Tetracyclines Test Rau Qe

Cov Khoom Siv Ib Leeg, nrawm los tshuaj xyuas tetracyclines seem hauv qe thiab qe khoom los ntawm kev siv colloidal kub immuno-chromatography thev naus laus zis. Sai li 7-10 feeb rau cov txiaj ntsig.

Tetracycline yog qhov yooj yim tshaj plaws hauv tsev neeg tetracycline tshuaj tua kab mob. Nws thiab nws cov ntsev yog daj lossis lub teeb daj muaju. Nws ruaj khov heev hauv lub xeev qhuav. Tsuas yog chlortetracycline, cov kua dej ntawm lwm cov tetracycline tsev neeg muaj kev ruaj khov. Tsev neeg tetracycline yog soluble hauv cov kua qaub, dilute alkalis, thiab lwm yam.

Tetracycline tshuaj tua kab mob feem ntau suav nrog chlortetracycline, oxytetracycline, thiab tetracycline. Tetracycline tshuaj tua kab mob muaj cov qauv tshuaj ib txwm muaj. Ob qho tib si chlortetracycline thiab oxytetracycline yog cov txiaj ntsig ntawm tetracycline. Tus qub yog chloretracyelin thiab tom kawg yog oxyeracyein.

Tetracycline thiab Doxycycline yog ib feem ntawm cov tshuaj tua kab mob dav dav hu ua tetracycline tshuaj tua kab mob. Txhua yam tshuaj tua kab mob hauv pawg tshuaj no tau muab los ntawm tib lub plaub-carbon cov qauv yooj yim. Txawm li cas los xij, lub nplhaib tshwj xeeb cov qauv ntawm txhua cov tshuaj sib txawv me ntsis thiab yuav tsum tau pom zoo raws li cov chaw muag tshuaj thiab cov tshuaj tiv thaiv kab mob. Txawm hais tias cov kws kho mob siv ob yam tshuaj no los kho ntau tus kab mob tib yam, lawv tau ua pov thawj tias txhua cov tshuaj feem ntau muaj txiaj ntsig zoo hauv qee yam kev thov.

Qhov sib txawv tseem ceeb ntawm tetracycline thiab doxycycline yog qhov sib txawv hauv pharmacokinetics. Pharmacokinetics hais txog lub cev lus teb rau cov tshuaj tshwj xeeb. Qhov no suav nrog yuav ua li cas lub cev faib tawm thiab metabolizes cov tshuaj, thiab txawm tias tsis suav nrog nws thaum kawg. Piv txwv li, lub cev nqaij daim tawv uas tau hloov pauv los ntawm tetracycline txawv ntawm doxycycline. Cov txheej txheem zom zaub mov ntawm doxycycline nce mus txog qhov siab tshaj plaws hauv lub qhov muag, thaum lub ntsiab lus ntawm tetracycline feem ntau yog hauv lub cev kua.

Tetracycline hydrochloride yog cov tshuaj tua kab mob dav dav, uas muaj qhov cuam tshuam rau feem ntau cov kab mob Gram-positive thiab tsis zoo, muaj cov tshuaj tua kab mob siab ntau, thiab tuaj yeem tiv thaiv Rickettsia, trachomavirus, thiab lwm yam. Nws cov txheej txheem ntawm kev ua yog feem ntau los tiv thaiv kev khi ntawm cov aminoacyl pawg rau ribonucleoprotein lub cev, txhawm rau tiv thaiv kev loj hlob ntawm peptide saw thiab protein synthesis, yog li inhibiting kev loj hlob ntawm cov kab mob. Nws kuj muaj cov kab mob bactericidal ntawm qhov siab.

Tetracycline tshuaj tua kab mob ua rau rov qab sib txuas nrog 30S subunit ntawm cov kab mob sab hauv ribosome txhawm rau tiv thaiv cov protein sib sau thiab ua rau muaj cov tshuaj tua kab mob. Thaum cov tshuaj tua kab mob siab tsawg, qhov kev sib tw thim rov qab sib tw no tseem yuav siv tsis tau, thiab cov kab mob sib txuas ua cov protein ntau yuav txuas ntxiv mus. Tetracycline tseem tuaj yeem tiv thaiv mitochondrial protein synthesis los ntawm kev khi rau mitochondrial 70S subunit. Lub peev xwm khi ntawm tetracycline rau 80S subunit ntawm eukaryotic cells yog qhov tsis muaj zog, yog li lub peev xwm los tiv thaiv cov protein sib sau hauv cov hlwb eukaryotic kuj tseem qaug zog.

Tsawg concentration yog bacteriostatic, thiab siab siab yog kom tsis muaj menyuam. Nws tsis muaj kev cuam tshuam rau kab mob, kab mob thiab Pseudomonas aeruginosa. Cov txiaj ntsig ntawm Gram-positive cov kab mob nyob ze rau ntawm penicillins, thiab cov txiaj ntsig ntawm Gram-negative cov kab mob zoo ib yam li chloramphenicol. Nws yog siv los tiv thaiv thiab kho kab mob ntawm cov kab mob xws li ntses enteritis, tawv nqaij liab thiab cov pos hniav lwj.

Cov tshuaj Canine enteritis. Tetracycline (10-20 mg / kg, ob zaug ib hnub rau 1 txog 2 lub lis piam) tuaj yeem tau txais cov txiaj ntsig zoo. Qee qhov xwm txheej, metronidazole (10-20 mg / kg, ob zaug ib hnub, txuas ntxiv tshuaj rau 1 txog 2 lub lis piam) yog qhov zoo dua vim tias nws tseem muaj cov txiaj ntsig ntawm kev tiv thaiv kab mob anaerobic.

Cov tshuaj Tetracycline tuaj yeem tiv thaiv thiab kho ntau yam kab mob ntawm nqaij qaib, xws li ua npaws kub taub hau, mob plab, mob raws plab, mob synovitis, kis kab mob rhinitis, mob ua pa ntev, kab mob streptococcus, kab mob staphylococcus, listeriosis, kab mob spirochete thiab coccidiosis Tos. Ib qho ntxiv, nws tseem muaj cov txiaj ntsig ntawm kev txo qis kev ntxhov siab, nce qe ntau lawm thiab nce kev tsim qe.

Muaj peb tiam ntawm tshuaj tua kab mob tetracycline.

Thawj cov khoom lag luam chlortetracycline, tetracycline thiab oxytetracycline yog cov tshuaj tua kab mob ntuj, uas tau siv dav vim yog lawv qhov dav, siv tau yooj yim, thiab kev lag luam. Tom qab ntawd, nws tau pom tias cov qauv tshuaj ntawm cov tshuaj tua kab mob no tsis ruaj khov txaus, thiab nws yooj yim los tsim cov tshuaj tiv thaiv kab mob. Kev tiv thaiv kab mob hnyav tau coj mus rau qhov xav tau nrawm los tsim cov tshuaj tua kab mob tetracycline tshiab.

Los ntawm kev hloov kho cov txheej txheem dav dav, lub cim thib ob ib nrab hluavtaws tetracycline tshuaj tua kab mob sawv cev los ntawm doxycycline thiab minocycline. Hom tshuaj tua kab mob no ntau dua li lipophilic thiab muaj txiaj ntsig zoo rau kev khaws cov cell, tab sis nyob rau xyoo tas los no nws cov tshuaj tiv thaiv kab mob tiv taus kab mob tau tshwm sim txuas ntxiv, txwv nws daim ntawv thov tshuaj.

Xyoo 2005, Asmeskas Khoom Noj thiab Tshuaj Yeeb Tshuaj (FDA) tau pom zoo cov npe ntawm tigecycline, uas muaj qhov cuam tshuam tseem ceeb ntawm kev tiv thaiv kab mob Staphylococcus aureus dav thiab tiv thaiv kab mob vancomycin, thiab lub nplhaib glycyl sawv cev los ntawm nws qhov tshwm sim ntawm cov tshuaj tua kab mob cim kev yug ntawm tiam thib peb ntawm tetracycline.


Vim tias qhov tsim nyog tshuaj kho mob thib peb ntawm tetracycline tiv thaiv kab mob tshuaj tiv thaiv kab mob yog kom muaj ntau yam kev hloov pauv ntawm D ntiv nplhaib, xws li glycyl, dimethylamino, thiab fluoro. Nws nyuaj heev los tsim cov qauv no nrog rau cov txheej txheem ib nrab ua hluavtaws dhau los. Nws yog qhov tsim nyog los tsim kho tshiab thiab muaj txiaj ntsig tag nrho cov txheej txheem los tsim D-ring ntau qhov hloov pauv tetracycline pob txha, uas tseem cim qhov kev kawm ntawm tetracycline los ntawm ib nrab ua ke mus rau lub sijhawm tshiab ntawm kev sib xyaw tag nrho.

Thawj yog qhov pom tseeb ntawm lub plab zom mov. Yog tias koj noj cov tshuaj tetracycline qhov ncauj, nws yuav ncaj qha txhawb kev ua haujlwm ntawm lub plab, ua rau muaj cov tsos mob ntawm lub plab xws li xeev siab, ntuav, mob plab, raws plab, tsis xis nyob hauv plab, tsis hnov ​​qab, thiab tsis qab los. Cov tsos mob xws li mob ntawm txoj hlab pas, mob plab, thiab ntshav tuaj yeem tshwm sim.

Qhov thib ob, muaj kev sib kis ob zaug, xws li cov neeg laus tsis muaj zog, vim tias kev siv cov tshuaj glucocorticoids ua ke thiab tshuaj tiv thaiv qog noj ntshav, nws yuav muaj kev kis mob ob zaug.

Thib peb, nws yuav cuam tshuam kev loj hlob ntawm cov pob txha lossis cov hniav, yog li cov menyuam yuav tsum tsis txhob siv nws ntau li ntau tau.

1. 7 feeb nyeem cov txiaj ntsig

2. Kev txwv tsis pub teb rau EU thiab Asmeskas FDA cov cai

3. Tsis yog cov kws tshaj lij lossis cov cuab yeej xav tau

4. Yooj yim rau kev khiav lag luam thiab nyeem

Tetracyclines Test yog colloidal gold immuno-chromatography assay uas tshwj xeeb uas tsim los txhawm rau txheeb xyuas Tetracycline seem hauv qe thiab qe tsim thiab ua tau raws li EU MRL. Cov khoom siv no tuaj yeem thov rau ntawm qhov chaw sim nrawm los ntawm ntau lub chaw haujlwm.

Cov piv txwv muaj xws li: qe thiab khoom qe.

LOD tuaj yeem hloov pauv raws li qhov xav tau lossis qhov txawv ntawm qhov sib txawv, thov mus saib hauv phau ntawv qhia kom paub meej ntxiv.

Kev xeem Tetracyclines tuaj yeem pab cov tuam txhab tsim khoom, cov koom haum tswj hwm, thiab cov pej xeem saib xyuas cov khoom lag luam zoo thiab pab tib neeg tiv thaiv lawv txoj kev noj qab haus huv.

1. Micro-Well Reagent: 8 kuaj/raj, 12 raj/thawv

2. Xeem Sawb: 8pcs/raj, 96pcs/box

3. Phau Ntawv Qhia: 1pc

1. Qauv Raj

2. Pipette & Pipette Ntsis

4. Zoo-Phaj

1. Ntxiv 200ul kev sim tshuaj rau hauv lub qhov dej, tom qab ntawd pipet nce thiab nqis rau 10 zaug kom sib xyaw cov qauv nrog cov tshuaj reagent hauv lub qhov dej.

2. Tom qab ntawd muab tso rau 3 feeb.

3. Ntxig qhov ntsuas ntsuas mus rau hauv lub qhov dej zoo nrog cov qauv ntsuas phoo tag nrho.

4. Tom qab 5 feeb, nyeem cov txiaj ntsig.

Thaum tshuaj tua kab mob tau siv thawj zaug rau tib neeg, peb suav tias lawv yog "tshuaj khawv koob". Raws li qhov teeb meem ntawm kev siv tshuaj tua kab mob txuas ntxiv mus zuj zus, lawv qhov kev tiv thaiv kuj tseem ua rau muaj kev puas tsuaj loj rau tib neeg.

Yog li, hauv lub neej txhua hnub, peb yuav tsum zam zaub mov nrog tshuaj tua kab mob seem. Thawj kauj ruam rau kev pab tus kheej: peb yuav tsum kuaj cov tshuaj tua kab mob seem.

Thov txheeb xyuas phau ntawv teev npe online thiab tiv tauj peb tus sawv cev muag ntawm email: info@ballyabio.com ib lossis sau daim foos tiv toj hauv qab no: