Clenbuterol + Ractopamine Test (Urine)

Ractopamine is a synthetic Clembaam beta adrenal receptor agonist that can be used to treat congestive heart failure, muscular dystrophy, grow muscle, reduce fat accumulation, and benefit the fetus and newborn. Ractopamine is being used by some pig farms as a new type of lean meat extract.

When used as a food additive, ractopamine added to the feed can be distributed to muscle tissue through the blood, acting as a full agonist on mouse (not necessarily human) TAAR1 in the muscle tissue, and also on β-adrenal Receptor agonist. A series of events will then be initiated to increase protein synthesis, resulting in increased muscle fiber size. It is known that ractopamine can increase weight gain rate, improve feed efficiency, and increase car body leanness in finishing pigs. Its use in pig fattening can add an additional 3 kilograms (6.6 pounds) of lean pork and increase feed efficiency by 10%.

Ractopamine hydrochloride is a medicinal material, a cardiotonic drug that can be used to treat congestive heart failure. It can also be used to treat muscular dystrophy, grow muscle, reduce fat accumulation, and be beneficial to fetal and newborn growth. The US FDA approved it in 2010 and can be used for animal nutrition re-formulation, and is widely used in animal husbandry and aquaculture. It can simultaneously increase the daily weight gain of animals, increase feed utilization, and increase protein content of animals.

Ractopamine is far less toxic than other lean extracts with the same function. Conventional doses of Clenbuterol can be metabolized and excreted in the body without causing harm to the body. However, excessive intake of ractopamine can cause different degrees of toxic reactions in the human body. The symptoms are similar to those of animal poisoning. Symptoms include muscle tremor, paralysis of the limbs, tachycardia, arrhythmia, abdominal pain, muscle pain, nausea and dizziness. Severe cases can cause hypertension, heart disease and even death.

Poisoning of meat or internal organs containing ractopamine residues may cause symptoms of poisoning such as dyspnea, nausea, vomiting, dizziness, headache, muscle tremors, palpitations, arrhythmia, increased blood pressure, promotion of cardiovascular disease, and reproductive system and many more.

The indirect competition ELISA method is used to detect ractopamine in the sample. The antigen is precoated on the microwell strips. The ractopamine in the sample will compete with the precoated antigen on the microwell strips to compete against the ractopamine antibody. After labeling, the color was developed with TMB substrate, and the absorbance value of the sample was negatively correlated with the content of ractopamine in the sample. Compared with the standard curve, the residual amount of ractopamine in the sample could be obtained.

Clenbuterol is a collective name for a class of drugs. Any substance that can inhibit animal fat production and promote lean meat growth can be referred to as "clenbuterol." Clenbuterol is usually referred to. This type of "lean extract" can change the metabolic pathways of nutrients after entering the animal body, promote animal muscle growth, especially promote skeletal muscle protein synthesis, accelerate fat conversion and decomposition, and increase the lean meat rate of livestock.

If the pork containing "Clenbuterol" is consumed by humans, the clinical manifestations will be as follows:
1. Acute poisoning can cause palpitations, facial and neck, limb muscles trembling, hands shaking, or even standing, dizziness and fatigue;
2. Patients with existing arrhythmia are more likely to respond, such as tachycardia, ventricular premature beats, S-T segment depression and T-wave inversion on ECG;
3. Patients with original hypersympathetic nerve function, such as high pressure, coronary heart disease, and hyperthyroidism, the above symptoms are more likely to occur;
4. Combination with glucocorticoids can cause hypokalemia, which leads to arrhythmia.

This product is an adrenaline bronchial antispasmodic drug. It has good selectivity for the stimulation of bronchial smooth muscle β2 receptors, and the intensity of bronchodilator expansion is 100 times that of Shuchuanning. For the treatment of bronchial asthma, asthmatic bronchitis, etc.

"Clenbuterol" is very harmful to people, mainly manifested in: palpitations during acute poisoning, facial and neck, limb muscle tremor, finger tremor, foot feeling deep or even unable to stand, headache, dizziness, nausea, vomiting, fatigue, Flushed face, allergic red pimples on the skin. Those with high blood pressure, coronary heart disease, and hyperthyroidism are more likely to have the above symptoms, and the harm to mammals is similar. Sudden death can even occur when stress is weak and stress factors are present for a long time. Feeding lean meat pigs, acute heart failure often occurs during long-distance trafficking, leading to sudden death. Clenbuterol hydrochloride is stable in nature and will not decompose when heated to 172 ° C, so ordinary cooking methods cannot destroy its structure at all. Studies have shown that if eaten for a long time, it will also lead to the possibility of chromosomal aberrations and induce malignant tumors.

In recent years (2011), poisoning incidents caused by consumption of foods contaminated with "lean extract" have repeatedly occurred, with extremely serious consequences, which has drawn great attention from countries around the world. Although China proposed to ban the use of "clenbuterol" drugs in 2000, the use of "clenbuterol" in animal husbandry production is still banned.
The RS Collaurum Labeling Dual Sensor Test kit provided by BALLYA can effectively detect whether food contains clenbuterol. This kit is not only simple to operate, but also has a short test time and high accuracy. Can ensure consumers Food safety.

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