamide antibacterial synergists yog hluavtaws diamino-pyrimidine tshuaj. Ditrimethoprim thiab trimethoprim yog ob qho uas feem ntau siv sulfonamide antibacterial synergists hauv Suav teb. Cov tshuaj no tuaj yeem txhim kho cov tshuaj sulfa thiab ntau yam tshuaj tua kab mob. 

Nws tau siv dav hauv kev tiv thaiv thiab kho kab mob ntawm cov tsiaj txhu thiab nqaij qaib thiab coccidiosis. Nrog rau kev siv tsis tsim nyog thiab txawm tias siv tshuaj sulfa hauv tsiaj kho tsiaj, cov khoom seem yuav zam tsis tau ntxiv. Tib neeg siv sijhawm ntev ntawm cov khoom noj tsiaj thiab cov khoom uas muaj ditrimethoprim lossis trimethoprim seem yuav ua rau muaj kev phom sij rau tib neeg kev noj qab haus huv.

Tshuaj tua kab mob thiab lawv cov txiaj ntsig tseem nyob hauv dej thiab zaub mov, thiab lawv tau khaws cia hauv cov zaub mov ntev ntev, ua rau muaj kev cuam tshuam rau tib neeg kev noj qab haus huv. Piv txwv, kev siv tshuaj tetracycline mus sij hawm ntev tuaj yeem cuam tshuam kev txhim kho thiab pob txha loj hlob ntawm cov menyuam yaus; tshuaj sulfa tuaj yeem ua rau ua xua tau yooj yim hauv tib neeg.

1. 7 feeb nyeem cov txiaj ntsig

2. Kev txwv tsis pub teb rau EU thiab Asmeskas FDA cov cai

3. Tsis yog cov kws tshaj lij lossis cov cuab yeej xav tau

4. Yooj yim rau kev khiav lag luam thiab nyeem

Trimethoprim Test, raws li txoj kev sib tw kub sib xyaw xim, yog siv rau kev sim Trimethoprim cov seem hauv cov kua mis thiab ua tau raws li EU MRL. Cov khoom siv no tuaj yeem thov rau ntawm qhov chaw sim nrawm los ntawm ntau lub chaw haujlwm.

Cov piv txwv suav nrog: mis nyuj nyoos, mis hmoov, mis nyuj pasteurized.

LOD tuaj yeem hloov pauv raws li qhov xav tau lossis qhov txawv ntawm qhov sib txawv, thov mus saib hauv phau ntawv qhia kom paub meej ntxiv.

Trimethoprim Test tuaj yeem pab cov tuam txhab tsim khoom, cov koom haum tswj hwm, thiab pej xeem saib xyuas cov khoom lag luam zoo thiab pab tib neeg tiv thaiv lawv txoj kev noj qab haus huv.

1. Micro-Well Reagent: 8 kuaj/raj, 12 raj/thawv

2. Xeem Sawb: 8pcs/raj, 96pcs/box

3. Phau Ntawv Qhia: 1pc

1. Qauv Raj

2. Pipette & Pipette Ntsis

3. Zoo-Tais

1. Ntxiv 200ul mis mus rau hauv lub qhov dej, tom qab ntawd xa dej mus thiab nqis rau 10 zaug kom sib xyaw cov qauv nrog cov tshuaj reagent hauv lub qhov dej.

2. Tom qab ntawd muab tso rau 5 feeb.

3. Ntxig daim kab xev ntsuas mus rau hauv lub qhov dej zoo nrog lub qauv ncoo puv dipped.

4. Tom qab 5 feeb, nyeem cov txiaj ntsig.

Thaum tshuaj tua kab mob thawj zaug tau siv rau tib neeg, peb suav tias lawv yog "panacea". Raws li qhov teeb meem ntawm kev siv tshuaj tua kab mob txuas ntxiv mus zuj zus, lawv qhov kev tiv thaiv kuj tseem ua rau muaj kev puas tsuaj loj rau tib neeg.

Yog li, hauv lub neej txhua hnub, peb yuav tsum zam zaub mov nrog tshuaj tua kab mob seem. Thawj kauj ruam rau kev pab tus kheej: peb yuav tsum kuaj cov tshuaj tua kab mob seem.

Thov txheeb xyuas phau ntawv teev npe online thiab tiv tauj peb tus sawv cev muag ntawm email: info@ballyabio.com ib lossis sau daim foos tiv toj hauv qab no: