BALLYA Sulfanilamide Test yog dab tsi?
BALLYA Sulfanilamide Test yog tsim los ntawm BALLYA, nws tau sim sai rau kev kuaj xyuas sulfanilamide seem hauv nqaij qaib, nqaij qaib, menyuam yaj, nqaij npuas lossis nqaij muv, tshwj xeeb yog nqaij npuas. Lateral flow assay kuaj lub hauv paus ntawm cov tshuaj tiv thaiv kab mob kub immunochromatography.
Tau Txais Tus Nqi Pub Dawb!Sulfanilamide yog dab tsi?
Sulfonamide, mis mos molecular: C6H8N2O2S, dawb granule lossis hmoov siv lead ua, tsis muaj ntxhiab, me ntsis iab saj Me ntsis soluble hauv dej txias, ethanol, methanol, ether thiab acetone, yooj yim soluble hauv dej kub, glycerin, hydrochloric acid, potassium hydroxide thiab sodium hydroxide daws, insoluble hauv chloroform, ether, benzene, roj av ether. Nws tuaj yeem npaj los ntawm acetanilide los ntawm chlorosulfonation, amination, hydrolysis, thiab nruab nrab.
Solubility ntawm sulfanilamide
Solubility: Me ntsis soluble hauv dej txias, ethanol, methanol, ether thiab acetone, yooj yim soluble hauv dej kub, glycerin, hydrochloric acid, potassium hydroxide thiab sodium hydroxide daws, insoluble hauv chloroform, ether, benzene, roj av ether.
Sulfanilamide synthesis
Nws yog tsim los ntawm acetanilide los ntawm chlorosulfonation, amination, hydrolysis thiab neutralization. Kev siv cov khoom nyoos quota: acetanilide (99%) 1032 kg / t, chlorosulfonic acid (96%) 4521 kg / t, kua ammonia (99.8%) 535 kg / t, kua alkali (30%) 863 kg / t.
Sulfonamides mechanism ntawm kev ua
Cov kab mob tsis tuaj yeem siv folic acid ncaj qha hauv lawv qhov chaw loj hlob, tab sis siv p-aminobenzoic acid (PABA), dihydropyridinium thiab glutamic acid hauv ib puag ncig los ua ke dihydrofolate nyob rau hauv catalysis ntawm dihydrofolate synthetase hauv cov kab mob. Dihydrofolate daim ntawv tetrahydrofolate nyob rau hauv qhov kev txiav txim ntawm dihydrofolate reductase. Tetrahydrofolate ua raws li coenzyme rau ib-carbon chav transferase thiab koom nrog hauv kev sib xyaw ntawm cov nucleic acid ua ntej (purine, pyrimidine). Cov nucleic acid yog cov khoom tsim nyog rau kev loj hlob ntawm cov kab mob thiab rov tsim dua tshiab. Cov qauv tshuaj lom neeg ntawm tshuaj sulfa zoo ib yam li PABA. Nws tuaj yeem sib tw nrog PABA rau dihydrofolate synthase, uas cuam tshuam rau kev sib xyaw ntawm dihydrofolate thiab yog li ua rau cuam tshuam kev loj hlob thiab tsim cov kab mob.
Sulfanilamide siv li cas?
Cov tshuaj sulfonamides
Cov tshuaj sulfonamides yog cov tshuaj tua kab mob tua kab mob uas tau siv hauv tsev kho mob tau ze li 50 xyoo. Lawv muaj qhov zoo ntawm cov tshuaj tua kab mob dav dav, ruaj khov, siv tau yooj yim, thiab tsis muaj zaub mov noj thaum tsim khoom.
Sulfonamides npe
Raws li kev siv tshuaj kho mob, nws tuaj yeem faib ua peb pawg:
1. Cov tshuaj sulfa hauv plab tau nqus tau yooj yim. Feem ntau yog siv rau kev kis kab mob;
2. Cov hnyuv sulfonamides nyuaj rau nqus. Feem ntau siv rau kev mob plab hnyuv;
3. Tshuaj pleev sulfa. Feem ntau yog siv rau kev kis mob, mob txhab rau qhov txhab, kab mob ntawm lub qhov muag, thiab lwm yam.
Sulfanilamide phiv li cas?
1. Cov tshuaj tiv thaiv kab mob ntshav
Hemolytic anemia yuav tshwm sim, uas yog tshwm sim tom qab siv sulfonamides hauv cov neeg mob uas tsis muaj piam thaj-6-phosphate dehydrogenase; granulocytopenia thiab thrombocytopenia kuj tuaj yeem pom.
2. Lub siab puas
Jaundice, ua rau daim siab tsis ua haujlwm, thiab mob siab necrosis tuaj yeem tshwm sim thaum mob hnyav.
3. Cov kab mob hauv lub cev puas
Ntau qhov siv lead ua zis, mob, hematuria thiab lwm yam. Nws tuaj yeem tiv thaiv cov zis PH thiab haus dej ntau dua.
4. Lwm yam
Qee zaum jaundice nuclear, siv zis zis, thiab lwm yam.
Sulfonamide phiv tshuaj
1. Ua xua. Feem ntau yog tawv nqaij thiab ua npaws. Feem ntau nws tshwm sim 5-9 hnub tom qab siv tshuaj, thiab nws tshwm sim ntau dua rau menyuam yaus.
2. Lub raum puas. Vim tias qhov txo qis ntawm acesulfame, tshwj xeeb tshaj yog thaum cov zis muaj cov kua qaub, cov nplais tau yooj yim los nag hauv lub raum tubules, ua rau muaj cov tsos mob xws li hematuria, dysuria thiab tso zis.
3. Qhov cuam tshuam ntawm cov txheej txheem hematopoietic. Cov tshuaj Sulfonamide tuaj yeem tiv thaiv kev tsim cov pob txha pob txha mos ua rau cov ntshav dawb, ua rau muaj kab mob leukopenia.
4. Lub hauv nruab nrab lub paj hlwb thiab lub plab zom mov. Feem ntau vim muaj cov tshuaj sulfa txaus.
Kev tsis haum tshuaj sulfonamide
Kev ua xua rau tshuaj sulfa yog ib txwm muaj. Cov tshuaj tiv thaiv tsis zoo ntawm sulfa tshuaj tua kab mob yog kwv yees li 3%, uas ze rau penicillin.
Feem ntau yog tawv nqaij thiab ua npaws. Feem ntau nws tshwm sim 5-9 hnub tom qab siv tshuaj, thiab nws tshwm sim ntau dua rau menyuam yaus. Muaj kev ua xua sib txawv ntawm cov tshuaj sulfa, yog li thaum tus neeg mob ua xua rau ib yam tshuaj sulfa, nws tsis nyab xeeb hloov mus rau lwm cov tshuaj sulfa. Thaum muaj kev tsis haum tshuaj tshwm sim, cov tshuaj yuav tsum nres tam sim ntawd. Cov tshuaj sulfa uas ua haujlwm ntev yog qhov txaus ntshai heev vim tias lawv muaj kev sib khi siab rau cov ntshav protein, thiab muaj cov tshuaj hauv cov ntshav ob peb hnub tom qab siv tshuaj.
Sulfa tshuaj ua xua syndrome
Sulfonamide hypersensitivity syndrome zoo ib yam li anticonvulsant hypersensitivity syndrome, tab sis feem ntau nws tshwm sim ua ntej thaum kho (feem ntau 7-14 hnub tom qab kho).
Dab tsi yog Sulfanilamide elixir
Diethylene glycol tau siv tsis yog cawv ua cov kuab tshuaj los npaj cov kua hauv qhov ncauj nrog xim, ntxhiab thiab saj, hu ua Sulfanilamide elixir.
Kev tu siab Sulfanilamide elixir
Xyoo 1937, HaroldWotkins, tus thawj kws muag tshuaj ntawm tuam txhab Asmeskas, siv diethylene glycol tsis yog cawv ua cov kuab tshuaj kom yooj yim rau menyuam yaus, thiab npaj cov kua ua kua hauv qhov ncauj nrog rau xim, ntxhiab tsw, thiab saj, hu ua sulfonamide elixir. Kev sim tsiaj, tom qab tau muab tso rau hauv ntau lawm ntawm Masson Gill Pharmaceuticals hauv Tennessee, txhua tus tau nkag mus rau hauv kev ua lag luam rau kev kho mob sib kis. Lub sijhawm ntawd, Asmeskas txoj cai tso cai tshuaj tshiab nkag mus rau tom khw yam tsis muaj kev sim tshuaj. Txij lub Cuaj Hli mus txog Lub Kaum Hli xyoo no, qee qhov chaw nyob rau yav qab teb Asmeskas tau pib pom cov neeg mob raum tsis ua haujlwm ntau ntxiv, thiab pom tag nrho 358 tus neeg mob, thiab 107 tuag (feem ntau yog menyuam yaus), dhau los ua tus muaj feem cuam tshuam tshuaj ntawm lub xyoo pua xeem Ib qhov teeb meem tshwm sim. Xyoo 1937, "xwm txheej sulfonamide elixir" ua rau US Congress kom dhau Txoj Cai Khoom Noj, Tshuaj, thiab Tshuaj Zoo Nkauj (Khoom Noj, Tshuaj, thiab Tshuaj Kho Kom Zoo, FDCA, 1938), uas muaj kev cuam tshuam loj rau Western lub tsev muag tshuaj.
Dab tsi tuaj yeem kuaj pom los ntawm BALLYA Sulfanilamide Test?
Cov piv txwv suav nrog: nqaij qaib, nqaij qaib, menyuam yaj, nqaij npuas lossis khoom qab zib, thiab lwm yam Siv dav hauv nqaij qaib thiab nqaij npuas lag luam.
Qhov tseem ceeb ntawm kev sim Sulfanilamide
Txhawm rau tiv thaiv tib neeg kom muaj zaub mov noj qab haus huv thiab zam cov zaub mov tsis huv. Sulfanilamide yog teeb meem rau tib neeg, tsis tuaj yeem siv ntau hauv lub cev.
Cheebtsam ntawm BALLYA Sulfanilamide Test?
BALLYA Sulfanilamide Test, 25 kab xev
Qauv Tsis, 1 vial
Mini Pipette (Optional)
Cov lus qhia micropipette pov tseg (xaiv tau)
Cov Khoom Qhia, 1pcs
Yuav siv BALLYA Sulfanilamide Test li cas?
1. Nqa nqaij qaib, nqaij qaib, menyuam yaj, nqaij npuas lossis nqaij npua piv txwv
2. Ntxiv cov supernatant rau daim kab xev
3. Tos li 15 feeb kom tiav
4. Cov ntsiab lus ntawm kev ua haujlwm, xa mus rau cov lus qhia hauv pob khoom
Cov kev txwv ntawm BALLYA Sulfanilamide Test?
BALLYA Sulfanilamide Test yog ib qho khoom siv xeem zoo. Nws tsuas yog siv los tshuaj xyuas lub hom phiaj. Yog tias muaj cov xwm txheej zoo lossis xav tias kis mob, tej zaum siv lwm txoj hauv kev txhawm rau txhawm rau tshawb nrhiav ntxiv, xws li, ELISA, PCR, qPCR, thiab lwm yam.
xaus
Raws li tshuaj kho tsiaj, cov khoom no tau nqus sai sai tab sis tsis tag. Nws tau faib dav hauv tsiaj thiab tuaj yeem nkag mus rau cov ntaub so ntswg thiab lub cev ua kua zoo. Feem ntau tawm ntawm cov zis hauv daim ntawv ntawm cov tshuaj qub. Tab sis nws yog qhov tsis yooj yim sua uas yuav muaj tshuaj nyob hauv lub cev. Qhov no yuav ua rau Sulfanilamide seem hauv nqaij qaib, nyuj thiab yaj. Nws yog qhov tsim nyog los tshuaj xyuas Sulfanilamide hauv nqaij qaib, nqaij npuas thiab menyuam yaj.
BALLYA Sulfanilamide Test yog muab los ntawm
BALLYA tuaj yeem tshawb pom tau zoo thiab sai sai seb nqaij qaib, nqaij npuas thiab yaj muaj Sulfanilamide seem. Tsis yog tsuas yog kev ua haujlwm yooj yim thiab lub sijhawm nrhiav pom tau luv.
Qhov twg yuav BALLYA Sulfanilamide Test?
Tau txais daim ntawv pub dawb tam sim no thiab txaus siab rau 10% luv nqi!
