Carbofuran physical and chemical properties
Pure product is white crystal, no odor, soluble in many organic solvents, hardly soluble in xylene, petroleum ether, kerosene.
Inflammable in case of open flames and high heat. Heat releases toxic nitrogen oxide fumes. The harmful combustion products are carbon monoxide, carbon dioxide and nitrogen oxides.
Synthesis of carbofuran: 16.6 parts by mass of 7-hydroxy compound in 14 parts by mass of ether with 5.8 parts by mass of isocyanic acid and 0.1 parts by mass of triethylamine. After stirring, a white crystalline product precipitated. The solid crystal was separated to obtain 17.5 parts of Budweiser.
O-nitrophenol is reacted with 3chloroisobutylene to form 2-isobutenyloxynitrobenzene, and then Claisen metathesis rearrangement is performed at 175 ~ 190 °C, and cyclization reaction (chlorination at 150 ~ 190 °C Iron is an acidic catalyst) to produce 2,3-dihydro-2,2-dimethyl-7-nitrobenzofuran. After hydrogenation reduction, diazo is present at room temperature or low temperature in the presence of sulfuric acid and sodium nitrite. Into. The reactant was hydrolyzed to 7-hydroxybenzofuran by heating, and then reacted with methyl isocyanate to obtain cloveamide. -Usually made into 75% mother powder, processed into granules
is a carbamate broad-spectrum systemic insecticide and acaricide. It can be used to control more than 300 pests and nematodes on soil and ground for various crops. It also has the effect of shortening the crop growth period, promoting crop growth and development, and effectively increasing crop yield. The toxic effects of carbofuran on insects are mainly systemic insecticides. The drug is used in the roots of soil crops. The root system absorbs water and transports it to the stems and leaves, thereby achieving the purpose of controlling insects. Carbofuran also has a killing effect. It is used to control cotton aphids, rice and corn rootworms. It is effective against most pests such as rice, corn and peanuts.
1. It is suitable for controlling underground pests, foliar pests and nematodes on cotton, rice, sugarcane, peanut, corn, sugar beet and other crops.
2. Wide insecticidal spectrum. It can effectively control ground pests and nematodes such as tigers, maggots, gold needles, maggots, etc., and it can control ground pests such as corn borer and aphids. It has multiple treatments with one drug, a long holding period, and significant comprehensive control effects;
3, can promote crop growth. Furandan can obviously promote the growth of crop roots, is conducive to the cultivation of strong seedlings, and has a significant increase in yield;
4. Easy to use. Can be applied manually or mechanically, saving labor and effort;
5. Furandan is a carbamate-type broad-spectrum systemic insecticide and nematicide with contact killing and stomach toxicity.
6. Carbofuran can be absorbed by plant roots and can be transported to various organs of the plant. It accumulates more in the leaves, especially in the leaf margins, and it is less in the fruit and has a half-life of 30-60 days in the soil.
7. It is a medium toxic product; when used correctly, there is no residual risk and it is safe for food. No residue, no accumulation in the soil, no pollution to groundwater, so it is safe for the environment.
8. Pesticides are sprayed on the water surface of rice fields, the residual effect period is short, and the residual effect period is longer when applied to the soil. The effect can be maintained for about 90 days in cotton and sugarcane fields.
Irritating to eyes, skin and mucous membranes. The acute menstrual LD50 in rats is 8 to 14 mg / kg (1.0 mg / kg for industrial products), and the acute transdermal LD50 is less than 500 mg / kgo in dogs. It is 19 mg / kg, chicken is 9 mg / kgo fish LC501. 5 mg / L (0.28 mg / kg) (96h), industrial products for gill fish, Xiaogill fish LC50 is 0.21-0.28 mg / L. The rats were fed at a dose of 25 mg / kg for 2 years without poisoning. Within the test dose, it has no teratogenic, carcinogenic, and mutagenic effects on animals, and no abnormalities have been seen in the second-generation reproduction test and neurotoxicity test.
It mainly inhibits cholinesterase activity in the body, causing acetylcholine to accumulate in tissues and cause poisoning. Cholinesterase inhibition lasts for a short period of time, and cholinesterase recovers faster after stopping contact. Poisoning manifestations include nausea, vomiting, abdominal cramps, sweating, diarrhea, drooling, weakness, imbalance, blurred vision, dyspnea, and elevated blood pressure.
Carbofuran poisoning symptoms
Dizziness, headache, fatigue, pale, vomiting, sweating, drooling, dilated pupils, blurred vision. In severe cases, blood pressure drops and consciousness develops. Contact dermatitis such as rubella, local redness, itchiness, conjunctival congestion, tearing, chest tightness, dyspnea, etc.
Carbofuran poisoning treatment
Get out of the scene quickly and completely remove poison. Skin contaminated persons, remove contaminated clothing and wash with soap and water repeatedly. Oral poisoning should prompt vomiting and repeated gastric lavage. Gastric lavage fluid with water or 2% ~ 5% sodium bicarbonate solution.
Atropine or scopolamine hydrobromide is used as an antidote. For the usage and dosage, refer to the overview in this section; the oxime reactivator is ineffective. If the product is poisoned by mixing with organophosphorus pesticides, atropine can be used first. According to the needs of the disease, after the poisoning for a period of time, an appropriate amount of oxime rejuvenating agent can be applied as appropriate.
⑶ symptomatic and supportive therapy.
Skin contact: Remove contaminated clothing and rinse with plenty of running water.
Eye contact: Raise eyelids and rinse with running water or saline. Seek medical attention.
Inhalation: Quickly leave the scene to fresh air. Keep your airways open. If breathing is difficult, give oxygen. If not breathing, give artificial respiration immediately. Seek medical attention.
Ingestion: Drink plenty of warm water and induce vomiting. Stomach lavage and drainage. Seek medical attention.
Carbofuran poisoning prevention
Engineering control: closed operation, local exhaust.
Respiratory protection: A dust mask (full face mask) must be worn when it may come into contact with dust. Wear an air respirator for emergencies or evacuation.
Eye protection: Protective in respiratory protection.
Body protection: Wear protective clothing.
Hand protection: Wear rubber gloves.
Other protection: No smoking, eating and drinking at the work site. After work, take a shower. Maintain good hygiene.
The human body is exposed through contact with the contaminated environment or eating, drinking contaminated food and water sources, and can also be inhaled through field spraying. Workshop workers can cause chronic poisoning due to long-term contact.
The Carbofuran Rapid Test kit provided by BALLYA
can effectively test whether the agricultural product contains carbofuran residue. This kit is not only simple to operate, but also has a short test time and high accuracy, and the test results comply with EU standards. Can effectively ensure the safety of agricultural products.