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Florfenicol Test For Chicken(R&D)

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beta-lactams-Test-Kit

For various types of chicken

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Florfenicol Test For Chicken

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Do you know florfenicol?

About florfenicol

Florfenicol is a monofluorinated derivative of thiamphenicol, which is white or off-white crystalline powder, odorless. Very slightly soluble in water and chloroform, slightly soluble in glacial acetic acid, soluble in methanol and ethanol. It is a new broad-spectrum antibacterial drug for veterinary medicine developed successfully in the late 1980s.

Florfenicol mechanism of action

This product can disperse into bacterial cells through fat solubility, mainly acting on the 50s subunit of bacteria 70s ribosomes, inhibiting transpeptidase, hindering the growth of peptidase, inhibiting the formation of peptide chains, thereby preventing protein synthesis and Antibacterial purpose. This product has a broad antibacterial spectrum, and it has a strong effect on Gram-positive bacteria, Gram-negative bacteria and Mycoplasma. This product is rapidly absorbed orally, widely distributed, with long half-life, high blood drug concentration, and long blood drug maintenance time.

Florfenicol structure

The benzonic acid molecule contains the three-part structure necessary for antibacterial activity-D-threo configuration, a strong electron-withdrawing functional group (methyl sulfone group) connected to the benzene ring, and 1,3-propanediol structure (a fluorine atom replaces the propane chain 3 carbon After the hydroxyl group on the position, its antibacterial activity is stronger). FS-Na esterifies the succinyl bridge with the hydroxyl group at the 1 carbon position of the florfenicol propane chain, blocking the hydroxyl active group at that position; and the succinyl bridge also has a certain steric hindrance effect on the fluorine atom. The activity of the original drug was greatly reduced, and the antibacterial activity of FS-Na was significantly lower than that of florfenicol, indicating that the original drug was successfully latent. (In vitro antibacterial activity is inactive).

Florfenicol uses

Florfenicol was initially mainly used in aquaculture for the treatment of pseudonuclear pasteurosis and streptococcus disease of yellowtail, and the natural outbreak of the Atlantic salmonellosis. Animal-specific antibacterial drugs are used for bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, especially for respiratory infections and intestinal infections.

Florfenicol Dosage

Mixed drinking poultry: 3-4g 100L water, livestock, 20-25 mg per kilogram body weight, once a day for 3 days.
Intramuscular injection: Chicken, pig, and cattle are weighed at 15-20 mg per kilogram of body weight, once every 48 hours, and used twice.

Florfenicol veterinary

Florfenicol for dogs

Florfenicol can be used to treat dogs with cold and runny nose, can be used to treat bacterial respiratory infections, and is also effective for mycoplasma. There is no problem in treating common colds, but some viral infections and cold symptoms are similar, such as dog vice Flu, etc. At this time, the use of florfenicol has no effect, it is recommended to seek medical treatment in time.

Florfenicol cattle

Respiratory tract infections, mastitis, mastitis in cattle and sheep; infectious pleural pneumonia, swine asthma, piglet red, (yellow, white) dysentery, erythrozoonosis, streptococcal disease, edema disease, atrophic rhinitis, Pneumonia, erysipelas, sow mastitis and endometritis are very effective.
Oral: 20-30 mg / kg for cattle and sheep (that is, 100g for 500 kg body weight) twice a day for 3-5 days.

Florfenicol in swine

It is used to prevent and treat swine asthma, infectious pleurisy pneumonia, atrophic rhinitis, swine pneumonia, and streptococcal disease. The curative effect is effective for Escherichia coli and other causes of yellow and white dysentery, enteritis, blood dysentery and edema disease of piglets.

Florfenicol in poultry

It is used to prevent poultry cholera caused by Escherichia coli, Salmonella, Pasteurella, etc., chicken diarrhea, diarrhea, stubborn diarrhea, yellow, white and green stools, watery feces, diarrhea, spotted or diffuse bleeding of intestinal mucosa, Chronic respiratory disease caused by omphalitis, pericardium, liver, bacteria, mycoplasma, infectious rhinitis, airbag turbidity, cough, tracheal rattling, dyspnea, etc.

Florfenicol side effects

Because chloramphenicol has serious adverse reactions to aplastic anemia (Varma, et al, 1986), many countries have banned the use of chloramphenicol in the prevention and treatment of animal diseases, especially food animals, such as the US FDA. Studies have shown that the para-nitro group on the aromatic ring in the structure of chloramphenicol is the main group causing aplastic anemia, and the structure of florfenicol with H3C-SO2 instead of O2N does not produce aplastic anemia. Response, so in the prevention and treatment of animal diseases, especially food animals, florfenicol will replace chloramphenicol, which has broad application prospects in veterinary clinics

Florfenicol Precautions

1. The medicine bait after mixing should not be placed for a long time;
2. This product should be properly stored to avoid misuse of people and animals;
3. Dispose of the waste packaging after use properly.

Summary

Florfenicol belongs to the class of amido alcohol antibiotics. It has good effects on many pathogens. It is also a commonly used medicine in chickens. It is used to treat E. coli, mycoplasma, chicken cholera, staphylococcus, and salmonella. However, many farms do not use florfenicol according to the standard, which may cause florfenicol residues in chicken. Excessive intake of florfenicol is harmful to the human body.
The detection of florfenicol is very necessary. The Florfenicol Test For Chicken kit provided by BALLYA can effectively and quickly detect whether chicken contain florfenicol residues. Not only is the operation simple and the detection time is short.

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