Quinolones Test Rau Qe

Cov Khoom Siv Ib Leeg, nrawm los txheeb xyuas Quinolones seem hauv cov qe thiab cov khoom lag luam los ntawm kev siv colloidal kub tiv thaiv-chromatography thev naus laus zis. Sai li 7-10 feeb rau cov txiaj ntsig.

Quinolones (4-quinolones), tseem hu ua pyruvates lossis pyridone acids, yog chav kawm ntawm cov tshuaj siv tshuaj tua kab mob sib kis. Quinolones yog cov tshuaj tua kab mob uas feem ntau ua rau cov kab mob Gram-tsis zoo thiab muaj qhov ua tsis tau zoo ntawm cov kab mob Gram-positive (qee yam muaj cov tshuaj tua kab mob zoo dua ntawm Staphylococcus aureus).

Cov tub ntxhais 4-quinolone muaj cov carboxylic acid pawg ntawm 3 txoj haujlwm, qhia txog cov tshuaj fluorine atom ntawm 6 txoj haujlwm tuaj yeem txhim kho cov tshuaj tua kab mob thiab ua haujlwm tiv thaiv kab mob ntawm Staphylococcus aureus; kev qhia txog cov yeeb nkab piperazine ntawm 7 txoj haujlwm tuaj yeem txhim kho cov tshuaj tua kab mob tiv thaiv Staphylococcus aureus thiab Pseudomonas aeruginosa Role (xws li norfloxacin), lub nplhaib piperazine tau hloov los ntawm lub nplhaib methylpiperazine (xws li pefloxacin), tom qab ntawd cov rog rog nce ntxiv, kev nqus ntawm plab hnyuv nce, kev nkag mus ntawm tes nce, thiab ib nrab ntawm lub neej tau txuas ntxiv. 

Kev qhia txog cov tshuaj fluorine thib ob ntawm 8 txoj haujlwm tuaj yeem txhim kho kev nqus dej hauv plab thiab txuas ntxiv ib nrab ntawm lub neej (xws li lomefloxacin, thiab lwm yam), N-1 hloov kho nrog pab pawg cyclopropyl (ciprofloxacin) lossis pab pawg oxazine (oxyfluoride (Floxacin) tuaj yeem nthuav dav cov kab mob tua kab mob thiab txhim kho kev tiv thaiv kab mob tiv thaiv kab mob chlamydia, mycoplasma thiab mycobacteria (tuberculosis thiab mob ruas, thiab lwm yam). Lub nplhaib oxazine kuj tseem tuaj yeem ua kom dej nkag tau yooj yim dua, yog li cov tshuaj tsis tau metabolized hauv lub cev thiab tso tawm los ntawm cov zis hauv daim ntawv qub.

Cov pob txha yooj yim ntawm cov tshuaj tua kab mob quinolone yog txhua yam nitrogen (hetero) cov qauv tsheb kauj vab. Quinolone thiab lwm yam tshuaj tua kab mob muaj cov ntsiab lus sib txawv. Lawv tsom cov kab mob deoxyribonucleic acid (DNA). Qhov ob-kab DNA ntawm cov kab mob tau muab ntxig rau hauv cov kab lossis kab sib chaws (hu ua supercoils). 

Cov enzyme uas ua rau DNA tsim supercoils hu ua DNA gyrase, thiab quinolones cuam tshuam cov enzyme no, txuas ntxiv ua rau tsis tuaj yeem ua puas rau cov kab mob DNA thiab ua rau cov kab mob, cov cell tsis faib ntxiv lawm. Lawv qhia pom cov tshuaj lom rau cov kab mob. Tam sim no, qhov tsis kam ntawm qee cov kab mob rau ntau yam tshuaj tua kab mob tuaj yeem nthuav dav vim yog kis plasmid.

Quinolone tau muab faib ua thawj, thib ob, thib peb, thiab plaub tiam raws li qhov kev txiav txim ntawm kev tsim khoom thiab nws cov tshuaj tua kab mob.

Thawj-tiam quinolones tsuas muaj cov tshuaj tua kab mob rau Escherichia coli, Shigella, Klebsiella, thiab ob peb Proteus. Vim tias qhov ua tsis tau zoo, nws tsis tshua tau siv.

Lub cim thib ob quinolones tau nthuav lawv cov kab mob tua kab mob, thiab muaj qee yam tshuaj tua kab mob tiv thaiv Enterobacter, Citrobacter, Pseudomonas aeruginosathiab Serratia.

Cov kab mob tua kab mob ntawm cov cim thib peb quinolones tau nthuav dav ntxiv. Nws kuj muaj cov tshuaj tua kab mob rau cov kab mob gram-positive xws li staphylococcus, thiab ntxiv dag zog rau cov kab mob tiv thaiv kab mob rau qee cov kab mob gram-negative. Cov tshuaj tiam no muaj cov tshuaj fluorine nyob hauv cov molecules. Yog li ntawd, hu ua fluoroquinolone.

Plaub tiam quinolones tau hloov kho tus qauv piv rau cov tshuaj peb tiam dhau los. Kev qhia txog 8-methoxy pawg hauv cov qauv pab txhawb kev ua haujlwm tiv thaiv kab mob anaerobic, thaum cov qauv azadioxane ntawm C-7 txoj haujlwm ntxiv dag zog rau kev tiv thaiv kab mob gram zoo thiab ua thawj qhov haujlwm tiv thaiv kab mob Gram-negative, tsis zoo. cov tshuaj tiv thaiv me dua, tab sis tus nqi kim dua. Ua kom muaj zog tiv thaiv kab mob tiv thaiv kab mob Gram-positive, ua rau muaj kev cuam tshuam ntau ntxiv ntawm cov kab mob anaerobic suav nrog Bacteroides fragilis, thiab txhim kho cov txiaj ntsig ntawm cov kab mob zoo xws li Mycoplasma mob ntsws, Chlamydia mob ntsws dej, Legionella thiab Mycobacterium tuberculosis.

Cov tshuaj Quinolone muaj cov ntsiab lus hauv qab no: nalidixic acid, pipemidic acid, norfloxacin, ciprofloxacin, enoxacin, ofloxacin, levofloxacin, fleroxacin, lomefloxacin, pefloxacin, txo Ofloxacin, Sifloxacin, thiab lwm yam.

Cov tshuaj Quinolone tau siv dav hauv kev kho tib neeg thiab tsiaj txhu kab mob. Vim tias qhov seem ntawm cov tshuaj quinolone hauv cov nqaij hauv lub cev, cov tshuaj tua kab mob quinolone tau sau rau hauv tib neeg lub cev tom qab tib neeg noj cov nqaij nqaij, ua rau muaj kev mob siab rau tib neeg kab mob rau cov tshuaj Cov tshuaj muaj txiaj ntsig cuam tshuam rau kev kho tib neeg kab mob. 

Raws li cov lus hais mus, nws yog cov tshuaj uas ua rau peb txoj kev lom. Kev noj cov zaub mov tau ntev uas muaj cov quinolones muaj kev phom sij rau tib neeg lub cev tab sis tsis muaj txiaj ntsig.

A. Cov kab mob hauv plab: xeev siab, ntuav, tsis xis nyob, mob, thiab lwm yam;

B. Qhov tshwm sim hauv nruab nrab: mob taub hau, kiv taub hau, pw tsis tsaug zog, thiab lwm yam, thiab tuaj yeem ua rau muaj kev puas siab puas ntsws;

C. Vim tias chav kawm ntawm cov tshuaj no tuaj yeem cuam tshuam γ-aminobutyric acid (GABA), nws tuaj yeem ua rau qaug dab peg, thiab cov uas muaj keeb kwm mob vwm yuav tsum tau siv nrog ceev faj;

D. Hom tshuaj no tuaj yeem cuam tshuam kev txhim kho pob txha mos, poj niam cev xeeb tub thiab menyuam yaus yuav tsum tau ceev faj.

E. Crystalline zis tuaj yeem tsim tawm, tshwj xeeb tshaj yog cov zis alkaline;

F. Kev siv tshuaj loj lossis siv sijhawm ntev ntawm cov tshuaj no yuav ua rau lub siab puas.

A. Cov tshuaj Alkaline, tshuaj anticholinergic, thiab H2 receptor blockers tuaj yeem txo qis cov kua qaub hauv plab thiab txo qhov nqus ntawm cov tshuaj no.

B. Rifampicin (inhibitor ntawm RNA synthesis) thiab chloramphenicol (inhibitor protein synthesis) tuaj yeem txo cov teebmeem ntawm cov tshuaj no, tshem tawm cov teebmeem ntawm nalidixic acid thiab haloperic acid, thiab ua rau fluazamic acid Cov nyhuv ntawm ciprofloxacin yog ib nrab offset.

C. Fluoroquinolones tuaj yeem cuam tshuam cov metabolism hauv theophylline. Thaum ua ke nrog theophylline, cov ntshav plasma ntawm theophylline yuav nce ntxiv, thiab cov tshuaj lom tshuaj lom ntawm theophylline yuav tshwm sim, yog li yuav tsum tau them nyiaj mloog.

Ua pob, khaus ntawm daim tawv nqaij, thiab qee zaum exudative erythema multiforme thiab angioedema. Tsawg tus neeg mob nrog cov kab mob photosensitive muaj cov tshuaj tiv thaiv photosensitive.

1.7 feeb nyeem cov txiaj ntsig

2. Kev txwv tsis pub teb rau EU thiab Asmeskas FDA cov cai

3. Tsis yog cov kws tshaj lij lossis cov cuab yeej xav tau

4. Yooj yim rau kev khiav lag luam thiab nyeem

Quinolones Test Kit yog colloidal kub tiv thaiv-chromatography kuaj uas tshwj xeeb uas tsim los txhawm rau tshuaj xyuas sulfonamides seem hauv cov qe thiab cov khoom qe thiab ua tau raws li EU MRL. Cov khoom siv no tuaj yeem thov rau ntawm qhov chaw sim nrawm los ntawm ntau lub chaw haujlwm.

Cov piv txwv muaj xws li: qe thiab khoom qe

LOD tuaj yeem hloov pauv raws li qhov xav tau lossis qhov txawv ntawm qhov sib txawv, thov mus saib hauv phau ntawv qhia kom paub meej ntxiv.

Kev ntsuas Quinolones tuaj yeem pab cov tuam txhab tsim khoom, cov koom haum tswj hwm, thiab pej xeem saib xyuas cov khoom lag luam zoo thiab pab tib neeg tiv thaiv lawv txoj kev noj qab haus huv.

1. Micro-Well Reagent: 8 kuaj/raj, 12 raj/thawv

2. Xeem Sawb: 8pcs/raj, 96pcs/box

3. Phau Ntawv Qhia: 1pc

1. Qauv Raj

2. Pipette & Pipette Tip

3. Zoo-Tais

1. Ntxiv 200ul kev sim tshuaj rau hauv lub qhov dej, tom qab ntawd pipet nce thiab nqis rau 10 zaug kom sib xyaw cov qauv nrog cov tshuaj reagent hauv lub qhov dej.

2. Tom qab ntawd muab tso rau 3 feeb.

3. Ntxig daim ntawv xeem rau hauv micro-zoo-phaj nrog cov qauv ncoo siab dipped.

4. Tom qab 5 feeb, nyeem cov txiaj ntsig.

Thaum tshuaj tua kab mob tau siv thawj zaug rau tib neeg, peb suav tias lawv yog "nostrum". Raws li qhov teeb meem ntawm kev siv tshuaj tua kab mob txuas ntxiv mus zuj zus, lawv qhov kev tiv thaiv kuj tseem ua rau muaj kev puas tsuaj loj rau tib neeg.

Yog li, hauv lub neej txhua hnub, peb yuav tsum zam zaub mov nrog tshuaj tua kab mob seem. Thawj kauj ruam rau kev pab tus kheej: peb yuav tsum kuaj cov tshuaj tua kab mob seem.

Thov txheeb xyuas phau ntawv teev npe online thiab tiv tauj peb tus sawv cev muag ntawm email: info@ballyabio.com ib lossis sau daim foos tiv toj hauv qab no: