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Dimetridazole Test For Chicken Liver(R&D)

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beta-lactams-Test-Kit

For chicken liver

Specs:96T / box
Testing Time:7-10 mins
Worldwide shipping, free sample

Instrution For Dimetridazole Test For Chicken Liver

Introduction
Single Test Kit, rapid to detect an antibiotic residues in milk and dairy product by using colloidal gold immunochromatography technology. As soon as 7-10 minutes to results.

Application
For raw milk, whole milk powder, Pasteurized milk.

Spicifications
1. Specificity
Not cross-react with macrolides, aminoglycosides, sulfonamides drugs, etc.

2. Limit of Detection
Refer to instruction.

Storage & Shelf-Life
At 2~8℃ out of sunlight, 12 months

Compolents (96T / box)
Instruction                          1
Tube                                     12

Equipments (Option)
Timer
Incubator
Mini Pipette(200μL)
Tips for mini pipette
Reader

Operations
1. Take 200 μL milk specimen, add into micro well, mix with the pink agent 10 times.
Remark: avoid specimen residues too much in the well.
2. Incubate 3 minutes
3. Insert strips into the wells
4. Incubate 5 minutes
5. Take out strips and read results by eye or reader.

Interpretation
Visual inspection
1. If C line visible, interpret according to the instruction. T line compare with C line to interpret positive or negative.
2. If C & T are invisible, it’s invalid detection, repeat testing again.

Reader Interpretation
Refer to the instruction

Results Illustration

If you want to know more, please contact us

Trivia questions: Do you know dimetridazole?

About dimetridazole

Dimetridazole (DMZ) is a derivative of metronidazole. It is a white or yellowish powder. It is gradually black when exposed to light and is odorless. Dissolved in ethanol, slightly soluble in ether or water. Dimetridazole is mainly used for avian vibrio hepatitis, trichomoniasis of turkey tissue, and trichomoniasis of avian.

Dimetridazole character

The product is a kind of white or slightly yellow powder, which gradually turns black when exposed to light, and is odorless or almost odorless. Light yellow needle crystal or crystalline powder. Melting point 138-139 ° C. Soluble in chloroform, ethanol, dilute alkali and dilute acid, insoluble in water and ether. Tasteless. Metronidazole hydrochloride is soluble in water, ethanol, and slightly soluble in acetone. Storage conditions: 2-8 ° C. Stable, easy to react with strong oxidants.

Dimetridazole mechanism of action

Broad-spectrum anti-anaerobic bacteria and antiprotozoal drugs have a killing effect on trichomoniasis and a certain inhibitory effect on coccidia.

Dimetridazole uses

Dimetridazole Indications

Mainly used for avian vibrio hepatitis, necrotic tissue, turkey tissue trichomoniasis, poultry trichomoniasis, etc., also has a good effect on cattle trichomoniasis.

Dimetridazole interaction

1. Due to some toxic reactions of dimenidazole, it cannot be used in combination with other anti-tissue trichomoniasis drugs.
2. Dimenidazole can be used in combination with sulfa drugs and TMP for the prevention and treatment of intestinal diseases caused by avian coccidiosis, coccidiosis and bacterial infection.

Dimetridazole and metronidazole

The most intuitive difference is that metronidazole is a human medicine, and dimenidazole is a veterinary medicine. Metronidazole has a broad-spectrum effect against anaerobic bacteria and antiprotozoa. It is mainly used to treat or prevent systemic or local infections caused by anaerobic bacteria, such as the abdominal cavity, digestive tract, and female reproductive system. There is also trichomonas vaginitis. Dimenidazole is also resistant to trichomoniasis and spirochetes. It is mainly used for trichomoniasis in turkey, trichomoniasis in pigeons and blood dysentery in piglets caused by Treponema pallidum.

Dimetridazole veterinary medicine

Dimetridazole This product can also be used as a growth promoter to promote the production of pigs and chickens and improve feed conversion rate. Therefore, the drug is widely used in poultry production.

Dimetridazole uses

1. When this product is used as a feed additive, pre-mix this product with 10-20 times the amount of feed during feed processing, and then mix it evenly with the total amount of feed required.
2. When processing compound feed, granulation and other operations have no effect on the effect of this product.
3. The product can be mixed with feed or added to drinking water for livestock and poultry.
4. The product is rapidly absorbed in the intestine, distributed in various tissues, enters the intestine and liver circulation through the biliary tract.
5. In the poultry body, it is excreted after oxidation, reduction and metabolism. Most of the residues in the carcass were destroyed after 48h or after cooking.

Dimetridazole dosage

Mixed feeding: per kilogram of feed, 500 mg of tissue trichomoniasis is treated, and 160 to 200 mg of poultry to prevent tissue trichomoniasis.
Mixed drink: per liter of water, poultry prevention amount 150 mg, treatment (tissue trichomoniasis) 300-400 mg, treatment of poultry trichomoniasis, pigeon 500 mg, continuous use for 5-8 days.

Dimetridazole deficiency

(1) Dimenidazole has a bitter taste and will affect palatability after oral administration, resulting in a reduction in feed intake. Especially in the treatment of diseases, the intake of drugs leads to insufficient drug intake, which affects the clinical efficacy;
(2) Metronidazole is highly irritating to the respiratory mucosa of poultry, with obvious side effects;
(3) The original powder of Dimenidazole is easily affected by various acids, bases and enzymes during the absorption process in poultry, resulting in a reduction in the efficacy of the drug;
(4) Dimenidazole currently used does not have slow-release properties, resulting in low bioavailability. The existence of the above-mentioned problems not only restricts the full exertion of the drug efficacy of dimenidazole, but also affects the production performance, growth rate and economic benefits of poultry. Dimennidazole (DMZ) is a nitroimidazole drug with antiprotozoal and antibacterial activity, and has a strong anti-anaerobic effect. It is used to treat trichomoniasis of chicken tissues, Treponema pallidum dysentery, intestine and whole body Anaerobic infections. But it is carcinogenic, mutagenic and potentially toxic. The main metabolite of dimenidazole, hydroxydimenidazole (hv-dfoxydinetridazole, DMZOH), may also be mutagenic. Both the European Union and the United Kingdom list dimenidazole as a banned veterinary drug. China sets the MRL of dimenidazole as 0.

Summary

It can be used as a growth promoter to promote broiler production and improve feed conversion rate. Therefore, the drug is widely used in poultry production. Although dimenidazole plays an extremely important role in poultry production, there are still some shortcomings. It is carcinogenic, mutagenic and potentially toxic. The main metabolite of dimenidazole hydroxydimenidazole (hv-dfoxydinetridazole, DMZOH) may also be mutagenic.
The detection of dimenidazole is very necessary. The Dimetridazole Test For Chicken Liver kit provided by BALLYA can effectively and quickly detect whether chicken liver contain dimenidazole residues. Not only is the operation simple and the detection time is short.

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