Chloramphenicol Test

Cov Khoom Siv Ib Leeg, nrawm txhawm rau txheeb xyuas Chloramphenicol seem hauv cov mis thiab khoom siv mis los ntawm kev siv colloidal kub immunochromatography thev naus laus zis. Sai li 7-10 feeb rau cov txiaj ntsig.

Chloramphenicol tshuaj tua kab mob suav nrog chloramphenicol, Thiamphenicol thiab tsis muaj ntxhiab chloramphenicol. Nws yog cov tshuaj tua kab mob sib kis dav sib cais los ntawm Streptomyces venezuela. 

Nws muaj qhov cuam tshuam rau ntau yam kab mob aerobic gram-positive thiab kab mob gram-negative, anaerobic Bacteroides, Rickettsia, Chlamydia thiab mycoplasma, tshwj xeeb tshaj yog rau Salmonella, Influenza bacillus thiab Bacteroides, thiab lwm yam.

Chloramphenicol tau ua tiav kev cais tawm thawj zaug hauv xyoo 1947, thiab nws tau sib xyaw ua ke tshuaj hauv lub xyoo tom ntej. Nws tau siv los ua tshuaj tua kab mob muaj txiaj ntsig zoo rau kev kho mob khaub thuas, kab mob rickettsial thiab lwm yam kab mob sib kis, tab sis ob peb tus neeg mob tsim cov ntshav tsis txaus tom qab siv tshuaj chloramphenicol. 

Qhov no yog qhov teeb meem loj ntawm tus neeg mob lub pob txha pob txha hematopoietic tsis ua haujlwm los ntawm cov tshuaj, yog li nws qhov kev thov dav dav raug txwv.

70S ribosome ntawm cov kab mob hauv lub cev yog lub hauv paus tseem ceeb ntawm cov cell rau kev sib txuas ntawm cov protein, thiab nws suav nrog ob lub subunits, 50S thiab 30S. 

Chloramphenicol thim rov qab khi rau 50S subunit txhawm rau thaiv qhov kev ua ntawm transpeptidylase, cuam tshuam nrog cov amino acid-tRNA davhlau ya nyob twg nrog cov amino acids thiab 50S subunit binding, yog li cuam tshuam kev tsim peptide saw tshiab thiab txwv tsis pub muaj protein ntau synthesis. 

Txij li thaum chloramphenicol tseem tuaj yeem khi rau 70S ntawm tib neeg mitochondria, nws tseem tuaj yeem cuam tshuam cov protein synthesis ntawm tib neeg mitochondria, ua rau muaj tshuaj lom rau tib neeg lub cev. 

Vim tias kev khi ntawm chloramphenicol rau 70S ribosomes tuaj yeem thim rov qab, nws tau txiav txim siab tias yog cov tshuaj tua kab mob bacteriostatic, tab sis nws kuj tseem tuaj yeem muaj cov kab mob tua kab mob rau qee cov kab mob ntawm cov tshuaj ntau ntau, thiab nws tuaj yeem siv tau zoo tiv thaiv kab mob khaub thuas bacilli ntawm qhov qis.

Nws muaj qhov dav-spectrum antimicrobial effect hauv vitro, suav nrog aerobic gram-negative bacteria thiab gram-positive bacteria, anaerobic bacteria, rickettsia, spirochetes thiab chlamydia. Nws muaj cov kab mob tua cov kab mob hauv qab no: Haemophilus influenzae, Streptococcus pneumoniae thiab Neisseria meningitidis.

Nws tsuas muaj cov tshuaj tua kab mob rau cov kab mob hauv qab no: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Pawg B hemolytic streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella tus kab mob, paratyphoid Anaerobic cov kab mob xws li Salmonella, Shigella, Bacteroides fragilis. 

Cov kab mob hauv qab no feem ntau tiv taus chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, Indole-positive Proteus, methicillin-resistant Staphylococcus, thiab Enterococcus. Cov khoom no yog tus neeg sawv cev bacteriostatic.

Chloramphenicol yog cov roj-soluble, nthuav tawm rau hauv cov kab mob hauv cov kab mob, thiab thim rov qab khi rau 50S subunit ntawm cov kab mob ribosome, thaiv qhov kev loj hlob ntawm peptide saw (tejzaum nws vim yog qhov cuam tshuam ntawm cov nyhuv ntawm transpeptidase), yog li inhibiting tsim ntawm peptide saw, yog li tiv thaiv cov protein synthesis.

Chloramphenicol siv los kho ntau yam kab mob sib kis hauv dev thiab miv, suav nrog kab mob ntawm daim tawv nqaij, kis kab mob, mob pob txha, mob hauv nruab nrab lub paj hlwb (kab mob hauv siab, mob meningitis), mob ntsws, thiab mob plab (xws li raws plab). 

Chloramphenicol tau siv los kho kab mob ib leeg-cell kab mob hauv tsiaj thiab kab mob kis los ntawm tus kab mob xws li Rocky Mountain pom kub taub hau. Chloramphenicol tsis muaj txiaj ntsig zoo tiv thaiv kev kis mob los ntawm cab (kab mob hauv plab), kab, kab mob lossis kab mob hu ua fungi.

Chloramphenicol yog tshuaj tua kab mob dav thiab tau siv dav hauv kev tu tsiaj txhu. Txawm li cas los xij, chloramphenicol muaj cov kev mob tshwm sim muaj zog thiab muaj tshuaj lom. 

Yog tias chloramphenicol tseem nyob hauv tsiaj cov khoom noj, nws tuaj yeem kis mus rau tib neeg los ntawm cov khoom noj khoom haus, thiab cov kab ke mus sij hawm ntev tsis yog tsuas yog ua rau tib neeg lub cev zom zaub mov tsis zoo, tab sis kuj ua rau muaj ntau yam kab mob thiab tsim kev puas tsuaj. 

Ntau lub tebchaws hauv ntiaj teb txwv tsis pub siv cov tshuaj no hauv kev tsim tsiaj cov zaub mov thiab sau tseg tias Chloramphenicol siv hauv cov khoom tsiaj tsis tuaj yeem kuaj pom. 

Muaj ntau txoj hauv kev kuaj pom chloramphenicol qhov seem, thiab cov txheej txheem tshawb pom sib txawv muaj qhov txwv tsis pub nrhiav pom sib txawv. Qhov ntsuas pom tau dhau los ua qhov tseem ceeb ntawm kev saib xyuas, thiab kev tshawb pom txwv ntawm cov tebchaws tau tsim kho yog nruj dua.

Qee cov ntaub ntawv qhia tias yog tias kev noj zaub mov ntev uas muaj cov tshuaj chloramphenicol nyob hauv qhov me me tsis tuaj yeem tsuas yog ua rau E. coli, Salmonella thiab lwm yam kab mob uas tiv taus cov kab mob, tab sis kuj ua rau lub cev tsis zoo li qub, yog li ua rau muaj kab mob ntau yam. 

Qhov phom sij tshaj plaws yog qhov cuam tshuam ntawm cov leeg pob txha ua haujlwm hematopoietic. Feem ntau nws ua rau txo qis ntawm ntau hom qe ntshav. Cov tshuaj tiv thaiv no cuam tshuam nrog koob tshuaj thiab chav kawm ntawm kev kho. Thaum pom cov tsos mob no, cov tshuaj yuav tsum raug tso tseg hauv lub sijhawm.

Cov menyuam mos thiab menyuam yaus muaj kev txhim kho lub siab tsis zoo, tso zis tsis zoo, thiab txwv tsis pub cov metabolism hauv chloramphenicol thiab cov txheej txheem tshem tawm, uas ua rau muaj cov tshuaj ntau ntxiv hauv lub cev thiab tsis ua haujlwm, feem ntau hu ua "grey tus menyuam syndrome". 

European Union, Tebchaws Asmeskas thiab lwm lub tebchaws tau teev tseg tias qhov txwv tsis pub muaj chloramphenicol hauv cov khoom noj los ntawm tsiaj yog "xoom tsis kam", uas yog, tsis muaj kev kuaj pom. Hauv qhov xwm txheej no, Tuam Tshoj tseem tau tsim ntau yam kev ntsuas los txwv kev siv chloramphenicol. 

Txawm li cas los xij, vim nws tus nqi qis thiab muaj txiaj ntsig zoo rau kev kho, qhov tshwm sim ntawm kev siv tshuaj kho mob chloramphenicol tseem muaj nyob, ua rau pom muaj ntau zaus ntawm chloramphenicol hauv Suav teb cov khoom lag luam tsiaj txhu, uas tau cuam tshuam loj heev rau Tuam Tshoj txoj kev lag luam txawv teb chaws muag thiab cov duab thoob ntiaj teb.

1. 7 feeb nyeem cov txiaj ntsig

2. Kev txwv tsis pub teb rau EU thiab Asmeskas FDA cov cai

3. Tsis yog cov kws tshaj lij lossis cov cuab yeej xav tau

4. Yooj yim rau kev khiav lag luam thiab nyeem

Chloramphenicol Test, raws li txoj kev sib tw kub sib xyaw xim, yog siv rau kev sim Chloramphenicol cov seem hauv cov kua mis thiab ua tau raws li EU MRL. Cov khoom siv no tuaj yeem thov rau ntawm qhov chaw sim nrawm los ntawm ntau lub chaw haujlwm.

Cov piv txwv suav nrog: mis nyuj nyoos, mis hmoov, mis nyuj pasteurized.

LOD tuaj yeem hloov pauv raws li qhov xav tau lossis qhov txawv ntawm qhov sib txawv, thov mus saib hauv phau ntawv qhia kom paub meej ntxiv.

Chloramphenicol Test tuaj yeem pab cov tuam txhab tsim khoom, cov koom haum tswj hwm, thiab pej xeem saib xyuas cov khoom lag luam zoo thiab pab tib neeg tiv thaiv lawv txoj kev noj qab haus huv.

1. Micro-Well Reagent: 8 kuaj/raj, 12 raj/thawv

2. Xeem Sawb: 8pcs/raj, 96pcs/box

3. Phau Ntawv Qhia: 1pc

1. Qauv Raj

2. Pipette & Pipette Ntsis

3. Zoo-Tais

1. Ntxiv 200ul mis mus rau hauv lub qhov dej, tom qab ntawd xa dej mus thiab nqis rau 10 zaug kom sib xyaw cov qauv nrog cov tshuaj reagent hauv lub qhov dej.

2. Tom qab ntawd muab tso rau 3 feeb.

3. Ntxig daim ntawv xeem rau hauv micro-zoo-phaj nrog cov qauv ncoo siab dipped.

4. Tom qab 5 feeb, nyeem cov txiaj ntsig.

Thaum tshuaj tua kab mob tau siv thawj zaug rau tib neeg, peb suav tias lawv yog "tshuaj khawv koob". Raws li qhov teeb meem ntawm kev siv tshuaj tua kab mob txuas ntxiv mus zuj zus, lawv qhov kev tiv thaiv kuj tseem ua rau muaj kev puas tsuaj loj rau tib neeg.

Yog li, hauv lub neej txhua hnub, peb yuav tsum zam zaub mov nrog tshuaj tua kab mob seem. Thawj kauj ruam rau kev pab tus kheej: peb yuav tsum kuaj cov tshuaj tua kab mob seem.

Thov txheeb xyuas daim ntawv teev npe online thiab tiv tauj peb tus sawv cev muag khoom ntawm email: info@ballyabio.com lossis ua daim ntawv tiv toj hauv qab no: